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排序方式: 共有1813条查询结果,搜索用时 140 毫秒
1.
Bandara T. M. W. J. Wickramasinghe H. M. N. Wijayaratne K. DeSilva L. Ajith Perera A. A. I. 《Journal of Materials Science: Materials in Electronics》2021,32(22):26758-26769
Journal of Materials Science: Materials in Electronics - Dye-sensitized solar cells (DSCs) have evolved through the highest devotion of the research community as a low-cost alternative for... 相似文献
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Annette Abraham Ajoe John Kattoor Tom Saldeen 《Critical reviews in food science and nutrition》2019,59(17):2831-2838
AbstractVitamin E is a lipid soluble vitamin comprising of eight natural isoforms, namely, α, β, δ, γ isoforms of tocopherol and α, β, δ, γ isoforms of tocotrienol. Many studies have been performed to elucidate its role in cancer. Until last decade, major focus was on alpha tocopherol and its anticancer effects. However, major clinical trials using alpha-tocopherol like SELECT trial and ATBC trial did not yield meaningful results. Hence there was a shift of focus to gamma-tocopherol, delta-tocopherol and tocotrienol. Unlike alpha-tocopherol, gamma-tocopherol and delta-tocopherol can scavenge reactive nitrogen species in addition to reactive oxygen species. Antiangiogenic effect, inhibition of HMG CoA reductase enzyme and inhibition of NF-κB pathway make the anti-cancer effects of tocotrienols unique compared to other vitamin E isoforms. Preclinical research on non-alpha tocopherol isoforms of vitamin E showed promising data on their anticancer effects. In this review, we deal with the current understanding on the potential mechanisms involved in the anticancer effects of vitamin E and the controversies in this field over last three decades. We also highlight the need to conduct further research on the anticancer effects of non-alpha-tocopherol isoforms in larger population and clinical setting. 相似文献
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Bikash Meher Sanjay Agrawal Rutuparna Panda Lingraj Dora Ajith Abraham 《International journal of imaging systems and technology》2020,30(3):558-576
Recently, the sparse representation (SR) based algorithms have gained much attention from the researchers in the area of image fusion (IF). The building of a compact discriminative dictionary plays a vital role in the sparse-based IF techniques. In this context, an efficient multimodal IF method based on improved dictionary learning is investigated. The key contributions of this paper are: (a) An improved KSVD algorithm is suggested for the dictionary learning process, (b) to reduce the computational time, only the informative patches are selected using energy feature, and (c) a novel region-based fusion scheme is suggested for the first time for the problem on hand. The suggested technique is tested with a number of multimodal images from Harvard Medical School brain database. The results are compared with state-of-the-art multiscale transform-based methods and modified SR-based methods. Unlike earlier methods, our proposed technique generates an adaptive dictionary through selection of informative patches only. This results in a compact dictionary with improved computational efficiency. The experimental results reveal that our approach outperforms other methods. The potential application of the suggested method could be in pathological images for follow-up study and better treatment planning. 相似文献
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Nitsa Buaron Antonella Mangraviti Francesco Volpin Ann Liu Mariangela Pedone Eric Sankey Dina Aranovich Itay Adar Fausto J. Rodriguez Abraham Nyska Riki Goldbart Tamar Traitel Henry Brem Betty Tyler Joseph Kost 《Advanced functional materials》2021,31(44):2100643
Treating neuroinflammation-related injuries and disorders through manipulation of neuroinflammation functions is being heralded as a new therapeutic strategy. In this study, a novel pectic galactan (PG) polysaccharide based gene therapy approach is developed for targeting reactive gliosis in neuroinflammation. Galectin-3 (Gal-3) is a cell protein with a high affinity to β-galactoside sugars and is highly expressed in reactive gliosis. Since PG carries galactans, it can target reactive gliosis via specific carbohydrate interaction between galactan and Gal-3 on the cell membrane, and therefore can be utilized as a carrier for delivering genes to these cells. The carrier is synthesized by modifying quaternary ammonium groups on the PG. The resulting quaternized PG (QPG) is found to form complexes with plasmid DNA with a mean diameter of 100 nm and have the characteristics required for targeted gene therapy. The complexes efficiently condense large amounts of plasmid per particle and successfully bind to Gal-3. The in vivo study shows that the complexes are biocompatible and safe for administration and can selectively transfect reactive glial cells of an induced cortical lesion. The results confirm that this PG-based delivery system is a promising platform for targeting Gal-3 overexpressing neuroinflammation cells for treating neuroinflammation-related injuries and neurodegenerative diseases. 相似文献
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Abraham G. Alvarado Rosaura Hernández-Montelongo Martin Rabelero Lourdes A. Pérez-Carrillo Jorge E. Puig Francisco López-Serrano 《Polymer Engineering and Science》2020,60(2):223-232
A simple but comprehensive model considering homogeneous and micellar nucleation, coagulation, entry of radicals to particles and to micelles and radicals' exit from particles, is presented. The model is validated, in a starved semicontinuous heterophase polymerization of ethyl methacrylate, at three monomer addition rates. The model accurately describes the overall and instantaneous conversion, the average particle density and diameter, and the number and weight average molar masses evolutions over time. It is found that even though the average number of radicals is much smaller than 0.5, the system is not 0-1. An empirical function was used to describe the gel effect. The homogeneous nucleation was the prevailing mechanism for particle formation and large exit rates of radicals were observed. POLYM. ENG. SCI., 60: 223–232, 2019. © 2019 Society of Plastics Engineers 相似文献
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Jiji Abraham Krishnan Sidhardhan Sisanth Ajesh Kulamamvila Zachariah Hanna Joseph Mariya Soney C. George Nandakumar Kalarikkal Sabu Thomas 《应用聚合物科学杂志》2020,137(46):49429
Obtaining strong interfacial interaction between filler and polymer matrix is very crucial for the fabrication of polymer nanocomposites with superior performance. Present study is aimed to fabricate high performance styrene butadiene rubber (SBR) nanocomposites with imidazolium type ionic liquid modified multiwalled carbon nanotube (MWCNT). Ionic liquid facilitates the dispersion of MWCNT in rubber matrix and it is obvious from transmission electron microscopy images. Diffusion of toluene through SBR nanocomposite membranes has been investigated as a function of surface modified MWCNT (f-MWCNT) content to analyze the chain dynamics and filler-polymer interactions. O2 gas barrier effect of nanocomposites with special reference to the filler loading is explored. The substantial improvement in the barrier effect in presence of filler interpreted on the grounds of a theoretical model describing permeability of heterogeneous systems. Finally solvent sensing characteristics of prepared nanocomposites are also analyzed and it is observed that prepared nanocomposites can be used as a flexible solvent sensor. 相似文献