全文获取类型
收费全文 | 851篇 |
免费 | 43篇 |
国内免费 | 1篇 |
学科分类
医药卫生 | 895篇 |
出版年
2023年 | 3篇 |
2022年 | 6篇 |
2021年 | 18篇 |
2020年 | 27篇 |
2019年 | 15篇 |
2018年 | 30篇 |
2017年 | 17篇 |
2016年 | 13篇 |
2015年 | 24篇 |
2014年 | 33篇 |
2013年 | 46篇 |
2012年 | 49篇 |
2011年 | 53篇 |
2010年 | 21篇 |
2009年 | 15篇 |
2008年 | 36篇 |
2007年 | 51篇 |
2006年 | 28篇 |
2005年 | 22篇 |
2004年 | 20篇 |
2003年 | 31篇 |
2002年 | 35篇 |
2001年 | 30篇 |
2000年 | 24篇 |
1999年 | 15篇 |
1996年 | 5篇 |
1995年 | 4篇 |
1992年 | 10篇 |
1991年 | 15篇 |
1990年 | 28篇 |
1989年 | 18篇 |
1988年 | 19篇 |
1987年 | 24篇 |
1986年 | 14篇 |
1985年 | 13篇 |
1984年 | 8篇 |
1983年 | 6篇 |
1982年 | 5篇 |
1981年 | 3篇 |
1979年 | 13篇 |
1978年 | 5篇 |
1977年 | 3篇 |
1975年 | 5篇 |
1974年 | 4篇 |
1973年 | 6篇 |
1971年 | 2篇 |
1970年 | 3篇 |
1969年 | 2篇 |
1967年 | 2篇 |
1966年 | 3篇 |
排序方式: 共有895条查询结果,搜索用时 31 毫秒
1.
2.
Vorkas CK Gopinathan MK Singh A Devinsky O Lin LM Rosenberg PA 《The New York state dental journal》2008,74(2):39-43
This paper is a review of the dental management of patients with epilepsy. It includes discussion of the effects anti-epileptic drugs have on dental procedures and addresses complications and side effects of these drugs. A clinical case photo is presented to show gingival hyperplasia, along with four tables on which common antiepileptic medications are enumerated. 相似文献
3.
4.
5.
Kottoor J Velmurugan N Ballal S Roy A 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2011,111(5):e41-e45
The aim of this article was to present an endodontically managed maxillary first molar with unusual C-shaped palatal root morphology confirmed by cone-beam computerized tomography (CBCT) images. CBCT axial images showed the presence of C-shaped palatal root canal anatomy with a palatal root bifurcation at the apical third. The evaluation of CBCT images can result in better understanding of root canal anatomy, which enables the clinician to investigate the root canal system and to clean, shape, and obturate it more effectively. 相似文献
6.
7.
Chandler RJ Chandrasekaran S Carrillo-Carrasco N Senac JS Hofherr SE Barry MA Venditti CP 《Human gene therapy》2011,22(4):477-481
Propionic acidemia (PA) is an autosomal recessive disorder of metabolism caused by a deficiency of propionyl-coenzyme A carboxylase (PCC). Despite optimal dietary and cofactor therapy, PA patients still suffer from lethal metabolic instability and experience multisystemic complications. A murine model of PA (Pcca(-/-)) of animals that uniformly die within the first 48?hr of life was used to determine the efficacy of adeno-associated viral (AAV) gene transfer as a potential therapy for PA. An AAV serotype 8 (AAV8) vector was engineered to express the human PCCA cDNA and delivered to newborn mice via an intrahepatic injection. Greater than 64% of the Pcca(-/-) mice were rescued after AAV8-mediated gene transfer and survived until day of life 16 or beyond. Western analysis of liver extracts showed that PCC was completely absent from Pcca(-/-) mice but was restored to greater than wild-type levels after AAV gene therapy. The treated Pcca(-/-) mice also exhibited markedly reduced plasma levels of 2-methylcitrate compared with the untreated Pcca(-/-) mice, which indicates significant PCC enzymatic activity was provided by gene transfer. At the time of this report, the oldest treated Pcca(-/-) mice are over 6 months of age. In summary, AAV gene delivery of PCCA effectively rescues Pcca(-/-) mice from neonatal lethality and substantially ameliorates metabolic markers of the disease. These experiments demonstrate a gene transfer approach using AAV8 that might be used as a treatment for PA, a devastating and often lethal disorder desperately in need of new therapeutic options. 相似文献
8.
9.
Akshay Gopinathan Nair Swathi Kaliki Dilip Kumar Mishra Tarjani Vivek Dave Milind N Naik 《Indian journal of ophthalmology》2015,63(7):620-622
Schwannomas are benign, encapsulated, primary neurilemmal tumors composed of proliferating Schwann cells. Schwannomas are commonly seen in the orbit, but are rare on the epibulbar surface. Herein, we report a case of a 12-year-old boy who presented to us with a slow-growing painless subconjunctival mass in the left eye. There was no intraocular extension of the mass and intra-operatively, the mass could be clearly delineated and was excised off the underlying sclera. Histopathological examination of the mass showed typical features of schwannoma and immunohistochemistry helped to confirm the diagnosis. There was no recurrence of the lesion observed at follow-up 26 months after surgery. Here, we describe this uncommon tumor and review the available literature. Although rare, an epibulbar schwannoma should be considered in the differential diagnosis of an amelanotic, painless subconjunctival nodular mass. Excision of the lesion is the recommended treatment. 相似文献
10.
Haresh T Asnani Vinod C Mehta Akshay Gopinathan Nair Vandana Jain 《Indian journal of ophthalmology》2015,63(6):541-542
Surgical emphysema is defined as gas or air trapped in the subcutaneous tissue plane. Here, we report a rare case of bilateral periorbital and cervicofacial subcutaneous emphysema following a vitreoretinal surgery for inadvertent globe perforation during the administration of peribulbar anesthesia. This condition, although self-resolving when restricted to the subcutaneous plane has the potential to spread into deeper tissue planes such as the retropharyngeal space. The presence of crepitus helps to distinguish it from angioneurotic edema. Ophthalmologists must be sensitive to the fact that surgical emphysema can be a very rare, but possible complication of an intraocular surgery following globe perforation. 相似文献