篮球运动中学生损伤病因与预防

通过对体育院系学生问卷调查，了解学生在篮球运动中发生运动损伤病因，提出预防措施。     

线粒体蛋白组研究进展

线粒体蛋白组是指在线粒体中出现的所有蛋白质的集合,包括线粒体自身基因组编码的和 由核基因组编码的蛋白质.线粒体作为真核生物的重要细胞器,它参与去除氧化、产生能量和还原 性物质等等一些重要的生命活动过程.这些功能都依赖于线粒体蛋白组中的蛋白河的相互作用.要 对其有一个较为全面的认识,就必须对其蛋白组进行广泛且深入的研究.根据现有的一些研究成 果,对线粒体蛋白组在起源与进化、跨膜运输、研究方法和计算机预测作了简要综述.     

田径运动肌肉损伤及康复对策研究

在田径教学、训练与比赛中,由于没有完全遵循人体运动的生理规律和调控生物节律,不能使机体的工作运行保持在良好的竞技状态,导致各种各样的运动创伤,严重地影响教学、训练与运动成绩的提高.文章从运动医学理论对田径运动中肌肉损伤的原因进行分析,寻找科学的田径运动损伤康复手段。     

Targeted inhibition of Livin resensitizes renal cancer cells towards apoptosis

Cancer cells are typically characterized by apoptosis deficiency. In order to investigate a possible role for the anti-apoptotic livin gene in renal cell cancer (RCC), we analyzed its expression in tumor tissue samples and in RCC-derived cell lines. In addition, we studied the contribution of livin to the apoptotic resistance of RCC cells by RNA interference (RNAi). Livin gene expression was detected in a significant portion of RCC tumor tissue specimens (13/14, 92.9%) and tumor-derived cell lines (12/15, 80.0%). Moreover, targeted inhibition of livin by RNAi markedly sensitized RCC cells towards proapoptotic stimuli, such as UV irradiation or the chemotherapeutic drugs etoposide, 5-fluorouracil, and vinblastine. These effects were specific for livin expressing tumor cells. We conclude that livin can contribute significantly to the apoptosis resistance of RCC cells. Targeted inhibition of livin could represent a novel therapeutic strategy to increase the sensitivity of renal cancers towards pro-apoptotic agents. Received 30 November 2006; received after revision 22 February 2007; accepted 20 March 2007     

胸部创伤324例分析

对 32 4例胸外伤患者经抢救治疗后 ,除 1例锁骨下静脉吻合术患者术后死于急性肾功能衰竭外 ,其余均痊愈出院 .并对胸外伤患者抢救治疗原则进行了分析     

高校竞技健美操运动员腕部损伤的原因及康复手段

通过调查与访谈,对参加江苏省16届运动会高校部健美操比赛的运动员手腕部的运动损伤情况进行统计与分析,总结出造成手腕部运动损伤的原因及康复治疗的手段,以期减少不必要的运动损伤,为竞技健美操教学与训练提供有效帮助。     

高水平大学生足球运动员运动损伤的调查与分析

通过对参加2004-2005飞利浦中国大学生足球联赛南区决赛的156名高水平大学生足球运动员进行调查研究,对其运动损伤的特征、易发部位及原因进行了分析,并提出了相应的预防措施,以增强大学生足球运动员的防伤病意识,从而更好的促进高校足球运动的发展。     

Frequent mtDNA mutations and its role in gastric carcinogenesis

In order to disclose the relationship between mutations of mitochondrial DNA (mtDNA) and gastric carcinogenesis, we screened the entire mtDNA sequence in 30 cases of human gastric cancer and matched normal tissues by using denaturing high-performance liquid chromatography (DHPLC) and DNA sequencing. Our data showed that high frequency (66.7%, 20/30) of mitochondrial genome mutation occurred in gastric cancer. Among these variants, 17 cases (56.7%, 17/30) were identified to be somatic mutation. High level mutant frequency was found in ND4, ND5 coding genes and D-loop control region, which was 36.7%, 26.7% and 30% respectively. Comparing with complexes Ⅲ, Ⅳ and Ⅴof the electron transport chain, we found that variants appeared to be more frequent in the subunit genes of complexⅠ. Most of mutations were base substitutions (85.4%, 41/48). Our results suggested that mutations of subunit genes encoding complexⅠ, especially ND3, ND4 and ND5 genes, might contribute to human gastric carcinogenesis.     

监护职责和监护责任--以《学生伤害事故处理办法》第7条为例

监护职责与监护责任在实际生活中往往被混为一谈。在处理学生伤害事故时，学校和监护人的责任，到底是一种什么责任，也往往引起人们的误解。监护职责与监护责任属于不同的范畴，两者在内容和能否约定转移上都有着明显的不同。