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目的探讨小儿过敏性紫癜患儿的各种临床特征,以提高对此病的认识。方法2001年1月至2006年1月收集我院小儿过敏性紫癜40例的临床资料进行回顾性分析。结果发病年龄在4~5岁2例,6~14岁38例。发病时间:9月份至次年3月份35例,其他月份少见。主要诱因为感染。40例中都存在皮肤紫癜,双下肢多见,易反复。伴胃肠道症状30例,以脐周痛为主,首发症状易误诊。伴关节症状5例。伴肾脏损害5例,以血尿为主。结论过敏性紫癜是以全身小血管炎症为主要病变,血小板不减少性紫癜,常伴皮肤水肿、荨麻疹、腹痛、关节痛、血尿等症状的疾病。应尽快明确诊断及减少误诊、漏诊。 相似文献
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Objective To discuss a real-time fluorescence quantitative polymerase chain reaction (FQ-PCR) wether if can be used to detect Brucella. Methods According to the BCSP31 gene sequences specific for Brucella, one pair of primers and one TaqMan probe were designed. A real-time PCR was developed with the BCSP31 fragments cloned into PMD18-T vector. The standard cure was established and the sensitivity, the species specificity and the stability of the assay were evaluated. The clinical blood specimens were detected by QT-PCR and compared with clinical diagnosis. Results The standard curve was established with the standard template and the relationship between the Ct and the DNA copy number was linear(r=0.999). The sensitivity of the real-time PCR was 5 copies/μl. The sensitivity of the common PCR was 5×102 copies/μl. The sensitivity was about 100 times higher than common PCR. Species specificity of this FQ-PCR assay evaluated using genomic DNA from 6 Bmcella strains and 5 non-Brucella strains and strong fluorescence was detected in all Brucella strains. The CV of intra-assay and inter-assay reproducibility were 0.71%,7.23%, reprectively. Twenty-four specimens from clinical brucellosis cases, 19 showed positive, the positive coincident rate was 79%(19/24). The negative results were obtained for all 31 negative control, and the negative coincident rate was 100%(31/31). Two were positive from all 30 specimens clinically suspected. Conclusions Highly specific, sensitive, repeatable and coincidental with clinic, this FQ-PCR is quite useful for rapid detection of tiny DNA of Brucella in various samples and laboratory diagnosis. 相似文献
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张宏霞 《临床合理用药杂志》2012,5(7):170-170
人工流产术作为避孕失败后的有效补救措施,在临床上广泛应用。人工流产术简便、安全,但手术信息作为一种应激源,使得选择人工流产术终止妊娠的孕妇易产生焦虑、恐惧、抑郁等心理反应,甚至部分患者因过于紧张而出现恶心、呕吐、面色苍白、头晕、心率减慢、血压下降等人工流产综合征表现及内分 相似文献
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目的建立一种稳定、高自动化的明暗箱,为抗焦虑药物的筛选以及焦虑症病理机制的研究提供自动化检测分析技术。方法采用计算机视频跟踪、图像分析等技术,研制大鼠、小鼠明暗箱图像分析处理系统。并用雄性Wistar大鼠进行明暗环境和指标准确性的验证。结果暗室时间为总时间的79.40%,成功建立明暗环境。运动阈值为18 cm/s时,计算机所获数据与人工记录所获结果具有高度相关性,r0.99。穿箱次数、明室时间、暗室时间、入暗潜伏期的人机相关系数r0.99。与空白组相比,明暗箱模型组穿箱次数、明室时间显著减少。结论明暗箱图像分析处理系统稳定、可靠、自动化程度高、提取信息量大,指标客观灵敏,可推广用于抗焦虑药物的筛选以及焦虑症病理机制的研究。 相似文献
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目的 探讨老年性消化性溃疡的临床诊断及治疗效果.方法 将收治的80例老年消化性溃疡患者,随机分为对照组和观察组各40例.对照组采用奥美拉唑、蒙脱石思密达、替硝唑治疗,观察组采用阿莫西林、克拉霉素及奥美拉唑治疗.分析两组的治疗效果及不良反应发生情况.结果 对照组总有效率85.0%,观察组总有效率90.0%.两组总有效率差异无统计学意义(P<0.05).两组治疗过程中均未见明显不良反应发生.结论 针对老年消化性溃疡的特点,早期诊断,早期治疗,患者预后良好. 相似文献
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目的研究分析孕期健康教育在妇产科门诊护理中的临床应用。方法选取2011年4月~2012年3月在我所妇产科门诊产前检查的312例孕产妇进行研究分析,随机将孕产妇分为观察组(156例)和对照组(156例)。结果对比两组孕产妇自然分娩率以及母乳喂养率,观察组自然分娩率(79.49%)以及母乳喂养率(98.72%)显著优于对照组(41.67%、62.82%),具备统计学意义(P0.05)。结论在妇产科门诊中,护理人员对孕妇实施孕期健康教育可以显著提高孕妇自然分娩率和母乳喂养率,降低并发症的发生率。 相似文献
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