全文获取类型
收费全文 | 17853篇 |
免费 | 1273篇 |
国内免费 | 138篇 |
学科分类
医药卫生 | 19264篇 |
出版年
2023年 | 205篇 |
2022年 | 183篇 |
2021年 | 679篇 |
2020年 | 425篇 |
2019年 | 539篇 |
2018年 | 689篇 |
2017年 | 498篇 |
2016年 | 572篇 |
2015年 | 641篇 |
2014年 | 801篇 |
2013年 | 1051篇 |
2012年 | 1496篇 |
2011年 | 1512篇 |
2010年 | 836篇 |
2009年 | 763篇 |
2008年 | 1265篇 |
2007年 | 1180篇 |
2006年 | 1085篇 |
2005年 | 961篇 |
2004年 | 880篇 |
2003年 | 784篇 |
2002年 | 603篇 |
2001年 | 148篇 |
2000年 | 148篇 |
1999年 | 135篇 |
1998年 | 115篇 |
1997年 | 86篇 |
1996年 | 64篇 |
1995年 | 68篇 |
1994年 | 67篇 |
1993年 | 43篇 |
1992年 | 71篇 |
1991年 | 74篇 |
1990年 | 66篇 |
1989年 | 63篇 |
1988年 | 56篇 |
1987年 | 63篇 |
1986年 | 61篇 |
1985年 | 48篇 |
1984年 | 40篇 |
1983年 | 18篇 |
1982年 | 19篇 |
1981年 | 13篇 |
1980年 | 14篇 |
1979年 | 16篇 |
1978年 | 13篇 |
1976年 | 14篇 |
1975年 | 12篇 |
1974年 | 11篇 |
1968年 | 9篇 |
排序方式: 共有10000条查询结果,搜索用时 16 毫秒
1.
2.
Olivari Davide De Giorgio Daria Staszewsky Lidia Irene Fumagalli Francesca Boccardo Antonio Novelli Deborah Manfredi Martina Babini Giovanni Luciani Anita Ruggeri Laura Magliocca Aurora Zani Davide Danilo Masson Serge Belloli Angelo Pravettoni Davide Maiocchi Giuseppe Latini Roberto Ristagno Giuseppe 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2022,36(4):727-738
Cardiovascular Drugs and Therapy - Available animal models of acute heart failure (AHF) and their limitations are discussed herein. A novel and preclinically relevant porcine model of decompensated... 相似文献
3.
Paul G. Richardson Fredrik Schjesvold Katja Weisel Philippe Moreau Larry D. Anderson Darrell White Paula Rodriguez-Otero Pieter Sonneveld Monika Engelhardt Matthew Jenner Alessandro Corso Jan Dürig Michel Pavic Morten Salomo Meral Beksac Albert Oriol Jindriska Lindsay Anna Marina Liberati Monica Galli Pawel Robak Alessandra Larocca Munci Yagci Filiz Vural Abraham S. Kanate Ruiyun Jiang Lara Grote Teresa Peluso Meletios Dimopoulos 《European journal of haematology》2022,108(1):73-83
4.
Carlo Romano Settanni Gianluca Ianiro Francesca Romana Ponziani Stefano Bibb Jonathan Philip Segal Giovanni Cammarota Antonio Gasbarrini 《World journal of gastroenterology : WJG》2021,27(43):7433-7445
In December 2019 a novel coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), started spreading from Wuhan city of Chinese Hubei province and rapidly became a global pandemic. Clinical symptoms of the disease range from paucisymptomatic disease to a much more severe disease. Typical symptoms of the initial phase include fever and cough, with possible progression to acute respiratory distress syndrome. Gastrointestinal manifestations such as diarrhoea, vomiting and abdominal pain are reported in a considerable number of affected individuals and may be due to the SARS-CoV-2 tropism for the peptidase angiotensin receptor 2. The intestinal homeostasis and microenvironment appear to play a major role in the pathogenesis of COVID-19 and in the enhancement of the systemic inflammatory responses. Long-term consequences of COVID-19 include respiratory disturbances and other disabling manifestations, such as fatigue and psychological impairment. To date, there is a paucity of data on the gastrointestinal sequelae of SARS-CoV-2 infection. Since COVID-19 can directly or indirectly affect the gut physiology in different ways, it is plausible that functional bowel diseases may occur after the recovery because of potential pathophysiological alterations (dysbiosis, disruption of the intestinal barrier, mucosal microinflammation, post-infectious states, immune dysregulation and psychological stress). In this review we speculate that COVID-19 can trigger irritable bowel syndrome and we discuss the potential mechanisms. 相似文献
5.
6.
7.
8.
Valentina Guercio Francesca Donato Claudio Pelucchi Federica Verga Valter Passini Carlotta Galeone Eva Negri Giacomo Garzaro Paolo Boffetta Carlo La Vecchia Alessandra Tavani Enrico Pira 《La Medicina del lavoro》2019,110(5):342
Background::Soft tissue sarcoma (STS) is a heterogeneous group of rare neoplasms whose aetiology is largely unknown. Dioxin and dioxin-like compounds, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) and polychlorinated biphenyls (PCBs), are potential risk factors for STS.Objectives:To investigate the relation of 17 PCBs congeners, assessed in human plasma, with STS risk.Methods:We conducted a case-control study in Italy, including 52 STS cases and 99 hospital-based controls. Selected PCB were extracted by high-performance liquid chromatography (HPLC) and measured with gas chromatography-mass spectrometry (GC-MS). Odds ratios (OR), and the corresponding 95% confidence intervals (CI), were estimated through multivariate logistic regression models.Results:The most frequently detected PCB congeners were 138, 170, 180 and 149 (detected in 40-77% of controls). The OR for the sum of all 17 PCB congeners was 1.20 (95% CI 0.50-2.92). In categorical analysis no consistent association was found for individual congeners and for groups based on Wolff’s classification or the degree of chlorination. For continuous estimates, borderline positive associations emerged for Wolff’s groups 2A (OR 1.23, 95% CI 0.97-1.55), 2B (OR 1.34, 95% CI 1.00-1.77, and 3 (OR 1.19, 95% CI 0.96-1.49), for moderately (OR 1.20, 95% CI 0.96-1.51) and highly (OR 1.18, 95% CI 0.99-1.41) chlorinated PCBs, and for congeners 170 (OR 1.26, 95% CI 0.98-1.63), 180 (OR 1.26, 95% CI 0.97-1.64) and 138 (OR 1.45, 95% CI 1.02-2.04).Discussion:Most associations between PCBs and STS risk were not significant, but, given the limited sample size, we cannot exclude moderate associations.Key words: Soft tissue sarcoma, polychlorinated biphenyls, epidemiology, environmental risk factors, chemical contaminants, case-control study 相似文献
9.
10.
Cristina Masini Maria Giuseppa Vitale Marco Maruzzo Giuseppe Procopio Ugo de Giorgi Sebastiano Buti Sabrina Rossetti Roberto Iacovelli Francesco Atzori Laura Cosmai Francesca Vignani Giuseppe Prati Sarah Scagliarini Annalisa Guida Annalisa Berselli Carmine Pinto 《Clinical genitourinary cancer》2019,17(1):e150-e155