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肝动脉化学灌注栓塞术联合部分脾动脉栓塞术治疗原发性肝癌并脾功能亢进
引用本文:涂强,饶荣生,周新文,何均,温时来.肝动脉化学灌注栓塞术联合部分脾动脉栓塞术治疗原发性肝癌并脾功能亢进[J].江西医药,2011,46(5):403-405.
作者姓名:涂强  饶荣生  周新文  何均  温时来
作者单位:江西省肿瘤医院肝肿瘤诊断治疗中心,南昌,330029
摘    要:目的评估肝动脉化学灌注栓塞术联合部分脾动脉栓塞术治疗原发性肝癌并脾功能亢进的疗效。方法对43例原发性肝癌并脾功能亢进患者行TACE治疗的同时行PSE治疗,观察治疗前后白细胞及血小板变化情况,并观察肝脏肿瘤情况。结果术后1周及1个月复查血常规,WBC和PLT有显著升高(P〈0.01),RBC无明显改变(P〉0.05),术后1个月复查CT示肝脏病灶内均有碘油沉积,脾脏有脾实质梗死区域,未出现严重并发症。结论 TACE联合PSE治疗原发性肝癌并脾功能亢进是安全、有效的。

关 键 词:原发性肝癌  脾功能亢进  肝动脉化学灌注栓塞术  部分脾动脉栓塞术

Effect of TACE plus PSE in patients wiht HCC with hypersplenism
Affiliation:Tu Qiang,Lao Rongsheng,Zhou Xinwen,et al.Department of liver tumor treatment center,the tumor hospital of Jiangxi province,Nangchang,330029,China
Abstract:Objective To evaluate TACE with PSE treatment of hypersplenism resulting from HCC.Methods 43 cases of HCC-related hypersplenism were treated in this study with TACE and PSE simultaneously,observation being on the hepatic tumors as well as the change in numbers of white cells and blood platelets before and after treatment.Results The blood routine examination,a week and a month after the operation,revealed that WBC and PLT increased significantly(P0.01),while RBC changed insignificantly(P0.05).CT,a month after the operation,discovered lipiodol retention in all liver focal lesions,spleen parenchyma infarction zones in the organ,but no serious complication.Conclusion TACE with PSE treatment of hypersplenism resulting from HCC is secure and effective.
Keywords:primary hepatocellular carcinoma  hypersplenism  transcatheter hepatic arterial chemoembolization  partial splenic embolization
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