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排序方式: 共有1035条查询结果,搜索用时 906 毫秒
1.
Ihsan A. Badr 《International ophthalmology》1993,17(3):155-160
The region is characterized by diversity in cultural, political, economic and health conditions. Blindness in the region varies from 6.4% to 0.2% with cataract ranking highly as an underlying cause. There is a need to develop national policies to deliver affordable, technically suitable, and cost effective management plans to reduce cataract. Economic, demographic, health, and manpower statistics are essential information to be considered in formulating such policies. 相似文献
2.
Ihsan M Kenawi Barsoum N Barsoum Maha A Youssef 《European journal of pharmaceutical sciences》2005,26(3-4):341-348
IR, 1H NMR and mass spectrometric studies showed that cetirizine dihydrochloride interacted strongly with diclofenac sodium, even when the latter was metal bound, forming high molecular weight stable adducts. These new formations were unaffected by the possible steric constraints that may exist because of coordination yet did not have the power to break the formed coordinate bonds. The formed ionic bond took place between the carbonyl ion of diclofenac and the positively charged piperazine ring of cetirizine, forming a ternary compound in the case of the divalent metal clusters (Ca{(dic)2.2H2O}, Mg{(dic)2.2H2O}, Zn{(dic)2.2H2O}) and a quaternary one with the trivalent iron cluster (Fe{dic}3.3H2O). IR bands assigned to nuNH, deltaNH and nuC-N were shifted to lower frequency values in the spectra of the complexes; thus showing that coordination took place at the NH of the diphenylamine. TG and elemental analysis confirmed these results. 相似文献
3.
Cemal Şenyuva Akın Yücel Yagmur Aydın Ihsan Okur Zeki Güzel 《Aesthetic plastic surgery》1997,21(4):233-239
Extracorporeal septoplasty is a radical solution for the severely deviated nose. The major problems associated with this
procedure are fixation of the septal cartilage graft and dorsal irregularities. Extracorporeal septoplasty was performed in
combination with open rhinoplasty in 17 patients with severe nasal deformities. In this technique septum was totally removed
through the columellar incision of open rhinoplasty, corrected outside, and replaced as a free ``L' shaped cartilage graft.
The cartilage graft was fixated to the upper lateral cartilages to restore the natural relations of the anatomical structures.
Additional rhinoplastic manipulations were also performed. The follow-up period was up to 18 months. The overall result was
successful in all patients. Nasal deviation did not recur and secondary revisions were not needed for any patient during follow-up. 相似文献
4.
Bülent Gül Sezer Kulaçoglnu Dr. Muammer Yükse Handan Dogan Ali Ihsan Ökten 《Neurosurgical review》1997,20(1):59-61
Esthesioneuroblastoma is an uncommon malignant neoplasm that arises from olfactory mucosa, often with intracranial extension.A case report of the youngest victim in the literature (2-year-old boy) is presented. 相似文献
5.
Evaluation of flow hemodynamics by color-Doppler following two different brachial arterial repair techniques. 总被引:1,自引:0,他引:1
S Kili? A K Bacako?lu A Y G?ktay M H Ozkan G Erg?r K Bayatli A Gürbüz A Ekin 《European journal of vascular and endovascular surgery》2004,28(3):310-316
OBJECTIVES: We compared the clinical and hemodynamic results following surgical repair of traumatic brachial artery injury using two different techniques micro- and macrovascular repair. MATERIALS AND METHODS: This was a retrospective study of 27 patients who had sustained penetrating, clean cut injuries of the brachial artery. Macrovascular techniques and a saphenous vein graft was used in 13 patients, while 14 patients were treated by primary microsurgical technique. Postoperatively, patients were followed for a mean of 26 months. All patients had color Doppler examination of the brachial artery, digital artery pressures and transcutaneous oxygen saturation determined. RESULTS: Clinical results based on distal pulses, Allens test and digital pressures were similar in the two groups. Color Doppler showed 8/13 anastomotic stenoses in macrovascular vein grafted repairs and 2/14 in microvascular repairs (p<0.05). The ratio of flow velocity proximal compared distal to the injury was significantly decreased in patients who had macrovascular repairs. CONCLUSION: Using ratio between proximal and distal site of anastomosis maximal peak systolic velocity as a objective color Doppler parameter, we were able to demonstrate differences in the hemodynamic status following macrovascular repair with vein grafts and microvascular primary repair. The results emphasize the importance of using a standard repair technique for similar injuries rather than the preference of the surgeon. 相似文献
6.
Dr. Bektaş Açikgöz Mehmet Turgut Osman Ekin Özcan Tunçalp Özgen Beyhan Demirhan Şevket Ruacan 《Lasers in medical science》1992,7(1-4):49-53
In this study we have investigated the negative influence of CO2 and Nd-YAG laser irradiation on rapid cranial regeneration and whether it has any use in certain types of craniosynostosis.
Twenty-two newborn rats were used in the study. Both CO2 and Nd-YAG laser irradiation, which was applied to free bony edges after, suturectomies, resulted in a significant decrease
in skull regeneration. Histopathological examinations revealed severe degeneration caused by both types of laser energies. 相似文献
7.
Several age-related alterations occur at the cellular level in the immune system leading to a decrease in the immune response. The present study was designed to determine the effect of L-carnitine on impaired neutrophil functions of aged rats. For this reason, superoxide anion radical production, chemotaxis and phagocytic activity were studied in the neutrophils obtained from the peripheral blood of young and old rats. We orally gavaged L-carnitine (50 mg/kg b.w. per day) or control vehicle into young (2 months) and aged (24 months) rats for 30 consecutive days. The neutrophils of aged rats exhibited an increase in superoxide anion production and decline in phagocytosis and chemotaxis when compared with that in young rat neutrophils. Superoxide anion production in aged rats was significantly decreased by L-carnitine treatment which was accompanied with a significant enhancement of chemotactic and phagocytic activity being restored to control levels. These findings demonstrated that L-carnitine is capable of restoring the age-related changes of neutrophil functions. 相似文献
8.
Ihsan H. Ciftci Umit Dundar Zafer Cetinkaya Mustafa Kulac Nilay Kiyildi Aycan Turel Deniz Evcik Vural Kavuncu 《Acta parasitologica / Witold Stefański Institute of Parasitology, Warszawa, Poland》2007,52(1):70-73
The objective of this study was to investigate the incidence and density of Demodex folliculorum in the patients with rheumatoid arthritis (RA). Forty-one patients with RA and twenty-seven age and sex matched healthy controls
were enrolled in this study. Disease Activity Score (DAS 28) was used for the assessment of disease activity. Out of 41 patients,
33 were females and 8 males. The mean disease duration was 10.9 ± 8.2 years. The mean DAS 28 was 3.8 ± 1.2. No statistically
significant differences in the incidence and density of Demodex mites were found between patients with RA and controls. Although immunosuppression is thought to be a risk factor for the
D. folliculorum infestation no such correlations could be found in the 41 immunosuppressed patients with RA, therefore, further studies with
larger groups are needed. 相似文献
9.
Ersin Yaris Murat Kesim Mine Kadioglu Nuri Ihsan Kalyoncu Cunay Ulku Rasin Ozyavuz 《Pharmacological research》2003,48(4):335-345
The aim of the present study is to evaluate whether paroxetine (a selective serotonin re-uptake inhibitor) can modify the contractile responses of isolated vas deferens. Some contractile agents, potassium chloride (KCl), adenosine 5'-triphosphate (ATP), noradrenaline (NA), and electrical field stimulation (EFS) caused contractions both in epididymal and prostatic portions of vas deferens. Paroxetine (PX) in concentrations 10(-7) and 10(-6)M potentiated the contractions to KCl and ATP only in epididymal portion but in higher concentrations (10(-5) and 10(-4)M) inhibited the responses in both portions. NA responses were inhibited by PX in all concentrations used, both in prostatic and epididymal portions. Prazosin (PR), an alpha adrenergic receptor blocking agent, inhibited PX-induced potentiation observed for higher concentrations of KCl. PR also inhibited PX-induced potentiation on the responses to ATP in epididymal portion. Pretreatment with PX (10(-7) to 10(-6)M) increased the contractions to EFS but in 10(-5) and 10(-4)M concentrations inhibited them. Even though the preparations were washed out, the inhibited responses of contractile agents could not be restored. After a washout period for PX, when Bay K 8644 (calcium channel activator) was added to the bath medium, the contractile responses to KCl were partially restored. In calcium-free medium, KCl caused contractions in concentrations higher than 80 mM with lower amplitudes which were not affected by PX. Reserpinization did not change the inhibitory pattern of PX's effect on exogenously applied NA in all concentrations tested. In reserpinized rats, the potentiation caused by PX in exogenously applied ATP responses was not observed. In conclusion, we can say that PX has two different effects: inhibition and potentiation of contractions to various agonists. The inhibitory effect of the drug can be explained by a calcium channel blocking activity. The potentiating effect of the drug is mainly related to its presynaptic action, such as NA re-uptake inhibitory effect. 相似文献
10.
Ismail Koramaz Mehmet Ozkan Murat Kesim Kibar Yasar Güven Mine Kadioglu Cunay Ulku Umit Cobanoglu Ersin Yaris Nuri Ihsan Kalyoncu Fahri Ozcan 《Pharmacological research》2005,51(6):567-573
Perioperative spasm of internal mammary artery is a common experience in coronary artery bypass grafting. Many techniques were described of harvesting the internal mammary artery to prevent vasospasm. We investigated the comparison of the contracting and relaxing responses of human internal mammary artery grafts harvested by two different methods. Patients were divided into two groups depending on the harvesting technique. In the first and second groups arteries were harvested by classical and carbon dioxide insufflation techniques, respectively. In both groups, endothelial function of arteries was assessed by precontracting the rings with phenylephrine (10(-5)M) and dilatating them by cumulative acetylcholine (10(-8) to 10(-5)M) concentrations. Cumulative concentration-response curves for phenylephrine (10(-8) to 10(-4)M), noradrenaline (10(-9) to 10(-4)M), and 5-hydroxytryptamine (10(-9) to 10(-4)M) were obtained in all groups. Endothelial integrity of arteries were histopathologically evaluated. In both groups, acetylcholine caused concentration-dependent relaxations in rings precontracted with phenylephrine (10(-5)M). In arteries harvested by carbon dioxide insufflation technique, acetylcholine caused significantly higher relaxations compared to the rings obtained by classical technique (p<0.05). In all rings of study groups, phenylephrine, noradrenaline and 5-hydroxytryptamine caused concentration-dependent contractions. There was not any significant difference in concentration-dependent responses of these contracting pharmacological agents between the groups. Histopathological evaluation revealed no major arterial damage in both groups. Carbon dioxide insufflation technique does seem not only to protect the integrity of the endothelium and the whole vessel, but also prevent the possible vasospasm of the internal mammary artery segments. 相似文献