全文获取类型
收费全文 | 611篇 |
免费 | 93篇 |
国内免费 | 10篇 |
学科分类
医药卫生 | 714篇 |
出版年
2024年 | 1篇 |
2023年 | 6篇 |
2022年 | 2篇 |
2021年 | 7篇 |
2020年 | 4篇 |
2019年 | 9篇 |
2018年 | 14篇 |
2017年 | 10篇 |
2016年 | 15篇 |
2015年 | 20篇 |
2014年 | 26篇 |
2013年 | 26篇 |
2012年 | 14篇 |
2011年 | 14篇 |
2010年 | 15篇 |
2009年 | 28篇 |
2008年 | 18篇 |
2007年 | 31篇 |
2006年 | 17篇 |
2005年 | 18篇 |
2004年 | 23篇 |
2003年 | 19篇 |
2002年 | 19篇 |
2001年 | 21篇 |
2000年 | 15篇 |
1999年 | 26篇 |
1998年 | 29篇 |
1997年 | 23篇 |
1996年 | 28篇 |
1995年 | 18篇 |
1994年 | 25篇 |
1993年 | 16篇 |
1992年 | 10篇 |
1991年 | 13篇 |
1990年 | 15篇 |
1989年 | 16篇 |
1988年 | 17篇 |
1987年 | 17篇 |
1986年 | 14篇 |
1985年 | 12篇 |
1984年 | 6篇 |
1983年 | 8篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 6篇 |
1979年 | 1篇 |
1978年 | 4篇 |
1976年 | 5篇 |
1975年 | 2篇 |
1970年 | 1篇 |
排序方式: 共有714条查询结果,搜索用时 15 毫秒
1.
Fluid role boundaries: exploring the contribution of the advanced nurse practitioner to multi‐professional palliative care 下载免费PDF全文
2.
3.
Directly measured tissue oxygen tension and arterial oxygen tension assess tissue perfusion 总被引:8,自引:0,他引:8
Mean subcutaneous tissue PO2 (PsqO2) measurements were obtained in dogs with an unheated electrode placed in an implanted Silastic tonometer, while PaO2 was increased in increments from 40 to 600 torr during normal, increased, and reduced blood volume. These changes reflect that the mean PsqO2 is approximately 10 torr below the PO2 of venous blood draining that tissue. Since PaO2 was already known, the oxygen content of arterial and venous blood entering and leaving this tissue could be determined by reference to blood-oxygen dissociation curves. Therefore, relative changes in blood flow could be calculated using the Fick principle. After a 20% blood loss, the PsqO2 measured during breathing of room air fell to 20% of baseline, corresponding to an 80% fall in sc blood flow; it remained low until the shed blood was returned despite compensatory changes in cardiac output. Rapid infusion of electrolyte solutions in normovolemic animals produced a temporary increase in local blood flow. Subcutaneous oximetry seems capable of quantifying peripheral perfusion and may be clinically useful. 相似文献
4.
Sendhil K Balasubramanian Ravindranath Tiruvoipati Mohammed Amin Kanakkande K Aabideen Giles J Peek Andrew W Sosnowski Richard K Firmin 《Journal of cardiothoracic surgery》2007,2(1):4-9
Background
Veno-arterial extracorporeal membrane oxygenation (ECMO) is a common modality of circulatory assist device used in children. We assessed the outcome of children who had ECMO following repair of congenital cardiac defects (CCD) and identified the risk factors associated with hospital mortality. 相似文献5.
Peter J. Franks PhD ; Hanne Winterberg RGN DN BSc ; Christine J. Moffatt RGN PhD 《Wound repair and regeneration》2002,10(3):133-140
Little is known of the impact of pressure ulceration on adult patients' health-related quality of life. The purpose of this study was to determine the impact pressure ulceration has on pressure ulcer patients cared for in the community. A case control study design was used by drawing a random sample from patients receiving community nursing care, stratified by the presence of pressure ulceration. In all, 75 patients with pressure ulcers were compared with 100 controls without ulcers using the four-point ulcer grading scale described by United Kingdom consensus guidelines. Patients were interviewed using the Short Form-36 (SF-36) questionnaire and activities of daily living assessed using the modified Barthel scale. Patients with pressure ulcers had significantly poorer physical function (mean difference (d) = 37.6, 95% CI 28.6-46.6, p < 0.001) and social functioning (d = 33.9, 95 % CI 24.0-43.9, p < 0.001) than published age- and sex-matched normative data from the United Kingdom. The difference between cases and controls was much smaller in these domains, with neither approaching statistical significance. After adjustment for age and gender, scores for bodily pain were poorer in patients with no ulceration (d = -10.5, 95% CI - 20.6 to - 0.4, p = 0.042) indicating greater pain in these patients compared with the cases with ulceration. Activities of daily living determined by the modified Barthel scale showed reduced self-care (d = -7.6, 95% CI -12.5 to - 2.7, p = 0.010) and mobility (d = -9.2, 95% CI -14.6 to - 3.8, p = 0.001) in patients with pressure ulceration. The overall ability to perform these activities was also significantly poorer in this group (d = -16.3, 95% CI -27.3 to -5.3, p = 0.004). While patients with pressure ulceration experience some deficits in their health-related quality of life compared with a normal population, these differences are similar to those experienced by other patients receiving community nursing care. 相似文献
6.
7.
Extracorporeal membrane oxygenation with lepirudin anticoagulation for Wegener's granulomatosis with heparin-induced thrombocytopenia 总被引:1,自引:0,他引:1
Balasubramanian SK Tiruvoipati R Chatterjee S Sosnowski A Firmin RK 《ASAIO journal (American Society for Artificial Internal Organs : 1992)》2005,51(4):477-479
Venovenous extracorporeal membrane oxygenation with lepirudin anticoagulation was successfully used for a complicated case of Wegener's granulomatosis and heparin-induced thrombocytopenia. Interestingly, a linear correlation was found between activated partial thromboplastin time and activated clotting time during lepirudin anticoagulation. 相似文献
8.
PJ Hallam P. Mannucci A. Tripodi D. Bevan B. Lawsen L. Tengborn A. Wacey DN Coopel 《Clinical genetics》1998,54(3):231-233
Hallam PJ, Mannucci P, Tripodi A, Bevan D, Laursen B, Tengborn L, Wacey A, Cooper DN. Three novel PROC gene lesions causing protein C deficiency. Clin Genet 1998: 54: 231–233. 0 Munksgaard, 1998
Missense mutations. three of them novel (Am210→Val, Asn248→ Ile, Ah355→Val), were found in the protein c ( PROC ) genes of 7 patients with inherited protein C deficiency associated with venous thrombosis. Comparison with the phenotypic effects of mutations in the analogous residues of factor IX causing hdernophilia B and the use of molecular modelling has provided explanations as to how these lesions might alter either the structure, function or secretion of the protein C molecules encoded. 相似文献
Missense mutations. three of them novel (Am210→Val, Asn248→ Ile, Ah355→Val), were found in the protein c ( PROC ) genes of 7 patients with inherited protein C deficiency associated with venous thrombosis. Comparison with the phenotypic effects of mutations in the analogous residues of factor IX causing hdernophilia B and the use of molecular modelling has provided explanations as to how these lesions might alter either the structure, function or secretion of the protein C molecules encoded. 相似文献
9.
C KAPPAGODA DN SCHELL RM HANSON & P HUTCHINS 《Journal of paediatrics and child health》1998,34(6):508-512
10.