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排序方式: 共有424条查询结果,搜索用时 15 毫秒
1.
朱新菊 《世界核心医学期刊文摘》2006,2(5):22-22
肾细胞癌罕见于儿童,通常在儿童晚期被发现。本文报道1例10岁女孩的特殊肾细胞癌。其影像学表现容易导致误诊,但在既往文献中未见报道。因先天性巨输尿管而导致肾皮质变薄,因此当原发性泌尿道上皮疾病(肿瘤或炎性)首次被发现时,肿瘤完全长入排泄腔(临近的输尿管)。萎缩的肾皮质 相似文献
2.
N. Fredj M. Touffahi R. Saidi M. Lefi A. Achour M. Gahbiche C. Hafsa A. Zakhama H. Saad 《The African Journal of Urology》2008,14(1):43-49
Fungus balls as a cause of upper urinary tract obstruction are rare, with less than 60 cases reported in the literature. We herein describe three cases pf secondary anuria caused byCandida infection of the upper urinary tract. The first case was observed in a patient with a transplanted kidney, the second in a diabetic patient and the third in a patient suffering from chronic kidney failure. The treatment consisted of urinary drainage, identification of the infectious organism and appropriate antifungal treatment. 相似文献
3.
Aboubacar Kaba Alain-Jose L Ilunga Ammar Achour Jean-Fran?ois Zagury Charles Chany 《Journal of interferon & cytokine research》2002,22(3):305-310
Sarcolectin (SCL) is a nonspecific stimulator of cellular DNA synthesis that was found in all animal sera tested to date. It inhibits the established interferon (IFN)-dependent antiviral state, restoring cells to their normal status. In this study, we examined the excretion/secretion of the IFN antagonist SCL in sera from healthy donors and in sera collected during different periods of human immunodeficiency virus type 1 (HIV-1) infection. We followed HIV-1-infected patients during all stages of development (seroconversion, initial and advanced phases of AIDS) and found a significant increase in SCL in sera of HIV-infected patients compared with seronegative subjects used as controls. This increase was established during seroconversion, and then the titers leveled off. In the final stage of the disease, the SCL titer increased again very significantly. We attribute this rapid rise to the virus-dependent destruction of T cells that can no longer be repaired. The high SCL level observed at this final stage, which is most predictive of the disease's progression, suggests that the action, rather than the production, of IFN is impaired. 相似文献
4.
Sandberg JK Leandersson AC Devito C Kohleisen B Erfle V Achour A Levi M Schwartz S Kärre K Wahren B Hinkula J 《Virology》2000,273(1):112-119
We investigated the immune response against a human immunodeficiency virus type 1 (HIV-1) nef DNA sequence administered epidermally in mice transgenic for the human major histocompatibility complex (MHC) class I molecule HLA-A201. Ten potential HLA-A2 binding 9-mer Nef peptides were identified by a computer-based search algorithm. By a cell surface MHC class I stabilization assay, four peptides were scored as good binders, whereas two peptides bound weakly to HLA-A2. After DNA immunization, cytotoxic T lymphocyte (CTL) responses were predominantly directed against the Nef 44-52, 81-89, and 85-93 peptides. Interestingly, the 44-52 epitope resides outside the regions of Nef where previously described CTL epitopes are clustered. Dominance among Nef-derived peptides did not strictly correlate with HLA-A2 binding, in that only one of the high-affinity binding peptides was targeted in the CTL response. The 44-52, 85-93, and 139-147 peptides also generated specific CTLs in response to peptide immunization. T helper cell proliferation was detected after stimulation with 20-mer peptides in vitro. Three Nef regions (16-35, 106-125, and 166-185) dominated the T helper cell proliferation. The implications of these results for the development of DNA-based vaccines against HIV is discussed. 相似文献
5.
Epidemiology of sheep pox in Algeria 总被引:1,自引:0,他引:1
Achour HA Bouguedour R 《Revue scientifique et technique (International Office of Epizootics)》1999,18(3):606-617
Sheep pox constitutes a major animal health problem in Algeria, despite the implementation of various national control campaigns over several decades. On the basis of epidemiological data provided by the Veterinary Services of Algeria from 1984 to 1997, the authors performed a statistical survey to determine possible correlations between factors responsible for the persistence of sheep pox, in particular seasonal and climatic variables. The authors propose an explanation for the variations observed and recommend a control programme which would be more appropriate to the agro-pastoral and bioclimatic conditions of the country. 相似文献
6.
Arij Mechergui Wafa Achour Assia Ben Hassen 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2014,122(5):437-442
In the present work, nearly the entire 16S rRNA gene sequences of 46 clinical samples of Neisseria spp. were determined, and the aligned sequences were analyzed to investigate the diversity of 16S rRNA genes in each commensal Neisseria species. Two 16S rRNA types were identified in two Neisseria sicca strains, three 16S rRNA types in five Neisseria macacae strains, fourteen 16S rRNA types in twenty Neisseria flavescens isolates, and fourteen 16S rRNA types in nineteen Neisseria mucosa isolates. The number of nucleotides that were different between 16S rRNA sequences within specie ranged from 1 to 15. We found high intraspecific sequence variation in 16S rRNA genes of Neisseria spp. strains. 相似文献
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Highly active antiretroviral therapy (HAART), although effective in improving the survival of HIV-1-infected individuals, has not been able to reconstitute the adaptive immune response. We have described the use of novel chemical agents to restore T-cell survival/proliferation by inducing cytokine production. Due to its cationic amphiphilic structure, these molecules appear to enhance immune restoration. In this study, we investigated the action of Riluzole (2-amino-6-trifuromethoxybenzothiazole) in HIV-1 infection. Riluzole is able to increase (effective dose from 1 to 1000 nM) the cell-survival of T cells from HIV-1-infected patients and inhibit spontaneous apoptosis. The immunomodulatory effect of riluzole-sensitized cells was ascribed to endogenous type I interferon (IFN) derived from monocytes. Riluzole might be used for restoring the cell survival of immunocompromised patients and eliminating latent infected cells upon HIV-1 reactivation. 相似文献
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