Virulence and antifungal susceptibility of microsatellite genotypes of Candida albicans from superficial and deep locations

A set of 185 strains of Candida albicans from patients with vulvovaginal candidiasis (VVC) and from non-VVC clinical sources in southwest China was analysed. Strains were subjected to genotyping using CAI microsatellite typing and amplification of an intron-containing region of the 25S rRNA gene. Microsatellite genotypes of strains from non-VVC sources showed high polymorphism, whereas those of VVC were dominated by few, closely similar genotypes. However, among non-VVC strains, two genotypes were particularly prevalent in patients with lung cancer. 25S rDNA genotype A was dominant in VVC sources (86.7%), whereas genotypes A, B, and C were rather evenly distributed among non-VVC sources; known genotypes D and E were not found. In an experimental mouse model, isolates from lung cancer and AIDS patients proved to have higher virulence than VVC strains. Among 156 mice infected with C. albicans, 19 developed non-invasive urothelial carcinoma. No correlation could be established between parameters of virulence, source of infection, and incidence of carcinoma. C. albicans strains from VVC were less susceptible to itraconazole than the strains from non-VVC sources, whereas there was small difference in antifungal susceptibility between different 25S rDNA genotypes of C. albicans tested against amphotericin B, itraconazole, fluconazole, and flucytosine.     

篮球技术多媒体CAI课件在体育教学中的研究与应用价值分析

随着科学技术水平的不断提高，在学校教育中应用多媒体CAI的现象越来越普遍，并且受到了广大师生的喜爱。在篮球技术教学中，多媒体CAI课件得到了广泛的应用，并且发挥了非常重要的作用，促进了学生篮球技术水平的提高，实现了预期的教学效果。     

基于Web的多煤体CAI课件开发过程中若干问题的研究和实践

基于Web的多煤体CAI课件是多媒体CAI课件与Web技术的结合,它将成为网络教学多媒体CAI课件的主要形式。该文结合一个实例,介绍了在基于Web的多媒体CAI课件开发过程中,对课件页面进行页面优化的原则方法,并详细介绍了课件中导航、查询、测试等关键功能的JavaScript程序实现技术和方法     

计算机辅助教学（CAI）的展望

简述了ＣＡＩ这种新兴的教育技术，并从多媒体技术、网络技术人工智能技术等方面探讨了其发展前景。     

Analytical approaches to compression after impact (CAI) behavior of carbon fiber-reinforced composite materials

Analytical efforts to understand problems involving compression after impact (CAI) are reviewed. A theoretical solution of beam plate modeling is introduced to understand the buckling of multiple delaminated plates. Numerical efforts on CAI-related matters for rectangular plates are then briefly described to show the difficulties in evaluating the effects of the various factors on the compressive properties of impact-damaged laminates. Also, the reason for the simplification of the double-spiral damage to multiple circular delaminations is briefly explained from a mechanical viewpoint. Analytical schemes to evaluate the compressive strength of the impact-damaged laminates are introduced based on fracture mechanics. The accuracy and meaning of the solutions are discussed by comparing the present solutions with finite element analysis results.     

利用ActiveX技术制作通信课程CAI课件

通信课程的CAI课件,要求不仅仅有原理和技术的展示,还要能够与用户实时交互。为实现该类课件的制作,利用PowerPoint中内嵌的VBA调用Matlab ActiveX进行实时计算和绘图,然后将处理结果返回到当前窗口加以显示。如此,可以增强课件的交互能力,激发学生的学习兴趣和参与意识,同时深刻理解和掌握通信的原理和技术,达到事半功倍的效果。     

岩石磨蚀性指数分级讨论

隧道施工中,岩石的磨蚀性是影响各类破岩工具磨损的主要因素之一。国际上设计了许多评价岩石磨蚀性的小型试验,其中Cerchar试验因其操作简易性获得了普遍应用,其结果CAI(Cerchar Abrasivity Index)值能够较好地预测破岩工具连续、平稳的正常磨损,目前我国也广泛采用该试验进行岩石磨蚀性评价。由于我国引进该试验时间较晚,尚无国家试验规范,CAI值的等级划分不明确。本文收集了国际上各试验室与机构使用的分级标准,从CAI值分级所用的钢针硬度、CAI值对应的破岩工具磨损量、大量试验数据的分布3个方面综合比较,认为国际岩石力学协会推荐的CAI值分级比较合理。本文对国内Cerchar试验规范创立、岩石磨蚀性评价具有借鉴意义。     

中国民间传统家具创新模式的研究

以传统家具的仿制或者改良一度成为家具设计、生产热点的现象为启示,分析了民间传统家具的当代文化价值以及民间传统家具造物观的当代设计价值。民间传统家具产生和发展的社会物质技术条件和文化背景决定了民间传统家具必须创新才有发展。在此基础上,提出了基于CAI技术的设计创新、家具材料的创新和中间技术的家具生产方式创新等3种创新模式。     

篮球中锋个人进攻与防守技术CAI多媒体教学课件的研制分析

篮球中锋个人进攻与防守技术CAI多媒体教学课件的研制的制作鉴于篮球中锋的特点，根据新时期的教学目标，依托现代多媒体技术，使篮球教学更加生动形象，丰富多彩。本文将运用CAI多媒体教学课件分析研制篮球中锋个人进攻与防守技术，使学生更好掌握篮球中锋方面技术知识。     

基于信息管理的应用型塑性成形CAI系统

研究一种基于信息管理的应用型CAI系统，它适用于塑性成形以及与之特点相近的工程学科。用户可以根据需要自行生成、组织和管理CAI教学内容并形成具有生产实用功能的CAI运行体系，有利于教与学创造性的发挥并适应知识更新发展的需求。