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目的:探讨电针治疗功能性消化不良大鼠海马体NMDA受体的调节机制。方法:本项目采用电针足三里、中脘穴作为干预因素,以功能性消化不良大鼠为受试对象,运用免疫组化等多种技术手段,从边缘系统-脊髓-胃肠多水平研究电针对功能性消化不良大鼠胃肠吸收、胃肠动力及神经递质的影响,探讨电针功能性消化不良大鼠海马体NMDA受体通路的分子机理。结果:电针对功能性消化不良大鼠胃肠吸收功能、胃肠动力等有明显影响,电针对功能性消化不良大鼠海马体NMDA受体有显著调节作用。结论:电针治疗功能性消化不良,可能是通过海马体的NMDA受体通路对认知情感中枢与神经内分泌系统进行良性平衡调节而实现的。这一作用的完成,可能是通过通过拮抗海马NMDA受体,进而纠正海马的"兴奋-抑制"失衡,重建稳态来实现的。 相似文献
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线上教学一直是高等教育教学改革的重点,在慕课、微课、精品在线开放课程等线上教学资源库建设的基础上,线上教学手段和方法更趋于完善,但全面使用线上手段完成教学仍处在尝试阶段.面对特殊的情况,充分利用前期网络资源库,做好教师与学生的角色定位,切实落实完善教学质量的管理和监督,充分开展思政教育,是我校线上教育教学模式变革的新方向.同时,面对教育部提出的"打造金课,淘汰水课"的课程建设口号,我校以线上教学为切入点深挖学科特点,紧密结合专业特色的尝试,更是为探索中医药类金课建设打下了基础. 相似文献
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目的:系统评价整脊及相关疗法治疗椎动脉型颈椎病的疗效。方法:通过全面搜索维普、万方、CNKI等中文数据库中2005至2015年已发表的和近10年间Pub Med中已发表的关于整脊及相关疗法治疗椎动脉型颈椎病的临床随机对照试验的相关文献,并手工查阅关于椎动脉型颈椎病的图书、杂志,运用Cochorane系统评价方法,依据纳入排除标准筛选文献,整理资料。并采用Rev Man5.2软件进行质量评价和Meta分析。结果:共纳入7篇中文文献,共含806例患者。Meta分析结果显示:整脊疗法治疗与对照组相比,综合疗效显示:合并OR(固定效应模型)=6.47,95%CI[3.46,12.10],Z=5.84,P0.00001,具有统计学意义。结论:整脊疗法治疗椎动脉型颈椎病有较好的疗效,同时整脊疗法还能减少疾病复发率,减轻患者症状。但还需要更多高质量、大规模、多中心、规范化的临床随机对照试验进一步验证支持。 相似文献
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Objective
To investigate the protective effect of moxibustion in initiating the endogenous protection information on gastric mucosa, and its relationship with the pathway of common peroneal nerve.Methods
Forty-eight Sprague-Dawley (SD) rats were randomly divided into a normal group (group A), a model group (group B), a moxibustion model group (group C) and a moxibustion model plus surgery group (group D), 12 in each group. Except for group A, rats in the other groups were treated with dehydrated ethanol and aspirin to prepare gastric mucosal damage model. The rats in group B were not treated with any interventions; rats in group C received moxibustion at Zusanli (ST 36), twice a day for continuous 3 d. The rats in group D were subjected to preparing the gastric mucosal damage model after the common peroneal nerve transection, followed by moxibustion at Zusanli (ST 36). After a 3-day intervention, ulcer index (UI) in each group was observed, and the levels of gastric mucosa-related repair cytokines of tumor necrosis factor-α (TNF-α), interleukin-4 (IL-4) and heat shock protein 70 (HSP70) were detected.Results
Compared with group A, the pathological changes and UI of group B were worse (P=0.000), but TNF-α in serum and tissue was changed significantly (P=0.000, P=0.002), IL-4 in serum and tissue was improved significantly (P=0.000, P=0.000). Compared with group B, TNF-α and IL-4 in group C and group D were significantly improved (TNF-α: P=0.003, P=0.016; IL-4: P=0.000, P=0.002). Compared with group C, the changes of UI in group B and group D were poor (both P=0.000); the levels of TNF-α and IL-4 in serum were significantly decreased (TNF-α: P=0.000, P=0.025; IL-4: P=0.000, P=0.034); and tissue HSP70 levels were decreased significantly (P=0.000, P=0.033).Conclusion
Zusanli (ST 36) can transmit information through the pathway of common peroneal nerve, regulate the release of gastric mucosal protective factors, and up-regulate the expression of cytothesis-related proteins, so as to achieve the effect in repairing gastric mucosa.6.
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目的观察穴位埋线法对脾(胃)气虚证家兔血清D-木糖(D-Xylose)及胃泌素(Gastrin,GAS)的影响。方法将32只家兔随机分为4组:空白组、模型组、埋线组、中药组。采用利血平造脾(胃)气虚证模型。观察各组家兔治疗前后血清D-木糖、GAS含量的变化。结果埋线组可升高脾(胃)气虚证家兔血清D-木糖及GAS含量(P〈0.05或P〈0.01),其疗效与中药组相近。结论该疗法能明显改善家兔的脾(胃)气虚证症状体征;该法在治疗脾(胃)气虚证与中药相比诸多指标无差异,但该法操作简便,成本低廉,病人易于接受,值得临床推广。 相似文献
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推拿功法对推拿专业学生体质的影响 总被引:2,自引:0,他引:2
为检验练功对学生体质的影响,我们依据《运动医学》[1]的体格检查方法,设计并检测了推拿专业学生体质情况,以考察练功的作用。1对象与方法1.1对象湖南中医学院1994~1996级推拿专业学生108人。男性98人,女性10人,平均年龄(20.61±0.8... 相似文献
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