首页 | 官方网站   微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   20976篇
  免费   1214篇
  国内免费   115篇
医药卫生   22305篇
  2023年   164篇
  2022年   127篇
  2021年   772篇
  2020年   391篇
  2019年   749篇
  2018年   848篇
  2017年   486篇
  2016年   507篇
  2015年   590篇
  2014年   805篇
  2013年   1107篇
  2012年   1788篇
  2011年   1695篇
  2010年   975篇
  2009年   903篇
  2008年   1422篇
  2007年   1450篇
  2006年   1355篇
  2005年   1328篇
  2004年   1071篇
  2003年   1019篇
  2002年   946篇
  2001年   116篇
  2000年   64篇
  1999年   118篇
  1998年   105篇
  1997年   109篇
  1996年   89篇
  1995年   125篇
  1994年   106篇
  1993年   87篇
  1992年   67篇
  1991年   70篇
  1990年   46篇
  1989年   39篇
  1988年   43篇
  1987年   37篇
  1986年   41篇
  1985年   44篇
  1984年   45篇
  1983年   23篇
  1982年   28篇
  1981年   37篇
  1980年   26篇
  1979年   34篇
  1978年   33篇
  1977年   20篇
  1976年   29篇
  1975年   20篇
  1974年   22篇
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
Background and objectivesThe treatment of deafferentation pain by spinal DREZotomy is a proven therapeutic option in the literature. In recent years, use of DREZotomy has been relegated to second place due to the emergence of neuromodulation therapies. The objectives of this study are to demonstrate that DREZotomy continues to be an effective and safe treatment and to analyse predictive factors for success.Patients and methodsA retrospective study was conducted of all patients treated in our department with spinal DREZotomy from 1998 to 2018. Bulbar DREZotomy procedures were excluded. A visual analogue scale (VAS) and the reduction of routine medication were used as outcome variables. Demographic, clinical and operative variables were analysed as predictive factors for success.ResultsA total of 27 patients (51.9% female) with a mean age of 53.7 years underwent DREZotomy. The main cause of pain was brachial plexus injury (BPI) (55.6%) followed by neoplasms (18.5%). The mean time of pain evolution was 8.4 years with a mean intensity of 8.7 according to the VAS, even though 63% of the patients had previously received neurostimulation therapy. Favourable outcome (≥ 50% pain reduction in the VAS) was observed in 77.8% of patients during the postoperative period and remained in 59.3% of patients after 22 months average follow-up (mean reduction of 4.9 points). This allowed for a reduction in routine analgesic treatment in 70.4% of them. DREZotomy in BPI-related pain presented a significantly higher success rate (93%) than the other pathologies (41.7%) (p = .001). No association was observed between outcome and age, gender, DREZ technique, duration of pain or previous neurostimulation therapies. There were six neurological complications, four post-operative transient neurological deficits and two permanent deficits.ConclusionDorsal root entry zone surgery is effective and safe for treating patients with deafferentation pain, especially after brachial plexus injury. It can be considered an alternative treatment after failed neurostimulation techniques for pain control. However, its indication should be considered as the first therapeutic option after medical therapy failure due to its good long-term results.  相似文献   
3.
4.
5.
6.
Dambach  Micha  Fieber  Jakob  Wanzenried  Manuel  Fehr  Tobias  Konrad  Christoph  Goertz  Roland  Fieber  David 《Der Anaesthesist》2022,71(11):846-851
Die Anaesthesiologie - Die Anwendung von hohen Sauerstoffkonzentration birgt Gefahren für Patienten und Anwender. Hohe Umgebungskonzentrationen an Sauerstoff bergen die Gefahr von...  相似文献   
7.
8.
9.
10.

Objectives

To determine the incidence of incisional hernia (IH) in the extraction incision (EI) in colorectal resection for cancer. To analyze whether the location of the incision has any relationship with the incidence of hernias and whether mesh could be useful for prevention in high-risk patients.

Methods

Retrospective review of the colon and rectal surgery database from January 2015 to December 2016. Data were classified into 2 groups, transverse (TI) and midline incision (MI), and the latter was divided into 2 subgroups (mesh [MIM] and suture [MIS]). Patients were classified using the HERNIAscore. Hernias were diagnosed by clinical and/or CT examination.

Results

A total of 182 out of 210 surgical patients were included. After a median follow-up of 13.0 months, 39 IH (21.9%) were detected, 23 of which (13.4%) were in the EI; their frequency was lower in the TI group (3.4%) and in the MIM group (5.9%) than in the MIS group (29.5%; p = 0.007). The probability of developing IH in the MIS group showed an OR = 11.7 (95%CI: 3.3-42.0) compared to the TI group and 4.3 (IC 95%: 1.1-16.3) versus the MIM group.

Conclusions

The location of the incision is relevant to avoid incisional hernias. Transverse incisions should be used as the first option. When a midline incision is needed, a prophylactic mesh could be considered in high risk patients because it is safe and associated with low morbidity.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司    京ICP备09084417号-23

京公网安备 11010802026262号