全文获取类型
收费全文 | 336篇 |
免费 | 47篇 |
国内免费 | 2篇 |
学科分类
医药卫生 | 385篇 |
出版年
2023年 | 3篇 |
2022年 | 5篇 |
2021年 | 7篇 |
2020年 | 7篇 |
2019年 | 11篇 |
2018年 | 14篇 |
2017年 | 12篇 |
2016年 | 17篇 |
2015年 | 7篇 |
2014年 | 16篇 |
2013年 | 15篇 |
2012年 | 25篇 |
2011年 | 29篇 |
2010年 | 10篇 |
2009年 | 21篇 |
2008年 | 22篇 |
2007年 | 18篇 |
2006年 | 22篇 |
2005年 | 9篇 |
2004年 | 20篇 |
2003年 | 11篇 |
2002年 | 11篇 |
2001年 | 4篇 |
2000年 | 9篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1996年 | 1篇 |
1992年 | 3篇 |
1991年 | 4篇 |
1990年 | 4篇 |
1989年 | 5篇 |
1988年 | 4篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 2篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 4篇 |
1981年 | 3篇 |
1980年 | 3篇 |
1978年 | 3篇 |
1976年 | 1篇 |
1974年 | 2篇 |
1973年 | 1篇 |
1970年 | 1篇 |
1969年 | 5篇 |
1968年 | 1篇 |
1966年 | 1篇 |
1965年 | 1篇 |
1964年 | 2篇 |
排序方式: 共有385条查询结果,搜索用时 15 毫秒
1.
2.
Fernandez-Arroyabe Naiara García-Meléndez Gaspar De Castro-Almeida Ana Raquel Escalona-Perez Francisca Pérez-Lara Almudena González-Quevedo David García-Quevedo David Tamimi Iskandar 《European journal of orthopaedic surgery & traumatology : orthopedie traumatologie》2022,32(7):1371-1377
European Journal of Orthopaedic Surgery & Traumatology - Proton pump inhibitors (PPIs) are one of the most frequently used drugs worldwide. Previous research has shown that they could increase... 相似文献
3.
Mechleb BK Haddadin TZ Iskandar SB Abboud LN Fahrig SA 《Pacing and clinical electrophysiology : PACE》2006,29(7):791-796
Polymorphic ventricular tachycardia (PVT) is a life-threatening arrhythmia that is typically related to long QT syndrome, organic heart disease, electrolyte abnormalities, cardiotoxic drugs, or adrenergic stimulation. A review of the literature reveals that PVT with normal QT interval and without underlying cause is quite rare. We report a case of idiopathic spontaneous PVT with structurally normal heart and without electrolyte abnormalities, drug reactions, or evidence of catecholamine induced arrhythmia. We also review the literature on the electrocardiographic characteristics and management of idiopathic PVT. 相似文献
4.
Maciej Cabanski Brett Fields Stephanie Boue Natalia Boukharov Hector DeLeon Natalie Dror Marcel Geertz Emmanuel Guedj Anita Iskandar Ulrike Kogel Celine Merg Michael J. Peck Carine Poussin Walter K. Schlage Marja Talikka Nikolai V. Ivanov Julia Hoeng Manuel C. Peitsch 《Inflammation research》2015,64(7):471-486
5.
6.
7.
8.
9.
Sahiratmadja E Baak-Pablo R de Visser AW Alisjahbana B Adnan I van Crevel R Marzuki S van Dissel JT Ottenhoff TH van de Vosse E 《Tuberculosis (Edinburgh, Scotland)》2007,87(4):303-311
Upon infection with mycobacteria the IL-12/IFN-gamma axis plays an essential role in the activation of cell-mediated immunity required for the elimination of pathogens. Mutations in genes of the IL-12/IFN-gamma axis are known to cause extreme susceptibility to infection with environmental mycobacteria, and subtle variations in these genes may influence susceptibility to more virulent mycobacteria. We analyzed the distribution of polymorphisms in four essential genes from the IL-12/IFN-gamma axis, IL12B, IL12RB1, IFNG and IFNGR1, in 382 pulmonary tuberculosis patients and 437 healthy controls from an endemic region in Jakarta, Indonesia. The IL12RB1 gene was sequenced in a subset of individuals. Nine known single nucleotide polymorphisms (SNPs) and two new silent variations, 135G>A and 1056C>T, were detected in IL12RB1. Six functional SNPs (-2C>T, 467G>A, 641A>G, 1312C>T, 1573G>A, 1781G>A) in IL12RB1, an IL12B promoter insertion/deletion polymorphism and CA repeats in IFNG and IFNGR1 were analyzed in the cohort. The IFNGR1 allele CA(12) (p=0.004) and genotype CA(12)/CA(12) (p=0.01; OR 0.5) were associated with protection from pulmonary tuberculosis. Interestingly, IL12B promoter heterozygosity was associated with protection from tuberculosis in BCG-vaccinated individuals (p=0.03; OR=0.6). This new finding supports the role that IL-23-of which IL12B encodes a subunit--plays in generation of memory T cells. 相似文献
10.