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1.
Yong Jiang Zhenbang Wei Wenzhou Sun Limeng Liu Zhenkun Huang 《Ceramics International》2021,47(6):7588-7592
Samples in Si–Al-R-O-N (R = Y, Gd, Yb) systems were prepared by solid-state reactions using R2O3, Al2O3, SiO2 and Si3N4 powders as starting materials. X-ray diffraction was done to investigate RAM-J(R) solid solutions [RAM = R4Al2O9, J(R) = R4Si2N2O7] formation and their equilibrium with RSO (R4Si2O10). Phase relations between RAM, J(R) and RSO at 1700 °C were summarized in a phase diagram. It was determined that a limited solid solution of RAM and RSO could be formed along RAM-RSO tie-line, while RAM and J(R) form a continuous solid solution along RAM-J(R) tie-line. In RAM-J(R)-RSO ternary systems, the RAM-J(R) tie-lines were extended towards the RSO corner to form a continuous solid solution area of JRAMss (R = Y, Gd, Yb). The established phase relations in the Si–Al-R-O-N (R = Y, Gd, Yb) systems may facilitate compositional selections for developing JRAMss as monolithic ceramics or for SiC/Si3N4 based composites using the solid-solutions as a second refractory phase. 相似文献
2.
电磁超声换能器一般采用具有超强磁力的稀土永磁制作,在实际检测中由于磁力不可控,存在偏置磁场不够强导致换能效率过低和磁力过强造成操作不方便等问题.提出一种偏置磁场磁力可控的电磁超声换能器,采用电磁铁与永磁铁相结合的方式,达到偏置磁场磁力可控的目的.通过有限元仿真和试验得出,提出的偏置磁场磁力可控的电磁超声换能器,在电磁铁处于关闭模式下,永磁铁能够提供基础磁场;采用增强模式或减弱模式,无被测物时,换能器下表面平均垂直磁通最大分别增强78.58%和减弱19.36%,而提离2 mm检测钢板时,换能器下方钢板表面平均垂直磁通最大分别增强52.99%和减弱38.02%;得出3种模式下,探头磁力随着提离距离缩小而增强的试验曲线;通过增强模式对铝板和钢板进行测厚试验,将检测信号幅值分别提高46.91%和62.01%.所设计的磁力可控电磁超声换能器不仅具有磁力可控的功能,还能够提高检测信号幅值. 相似文献
3.
Ming Zhang Xuefeng Jiang Qicheng Zhang Tao Zheng Mohsen Mohammadniaei Wentao Wang Jian Shen Yi Sun 《Advanced functional materials》2021,31(38):2102274
Immunotherapy is an efficient approach to clinical oncology. However, the immune privilege of the central nervous system (CNS) limits the application of immunotherapeutic strategies for brain cancers, especially glioblastoma (GBM). Tumor resistance to immune checkpoint inhibitors is a further challenge in immunotherapies. To overcome the immunological tolerance of brain tumors, a novel multifunctional nanoparticle (NP) for highly efficient synergetic immunotherapy is reported. The NP contains an anti-PDL1 antibody (aPDL1), upconverting NPs, and the photosensitizer 5-ALA; the surface of the NP is conjugated with the B1R kinin ligand to facilitate transport across the blood-tumor-barrier. Upon irradiation with a 980 nm laser, 5-ALA is transformed into protoporphyrin IX, generating reactive oxygen species. Photodynamic therapy (PDT) further promotes intratumoral infiltration of cytotoxic T lymphocytes and sensitizes tumors to PDL1 blockade therapy. It is demonstrated that combining PDT and aPDL1 can effectively suppress GBM growth in mouse models. The proposed NPs provide a novel and effective strategy for boosting anti-GBM photoimmunotherapy. 相似文献
4.
5.
Shimei Fu Song Xue Jun Chen Shuai Shang Hui Xiao Yu Zang Xuexi Tang 《International journal of molecular sciences》2021,22(4)
The effects of ultraviolet (UV) radiation, particularly UV-B on algae, have become an important issue as human-caused depletion of the protecting ozone layer has been reported. In this study, the effects of different short-term UV-B radiation on the growth, physiology, and metabolism of Porphyra haitanensis were examined. The growth of P. haitanensis decreased, and the bleaching phenomenon occurred in the thalli. The contents of total amino acids, soluble sugar, total protein, and mycosporine-like amino acids (MAAs) increased under different UV-B radiation intensities. The metabolic profiles of P. haitanensis differed between the control and UV-B radiation-treated groups. Most of the differential metabolites in P. haitanensis were significantly upregulated under UV-B exposure. Short-term enhanced UV-B irradiation significantly affected amino acid metabolism, carbohydrate metabolism, glutathione metabolism, and phenylpropane biosynthesis. The contents of phenylalanine, tyrosine, threonine, and serine were increased, suggesting that amino acid metabolism can promote the synthesis of UV-absorbing substances (such as phenols and MAAs) by providing precursor substances. The contents of sucrose, D-glucose-6-phosphate, and beta-D-fructose-6-phosphate were increased, suggesting that carbohydrate metabolism contributes to maintain energy supply for metabolic activity in response to UV-B exposure. Meanwhile, dehydroascorbic acid (DHA) was also significantly upregulated, denoting effective activation of the antioxidant system. To some extent, these results provide metabolic insights into the adaptive response mechanism of P. haitanensis to short-term enhanced UV-B radiation. 相似文献
6.
Yi Qin Tao Xiong Ting Zhao Jianfeng Zhu Jun Yang Yi Liu Xingang Kong Xiaohan Li 《Ceramics International》2021,47(9):12641-12650
The strengthening method of multi-element M-site solid solution is a common approach to improve mechanical properties of MAX phase ceramic. However, the research on capability of multi-element A-site solid solution to improve mechanical properties has rarely been reported. Thereupon, quasi-high-entropy MAX phase ceramic bulks of Ti2(Al1?xAx)C and Ti3(Al1?xAx)C2 (A = Ga, In, Sn, x = 0.2, 0.3, 0.4) were successfully synthesized by in situ vacuum hot pressing via multi-elements solid solution. The multi-elements solid solution in single-atom thick A layer was confirmed by X-ray diffraction and X-ray photoelectron spectroscopy as well as by energy dispersive X-ray spectroscopy mappings. Effects of doped multi-elements contents on the phase, microstructure, mechanical properties, and high temperature tribological behaviors were studied. Results demonstrated that the Vickers hardness, anisotropic flexural strength, fracture toughness, and tribological properties of Ti–Al–C based MAX ceramics could be remarkably improved by constitution of quasi-high-entropy MAX phase in A layers. Moreover, the strengthening and wear mechanisms were also discussed in detail. This method of multi-element solid solution at A-site provides new way to enhance mechanical properties of other MAX phase ceramics. 相似文献
7.
Hiromasa Tanno Emi Kanno Suzuna Sato Yu Asao Mizuki Shimono Shiho Kurosaka Yukari Oikawa Shinyo Ishi Miki Shoji Ko Sato Jun Kasamatsu Tomomitsu Miyasaka Hideki Yamamoto Keiko Ishii Yoshimichi Imai Masahiro Tachi Kazuyoshi Kawakami 《International journal of molecular sciences》2021,22(8)
Chronic infections are considered one of the most severe problems in skin wounds, and bacteria are present in over 90% of chronic wounds. Pseudomonas aeruginosa is frequently isolated from chronic wounds and is thought to be a cause of delayed wound healing. Invariant natural killer T (iNKT) cells, unique lymphocytes with a potent regulatory ability in various inflammatory responses, accelerate the wound healing process. In the present study, we investigated the contribution of iNKT cells in the host defense against P. aeruginosa inoculation at the wound sites. We analyzed the re-epithelialization, bacterial load, accumulation of leukocytes, and production of cytokines and antimicrobial peptides. In iNKT cell–deficient (Jα18KO) mice, re-epithelialization was significantly decreased, and the number of live colonies was significantly increased, when compared with those in wild-type (WT) mice on day 7. IL-17A, and IL-22 production was significantly lower in Jα18KO mice than in WT mice on day 5. Furthermore, the administration of α-galactosylceramide (α-GalCer), a specific activator of iNKT cells, led to enhanced host protection, as shown by reduced bacterial load, and to increased production of IL-22, IL-23, and S100A9 compared that of with WT mice. These results suggest that iNKT cells promote P. aeruginosa clearance during skin wound healing. 相似文献
8.
The organic pollutants in water have been a great environment challenges to human beings, and photocatalytic degradation is an effective method to solve this problem. In this paper, the Rh-loaded cobalt ferrite CoFe2O4 (CFO) nanoparticles have been successfully synthesized by in situ photodeposition of Rh nanoparticles onto the porous CFO particles as the photocatalysts. After incorporating Rh nanoparticles, the CFO/Rh composite has a higher specific surface area and is more efficient in charge separation than the bare CFO. The photocatalytic efficiency of decomposing Malachite Green (MG) is improved from 70% over the bare CFO to 97% over the optimized CFO/Rh in 60 min. The CFO/Rh sample also demonstrates its durability for the degradation of MG in 5 photocatalytic reaction cycles. Additionally, hydroxyl radicals (?OH) and superoxide radicals (?O2?) are proved to be the crucial reactive species during the photocatalytic degradation of MG with CFO/Rh, evidenced by the active species capture experiments. This work provides a useful approach to enhance the photocatalytic activity of semiconductors for degrading organic dyes. 相似文献
9.
Yunyan Liu Ning Jiang Yao Liu Dawei Cui Chang-Feng Yu Huiqiang Liu Zhao Li 《Ceramics International》2021,47(16):22416-22423
Pulsed laser deposition (PLD) was used to prepare tungsten trioxide (WO3) films on ITO substrates with a varying laser power density of 4.0–5.5 W/cm2. XPS indicated that when the laser power density decreased, the peak positions of the W 4f and O 1s orbits shifted slightly to low energy due to the difference in oxygen vacancies. As the laser power density decreased, W6+ gradually replaced the lattice position of O2?, increasing oxygen vacancies in the lattice. The transmittance modulated values (ΔT) were over 44% at 830 nm, indicating strong absorption by the WO3 thin films in the near-infrared ray. The switching time of the WO3 thin films between bleached states and coloured states decreased as the laser power density increased due to the amorphous structure, morphology, and lower oxygen deficiency at a high power density. The high ΔT and very fast switching time of tb (1.09 s) and tc (6.01 s) demonstrated the excellent electrochromic (EC) properties of the WO3 films prepared by PLD. 相似文献
10.
基于电沉积法,针对某铝箔生产企业所产生的高含铝离子废水,通过不同峰值电流密度下形成的电沉积试样的相关电化学曲线测试结果和镀层中的Al质量分数分析,确定所采用电沉积法的最佳峰值电流密度为9 A·dm-2,此时沉积层中铝质量分数为33.21%,原子数量占比为24.69%. 相似文献