唐山地区3家医院脑梗死二级预防中叶酸的应用现况调查

目的:了解唐山市部分医院脑梗死二级预防中叶酸的应用现状,找到与相关指南之间的差距,为改进脑梗死二级预防工作提供参考。方法:研究对象为唐山市3家医院诊断为脑梗死的住院患者共573例,按照血浆总同型半胱氨酸(tHcy)水平将入选病例分为3组,调查不同组别患者二级预防中叶酸的应用现状。结果:叶酸的使用率在血浆tHcy重度升高组为62.9%,在中度升高组中为50.7%,在轻度升高组中为38.1%,3组间比较差异有统计学意义(P<0.05);但叶酸的使用量3组间比较差异无统计学意义(P>0.05)。结论:唐山地区部分医院对叶酸应用于脑梗死二级预防已经有了一定程度的认识,但使用率、使用量等与相关指南尚有距离,需进一步加强对医务人员的培训。     

用氟尿嘧啶与水杨酸漆剂治疗日光性角化

为了避免5％氟尿嘧啶软膏治疗日光性角化的副作用,作者试用5％氟尿嘧啶分别加5％、8％、10％水杨酸火棉胶漆剂来进行治疗,共治20例,男8,女12。每3周在角化处滴一滴火棉胶剂,脸上的皮损治1～5次,手背的次数要多些,需7～9次才行,原来的角化部脱落,皮肤变软。水杨酸的浓度大小不影响疗效,唯一的副作用是刚上药后可有几分钟灼感。漆剂的成分为弹力火棉胶4克、乙醇30克、乙醚66克。弹力火棉胶的成分为火棉胶97克与蓖麻油3克。疗效是脸部的皮损5人受1次治     

老年痴呆,并非无医可治

中国是世界上老年人口最多的国家。现有60岁以上老年人口9700多万,约占世界老年人口总数的五分之一。到21世纪,预测中国60岁以上人口将超过总人口的10％,将进入老龄化社会。值得注意的是,近年来老年痴呆患者的数量有逐年增加的趋势,在今后若干年内,老年痴呆将成为一个严重的社会问题。 痴呆是一组临床症候群,对此病目     

预防心肌梗死的十项措施

据有关专家统计分析,老年人心肌梗死发病率女性高于男性。女性中以闭经后的妇女心梗发病较多。另外随着年龄的增长,老年合并症如糖尿病、高血脂症等也是引起心梗的危险因素。此外,心肌梗死发病的时间一般在早上6点至下午12点之间,这段时间比其它时间发病的危险高40％,晨间心肌梗死发病率高出全天梗死总数的9％。发生猝死的比例早上危险性比全天高29％。     

HLA ANTIGEN DISTRIBUTION AND HAPLOTYPE SEGREGATION IN CHINESE PATIENTS WITH PSORIASIS

Tissue typing was performed on lymphocytes of 74 unrelated patients and 12 families with multiple affected siblings. HLA-B13, Aw19, B17 (Bw57), Cwl, DRl were found increased. The analysis of haplotype showed that one or two haplotype sharing among affected siblings occurred more frequently than expected (p<0.0001). The result of lods score for 4 families was l.940. These findings suggest that there may be at least one disease gene linked with MHC involved in this disease.     

上海地区1,000例新生儿红细胞G-6-PD缺陷调查

本文报告以高铁血红蛋白(Met-Hb)微量组织化学洗脱法筛选了上海地区1,000例新生儿脐血标本。阳性者并以分光光度法定量测定葡萄糖-6-磷酸脱氢酶(简称G-6-PD)活性为对照。1,000例新生儿红细胞G-6-PD缺陷发病率为0.2％(男、女各1例).该2例临床均无黄疸。家系调查发现,男性患儿之兄亦为G-6-PD缺陷者,目前有核黄疸后遗症。我室亦曾检查87例新生儿高胆红素血症,其中2例为G-6-PD缺陷引起.因此,我们认为上海地区新生儿高胆红素血症病人中,G-6-PD缺陷并非重要原因.     

A NEW METHOD FOR DETERMINATION OF ANTI-DOUBLE STRAND DNA ANTIBODIES TRYPANOSOMA EQUIPERDUM IMMUNOFLUORESCENT METHOD

A new method of determining anti-double strand DNA antibody by blood smears of mice infected with Trypanosoma equiperdum used as a substrate for immunofluorescent technic is described. Sera from 547 persons, including 62 patients with systemic lupus erythematosus (SLE), 68 with other connective tissue diseases (CTD), 288 with miscellaneous diseases, and 129 healthy medical workers and blood donors were determined. The results were all 20 patients with active SLE showed strongly positive reac- tions; only 4 0f 42 patients with inact.ive SLE showed weakly positive react.ions; all other CTD patients except l and all patient.s with miscel- laneous diseases as well as healthy controls showed negative reactions. This test demonstrates very good correla- tion in comparison with the Farr assay and has some advantages over it, such as simplicity of performance, reliability and constancy of results and SLE specificity. seems applicable to the Moreover, the method detection of antinuclear antibody (ANA) under certain conditions. It is of value in diagnosis and follow up of SLE.     

灰黄霉素(Griseofulvin)治疗皮癣菌病(文献综述)

一、概览(6.40.50.)皮癣菌病为广泛流行的皮肤病,其病原菌多为腐物寄生菌,生存、增殖于皮肤的角质、毛发或指(趾)甲等实际上已死亡的组织中。过去对度癣菌病的治疗,一直采用表皮剥脱法,效果不著,许多学者曾致力于寻找各种有效的外用药,有的在试管内有显著的抗菌作用,但在临床上尚无一种药物外用后有足够的     

自制偏光镜配成偏振光显微镜及其应用

偏振光显微镜又名极化显微镜,就是地质工作者所用的矿物显微镜(也称岩石显微镜),在医学检验上也有广泛的用途。它和一般显微镜不同之处主要在于装有两块偏光镜。原装偏振光显微镜价格昂贵(七千至二万元),故应用于医疗单位尚不普遍。作者使用该镜八年来深感有助于病理诊断;新近又自制偏光镜成功,其全部成本不到五角钱,似有介绍推广之价值。     

八十年代前期我国皮肤科的水平和国外的比较

<正> 本文从临床、科研与教学三方面叙述。一、八十年代前期国内皮肤科的水平。我国幅员辽阔,各地情况不一,因此皮肤科的水平也不一致,在农村和中小城市,由于专业人员少,设备简陋,水平较差,在大城市,特别在医学院校的附属医院和皮肤