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1.
Zaidatul Akmal Othman Zaida Zakaria Joseph Bagi Suleiman Victor Udo Nna Aminah Che Romli Wan Syaheedah Wan Ghazali Mahaneem Mohamed 《International journal of molecular sciences》2021,22(8)
Obesity and hyperlipidemia are major risk factors for developing vascular diseases. Bee bread (BB) has been reported to exhibit some biological actions, including anti-obesity and anti-hyperlipidemic. This study aims to investigate whether bee bread can ameliorate vascular inflammation and impaired vasorelaxation activity through eNOS/NO/cGMP pathway in obese rats. Forty male Sprague-Dawley rats were randomly divided into four groups (n = 10/group), namely: control (normal group), obese rats (OB group), obese rats treated with bee bread (0.5 g/kg/day, OB/BB group) and obese rats treated with orlistat (10 mg/kg/day, OB/OR group). The latter three groups were given a high-fat diet (HFD) for 6 weeks to induced obesity before being administered with their respective treatments for another 6 weeks. After 12 weeks of the total experimental period, rats in the OB group demonstrated significantly higher Lee obesity index, lipid profile (total cholesterol, triglyceride, low-density lipoprotein), aortic proinflammatory markers (tumor necrosis factor-α, nuclear factor-κβ), aortic structural damage and impairment in vasorelaxation response to acetylcholine (ACh). Bee bread significantly ameliorated the obesity-induced vascular damage manifested by improvements in the lipid profile, aortic inflammatory markers, and the impaired vasorelaxation activity by significantly enhancing nitric oxide release, promoting endothelial nitric oxide synthase (eNOS) and cyclic guanosine monophosphate (cGMP) immunoexpression. These findings suggest that the administration of bee bread ameliorates the impaired vasorelaxation response to ACh by improving eNOS/NO/cGMP-signaling pathway in obese rats, suggesting its vascular therapeutic role. 相似文献
2.
M. J. Ghoushji Reza Alebrahim R. Zulkifli A. B. Sulong S. Abdullah C. H. Azhari 《Iranian Polymer Journal》2018,27(8):563-575
Using metallic materials in automotive structures increases weight, fuel consumption and cost, therefore, certain trends have begun to use lightweight and cheaper materials. Fibre composites are used in automotive applications because they are stiff, lightweight and stronger than bulk material, as well as they have a comparable energy-absorbing capacity to that of metallic materials. The aim of this study is to investigate the potentials in natural ramie/bio-epoxy composite in crash energy absorption applications. Cubic specimens consisted of 12, 24 and 30 plies of ramie/bio-epoxy laminates with 50, 80 and 120 mm long which were prepared by hand layup method. Static axial compression load was then applied and the energy-absorbing capability of the ramie/epoxy composite was evaluated. The crashworthiness characteristics of the composite tubes were evaluated by measuring the average and peak crushing load, specific energy absorption, total absorbed energy and crush force efficiency in quasi-static axial compression. The failure mode and behaviour of the tubes were investigated by taking photographs and recording the load–displacement curves during the test accomplishment. The test results indicated that natural ramie/bio-epoxy composite tube has the great potential to be used as an effective energy-absorbing device. 相似文献
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Muhammad Tuseef Asghar Yus Aniza Yusof Mohd Noriznan Mohammad Effendy Yaacob Hasanah Mohd Ghazali Lee Sin Chang Yanty Noorzianna Manaf 《International Journal of Food Science & Technology》2020,55(7):2762-2770
Coconut (Cocos nucifera L.) sugar is a more nutritious alternative sugar source as compared to sugar palm (Borassus flabellifer) and sugarcane (Saccharum officinarum L.). This work was aimed to investigate the browning index (BI), vitamin profile and antioxidant properties of coconut sap sugar syrups, which were produced by different processing methods: rotary evaporation (RE), microwave evaporation (ME) and open-heat evaporation (OHE). The results obtained showed that coconut sugar syrup produced by RE-60 contained high antioxidant activities [DPPH (36.71%) and ABTS (34.84%), TPC (299.87 mg per 100 g sample) and FRAP (3.74 mm )]. These values were slightly lower than those of ME and OHE. Coconut sugar syrup (RE-60) also contained higher amounts of vitamin C (1587.27 mg L−1), vitamin B1 (97.44 mg L−1) and vitamin B3 (19.84 mg L−1) compared with those of ME and OHE coconut sugar syrups. RE-60 was the best method to produce coconut sugar syrup in a shorter time with lower browning index and higher vitamin contents. 相似文献
5.
Tanveer Ahmed Khan Munirah Ezzah Tuan Zakaria Hyun-Joong Kim Suriati Ghazali Saidatul Shima Jamari 《应用聚合物科学杂志》2020,137(8):48396
Recently, the use of controlled release fertilizers in agriculture has resulted in huge benefits in plant growth and cultivation. Superabsorbent polymer (SAP)-coated fertilizers have the added advantage in retaining water in soil after irrigation and also reduce the nutrient release rate from soil in a controlled manner. This study aimed to produce a nitrogen–phosphorus–potassium (NPK) fertilizer coated with superabsorbent carbonaceous microspheres polymer (SPC) by inverse suspension polymerization method with water-retention and controlled release properties. Two sets of experiments were conducted: (1) three different weight percentages and (2) different materials. NPK coated with SPC showed increasing water-retention ability with respect to carbon microsphere percentages and retains >80% water at the 30th day of experiment compared with pure NPK and NPK coated with SAP. The slow release behavior of all samples was investigated by induced coupled plasma mass spectrometry spectrometry and results showed that NPK coated with SAP and SPC has a low release rate with <50% nutrient release compared with uncoated NPK at the 30th day. The release mechanism kinetics of NPK coated with SAP and SPC were studied based on the Kosmeyer–Peppas model. The mechanisms approached Fickian diffusion-controlled release as the n value for both samples was less than 0.5. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020 , 137, 48396. 相似文献
6.
Noor Faeizah Amat Andanastuti Muchtar Muhammad Sufiyan Amril Mariyam Jameelah Ghazali Norziha Yahaya 《Ceramics International》2018,44(6):6409-6416
This work proposes an effective method for dispersion of zirconia suspension for dental block preparation and optimizes the cold isostatic pressing (CIP) pressure to improve the densification of slip-casted zirconia blocks. Two batches of 44 wt% zirconia suspension were prepared using distilled water in a pH 2 medium containing 0.5 wt% polyethyleneimine as dispersant. The first batch was sonicated for different durations (from 5 min to 30 min), and the second batch was dispersed through ball milling at rotational speeds of 200, 300, and 400 rpm for 60, 90, and 120 min. All suspensions were subjected to sedimentation test and particle size measurement. Results revealed that the optimum ultrasonication duration was 10 min, which yielded the smallest particle size of 133 nm. Ball milling at 300 rpm for 120 min achieved the maximum dispersion of particles, with an average size of 75 nm. Under the optimum conditions of ultrasonication duration, ball milling duration, and ball milling speed, the particle size decreased to 48 nm, which is close to the primary particle size. These dispersion techniques and parameters were selected for preparing a suspension to be consolidated into blocks through slip casting and were enhanced through CIP at pressure ranging from 100 MPa to 300 MPa. CIP compaction at 250 MPa significantly increased the shrinkage percentage of green zirconia blocks, with pore radius decreased to 18 nm. The density of zirconia pressed at 250 MPa and presintered at a low temperature of 950 °C was 59% of the theoretical density and was higher than that of commercial presintered blocks. Thus, CIP should be conducted under a compaction pressure of 250 MPa to produce dense and homogeneous zirconia blocks. 相似文献
7.
M.Ahsanul Haque A.Bakar Sulong L.Kee Shyuan E.Herianto Majlan T. Husaini R.Emilia Rosli 《International Journal of Hydrogen Energy》2021,46(5):4339-4353
In this study, the polymer/MWCNT nanocomposites were synthesized from the pristine MWCNT and polymer binders using functionalization with solution processing methods. The synthesized polymer/MWCNT nanocomposites exhibited high specific surface areas than the pristine MWCNT. The MWCNT/Nafion nanocomposite attributed to the maximum peak current at 5.795 × 10?5 (A) while the peak current of MWCNT/PBI was obtained at 3.662 × 10?5 (A). Moreover, polymer/MWCNT based electrocatalysts performed better electrochemical activity because of polymers binders can assist electrochemical interaction using the high surface areas of the catalyst supporting material. Also, the MEAs fabricated using the hot pressing method, while the acid doped PBI membrane sandwiched between the electrodes. The fabricated MEAs were successfully demonstrated in a single cell and found capable of measuring a maximum power density of 112.10 mW/cm2 under 150 °C temperature. In conclusion, the synthesized catalyst-supporting materials enhanced the electrochemical activity and catalyst stability which fulfilling the main objective of this study. 相似文献
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H.A. Mosalman Yazdi N.H. Ramli Sulong 《Journal of Constructional Steel Research》2011,67(10):1435-1441
In this paper, a method based on genetic algorithm is proposed for determining the optimum connection point with the highest lateral buckling load in the Off-Centre bracing system. This type of bracing system is mostly used in seismic areas and it allows architects to have more openings in the panel area. In this system, the non-straight diagonal member introduces eccentricity to the system and is connected to the corner of the frame by a third member. In designing this system, designers often use “trial and error” to locate the connection point of the brace elements considering various parameters affecting the design such as opening and frame dimensions, cross sectional areas of brace elements and the location of the brace element connection. Hence, finding the best connection point with maximum lateral buckling load can be problematic by the conventional methods. To demonstrate the effectiveness of the proposed GA method, examples with different frame specifications were presented. 相似文献
10.
集中空调冷却水变流量问题辨析 总被引:3,自引:0,他引:3
指出集中空调冷却水系统为开式系统,一般不适用功率三次方定律,静压头应为冷却塔塔体扬程,并提出了冷却水泵变速时轴功率的计算公式;明确变流量的节能效果与控制方式密切相关,即使机组处于满负荷状态,但只要是在非设计工况,采用冷凝温度控制法,也可能实现变流量节能;指出制定多台冷水机组部分负荷性能指标的意义。 相似文献