ROS scavenging Manganese-loaded mesoporous silica nanozymes for catalytic anti-inflammatory therapy

Reactive oxygen species (ROS) are reactive substances closely related to the inflammatory response, and previous studies have shown that anti-inflammatory therapy can achieve significant effects by scavenging ROS. Nanozymes are synthetic mimics of natural enzymes that are more stable, customizable, inexpensive, and catalytic for ROS. Therefore, we prepared a novel manganese-loaded mesoporous silica nanozyme (MnMSN) by template method and KMnO₄ oxidation surfactant templates. The physicochemical properties of the nanomaterials were investigated by XRD, TEM, SEM, size, Zeta potential and BET, etc. The results showed that MnMSN contains MnO₂ (Mn⁴⁺) and MnSiO₃ (Mn²⁺), and the particle size of MnMSN is smaller with the increase of KMnO₄ oxidation surfactant templates time, and the in vitro scavenging of ROS (H₂O₂, ·OH and ·O₂^–) is more effective. MnMSN has good cytocompatibility, scavenging intracellular ROS and inducing a shift from M1 to anti-inflammatory M2 phenotype. Furthermore, the intrinsic mechanism of MnMSN regulation of macrophage polarization was investigated by ELISA and qPCR, and the results showed that MnMSN is through scavenging ROS, leading to the down-regulation of NF-κB, which further leads to the down-regulation of TNF-α and IL-Iβ. The results of this work highlight the potential of MnMSN in catalyzing anti-inflammatory therapy.     

负载型Ni/C催化对硝基酚加氢制备对氨基酚

以Ni/C为催化剂,催化对硝基酚加氢制备对氨基酚。优化了工艺条件,选用10%Ni/C作为催化剂,研究了温度,压力,催化剂加入量对反应的影响。在100℃,2 MPa下,对氨基酚的选择性大于99%。     

一种含能硝基化合物对低燃速低燃温双基推进剂性能影响

为进一步降低低燃速低燃温双基推进剂的燃速、燃温,对一种含能硝基化合物的降温、降速效果进行了实验研究,设计了系列含无机铅盐、有机铜盐及过渡元素金属催化剂的双基配方。通过燃速测试及高压差示扫描量热法(PDSC)研究上述推进剂的燃烧性能和热分解特性。含该硝基化合物的推进剂DSC曲线呈三峰放热,放热峰峰温分别在200℃、280℃、350℃左右,第三峰不明显。结果表明:该含能硝基化合物能有效降低推进剂的燃速、燃温,但使推进剂的压强指数增大,而加入催化剂能改善推进剂的燃烧性能,使压强指数降低,分解放热量也降低。     

甲壳质─钯加氢催化剂的催化性能研究

本文研究了高分子金属加氢催化剂：甲壳质的钯配合物．（以下简称ＣＴ－Ｐｄ）．实验发现，在常温、常压下，ＣＴ－Ｐｄ配合物能对烯烃、芳香族化合物以及丙烯酸进行高效催化加氢．     

热氧化温度对Ru_(0.15)Ir_(0.15)Ti_(0.7)/Ti电极性能的影响

应用刷涂-热氧化法,在不同热氧化温度(分别为400℃、440℃、470℃)下制备Ru、Ir、Ti三元金属氧化物电极。通过电化学性能、强化寿命以及电极形貌分析得出:440℃热氧化温度下制备的Ru0.15Ir0.15Ti0.7/Ti电极析氯电位低、催化活性强、强化寿命长;且该温度下的反应电阻也最小。     

微波催陈白酒试验装置的研制

设计一套微波催陈白酒的试验装置，使酒的后熟贮存期缩短，确定了微波催陈白酒的工艺路线及控制参数。研究了该试验装置中能量交换器的设计，探讨了微波泄漏的可能部位及预防措施。     

Zn^2＋类催化剂催化松香酯化反应

本文研究了Zn~(2+)类固体酸催化松香酯化反应的规律。探讨了温度、催化剂用量、制法对酯化反应的影响。改进了280℃下的反应。不同方法制备的氧化锌,其催化效率不尽相同。     

Enhanced hydrogen generation from Al-water reaction mediated by metal salts

Hydrogen generation by the reaction of micrometer-aluminum powder with water at room temperature is hard to proceed due to the inhibition of alumina layer. In this study, a novel strategy of metal salts mediated Al-water reaction was proposed for more efficient and practical hydrogen generation. The effects of metal salt composition and dosage, and water injection rate and volume on hydrogen generation were investigated. The hydrogen yield of 230.0 mL was achieved in the Al/Ni/Cu/H₂O system within 600 s under the following conditions: 0.24 g aluminum with the molar ratio of Al, Ni and Cu at 10:1:1 and 2 mL water at the injection rate of 2 mL/min, which was equivalent to 70.4% of the theoretical hydrogen yield. Based on the morphology, element composition, crystal structure and electrochemical test results of the obtained composites after reaction, the mechanism of hydrogen production by metal salts mediated Al-water reaction was proposed.     

Catalytic coal partial gasification in an atmospheric fluidized bed

The coal partial gasification catalyzed by limestone, sodium carbonate and dolomite was studied using a bench-scale atmospheric fluidized bed in the presence of air and steam at 900 °C. The effects of limestone, sodium carbonate and dolomite on composition, heating value, gas yield of product gas and carbon conversion in the catalytic coal partial gasification have been examined. The experimental results show that the catalysts can effectively improve the gas quality, the heating value and the gas yield of product gas and carbon conversion. The catalytic effect of sodium carbonate is better than that of limestone and dolomite. The increase of limestone loading can enhance the quality of product gas, such as the content of combustible gas, the high heating value and the gas yield, during coal partial gasification. This work was presented at the 6 ^th Korea-China Workshop on Clean Energy Technology held at Busan, Korea, July 4–7, 2006.     

微波辐射硫酸铁铵催化合成乙酸正丁酯的研究

以硫酸铁铵为催化剂,采用微波辐射的方法催化合成乙酸正丁酯。讨论了微波辐射的功率、反应时间、酸醇摩尔比、催化剂的用量以及分水因素对酯化反应的影响。通过单因素实验确定合成乙酸正丁酯的最佳反应条件为：微波辐射功率为240W,辐射时间为15min,催化剂用量为1．3g,酸醇比为1．2：1．0,酯化率为98．2％。本方法具有反应时间短、反应条件温和、后处理简单且环保无污染等特点。