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1.
Social burden caused by paralyzed poliomyelitis was analysed, using data from a Sampling Survey of Handicapped People in China, in 1987. The study results showed: 29.94% of 1707 handicapped polio victims aged 6 or over were not able to go to school; 44.23% of them could not take care of their daily life; 36.32% of them could not play out-door and do shopping; 2.58% of them could not normally communicate with others. 84.53% of the 1487 handicapped victims caused by polio aged 15 or over wholly or partly lost their working ability. We also compared handicapped people's employment rate and the status of marriage with non-handicapped people. Data showed that the employment rate and the number of married handicapped polio victims were remarkably lower then those non-handicapped people. 相似文献
2.
Abnormal hepatic mitochondrial respiration and cytochrome C oxidase activity in rats with long-term copper overload 总被引:2,自引:0,他引:2
RJ Sokol MW Devereaux K O'Brien RA Khandwala JP Loehr 《Canadian Metallurgical Quarterly》1993,105(1):178-187
BACKGROUND: Dietary copper overload in the rat is associated with morphological abnormalities and lipid peroxidation of hepatic mitochondria. This study was designed to determine if copper hepatotoxicity was associated with functional alterations in mitochondrial respiration in conjunction with lipid peroxidation. METHODS: Weanling male rats were pair-fed for 8 weeks on diets containing normal or high levels of copper in combination with sufficient vitamin E. Serum and liver samples were obtained, and hepatic mitochondria were isolated by differential centrifugation. RESULTS: Oxidant injury (decreased levels of hepatic glutathione and alpha tocopherol and increased levels of mitochondrial thiobarbituric acid-reacting substances) was present in the copper-overloaded rats. Serum aminotransferase levels correlated with concentrations of mitochondrial copper and thiobarbituric acid-reacting substances. Copper overload caused a decrease in state 3 respiration and the respiratory control ratio in hepatic mitochondria when several electron donors were used. Analysis of the oxidoreductase activities of the four mitochondrial electron transport protein complexes showed that complex IV (cytochrome C oxidase) activity was reduced by 60% in copper overload. CONCLUSIONS: Functional abnormalities of mitochondria accompany lipid peroxidation and the morphological alterations caused by copper overload, supporting the hypothesis that the mitochondrion is one of the major intracellular targets in copper hepatotoxicity. 相似文献
3.
A. S. Roik A. V. Samsonnikov V. P. Kazimirov V. E. Sokol’skii 《Russian Metallurgy (Metally)》2006,(3):206-211
The structures of Al-Ni melts with 0, 10, 18, 25, 28, 32, 40, 75, 90, and 100 at % Ni are studied by X-ray diffraction. The structural models of the melts, which were analyzed by the Voronoi-Delaunay transformation method, are reconstructed by a procedure that is inverse to the Monte Carlo method using experimental structure-factor curves. The parameters characterizing atomic ordering at short and longer distances are determined to change nonmonotonically in the range 10–40 at % Ni with an extreme in the vicinity of the melt containing 28 at % Ni. In this concentration range, nickel atoms are predominantly located in the pentagonal rings of polytetrahedral clusters of the icosahedral type; these atoms are ~4.1 Å from each other. Such clusters generate a prepeak in the structure-factor curves of the melts in the range 10–40 at % Ni. 相似文献
4.
G. D. Zakumbaeva A. D. Gazizova A. V. Danilov R. I. Egizbaeva D. V. Sokol’skii 《Chemistry and Technology of Fuels and Oils》2007,43(5):408-410
A polyfunctional catalyst for hydrorefining of the catalytic naphtha cut with a high olefin content is proposed. This catalyst
induces isomerization and hydrogenation of olefins on contact with the feedstock with formation of isoparaffins, isomerization
of n-paraffins, hydrotreating to remove sulfur, and other processes. The naphtha obtained satisfies the Euro-4 standard (2005)
with respect to quality.
__________
Translated from Khimiya i Tekhnologiya Topliv i Masel, No. 5, pp. 35–3 6, September–October, 2007. 相似文献
5.
6.
O. N. Fedyaeva A. A. Vostrikov D. Yu. Dubov S. A. Psarov M. Ya. Sokol 《Solid Fuel Chemistry》2007,41(6):323-330
The product composition of the dynamic conversion of brown coal, which was continuously supplied as a water-coal slurry to a flow reactor at 30 MPa, was studied. The temperature of water and coal particles was increased from room temperature to 400°C (top part of the reactor). The conversion of the organic matter of coal was ~48%, and the products collected at the reactor outlet consisted of solid tar components, substances dissolved and emulsified in water, and volatile substances, whose major constituent was CO2. The composition of solid tar components and oils was determined. 相似文献
7.
1. Carnitine esters of erucic acid (22:1 n-9 cis), cetoleic acid (22:1 n-11 cis), brassidic acid (22:1 n-9 trans), gadoleic acid (20:1 n-9 cis) and oleic acid (18:1 n-9 cis) have been compared as mitochondrial substrates and as inhibitors of palmitoylcarnitine oxidation in heart and liver mitochondria. 2. Both the rate of intramitochondrial-CoA acylation and the rate of beta-oxidation decreases as the chain length increases from C18 to C22. There are no significant differences among the three C22 isomers as oxidizable substrates. 3. All the tested acylcarnitines inhibit palmitoylcarnitine oxidation. The C18 and C20 acylcarnitines inhibit by virtue of being competing substrates; i.e. the respiration is not inhibited. The C22-isomers inhibit also respiration; this shows that the inhibition of palmitolycarnitine oxidation is not compensated for by oxidation of C22-acylcarnitines. Brassidoylcarnitine inhibits the oxidation of palmitoylcarnitine and respiration less than erucoyl-and cetoleoylcarnitine. The different behaviour of the C22-isomers is probably due to the difference in their competitive properties with respect to long-chain acyl-CoA dehydrogenase. 4. All C22 acylcarnitines seem to be relatively better oxidized in the liver than in the heart mitochondria while their inhibitory effect on the usage of the radioactive palmitoylcarnitine is very similar. 5. Palmitoylcarnitine inhibits almost completely the "endogenous" formation of acetyl-CoA presumably from malate via pyruvate in the liver mitochondria while the C22-acylcarnitines cause only a partial inhibiton of this acetyl-CaO formation. 相似文献
8.
This paper presents a method to determine soil stiffness properties using measured structural modes of bridges. Normally, the identified mode shapes have to be smoothed. The mode shapes are approximated using functions describing the transverse vibration of distributed–parameter systems. Artificial coefficients are introduced into this solution in order to sum up the error contributions of displacements and its derivatives up to second order. Then, a pier-soil model based on normalized mechanical impedance functions is used. Applying this method along with more than one vertical mode shape leads to acceptable and more accurate results. The amplitudes of pier bottom vibrations are chosen as the suitable weights for the averaging procedure. For the Warth Bridge situated near Vienna, shear wave velocities and shear moduli at the pier foundations have been estimated. The results correspond quite well to the geological investigation. 相似文献
9.
V. A. Avramenko V. I. Sergienko T. A. Sokol’nitskaya 《Theoretical Foundations of Chemical Engineering》2016,50(4):593-597
Some examples of sorption-reagent materials and variants of their application in the practice of treating liquid radioactive waste have been considered. The data on the strontium sorption on samples of a sorption-reagent material under dynamic conditions at different degrees of dilution and different concentrations of seawater have been presented. These data demonstrate that the most efficient practical applications of sorption-reagent materials consist of decontaminating of seawater concentrates of strontium radionuclides. This task is stated during treatment of liquid radioactive waste (LRW) streams at the Fukushima-1 NPP (Japan), where reverse osmosis concentrates constitute the main problem of localization of the aftermath of the disaster that occurred in 2011. 相似文献
10.
The structures of binary Al-TM (transition metal TM = Mn, Co, Ni, Cu) melts at near-liquidus temperatures are studied by X-ray diffraction and simulation using the reverse Monte Carlo method. The melts are found to have chemical local atomic ordering, and this ordering depends on the nature and content of TM. Chemical local atomic ordering leads to a medium-range order as a result of TM atom localization at distances of 0.4–0.5 nm in the composition of polytetrahedral clusters having icosahedral symmetry. A medium-range order in the melts is identified due to the presence of an additional maximum (prepeak) in the left slope of the first peak in experimental structure factor curves. The local atomic orders in the melts and the corresponding crystalline and quasicrystalline phases are found to correlate with each other. 相似文献