泸县6.0级地震文化遗产震害调查与分析

2021年9月16日，四川省泸县发生6.0级地震，对当地的文化遗产造成了不同程度的损坏。为掌握文化遗产在此次地震中的破坏情况，对古建筑、古桥、渡槽、摩崖造像、古遗址以及可移动文物进行震害调查，分析破坏原因，提出不同文化遗产的震害等级，并统计其在此次地震中破坏占比。研究结果表明：古建筑中木结构的震害较轻，砖木结构和石木结构的损伤较为严重，表现为墙体开裂、倾斜、倒塌和屋面损毁等破坏；古桥的桥面板产生裂缝和起壳，桥头堡基石发生移位；摩崖造像发生开裂、石像脱落，部分岩石发生坠落；古遗址的原有缝隙增大，石砌墙歪闪或倾斜；可移动文物与陈列台连接的金属卡件在地震下崩落。根据震害调查结果，将文化遗产的震害划分为4个等级，并对古建筑的维修与加固、摩崖造像的一体化监测、古桥的维护与应急抢险、可移动文物的隔震保护提出几点建议，为我国文化遗产的抗震保护提供参考。     

E7766, a Macrocycle-Bridged Stimulator of Interferon Genes (STING) Agonist with Potent Pan-Genotypic Activity

A strategy for creating potent and pan-genotypic stimulator of interferon genes (STING) agonists is described. Locking a bioactive U-shaped conformation of cyclic dinucleotides by introducing a transannular macrocyclic bridge between the nucleic acid bases leads to a topologically novel macrocycle-bridged STING agonist (MBSA). In addition to substantially enhanced potency, the newly designed MBSAs, exemplified by clinical candidate E7766 , exhibit broad pan-genotypic activity in all major human STING variants. E7766 is shown to have potent antitumor activity with long lasting immune memory response in a mouse liver metastatic tumor model. Two complementary stereoselective synthetic routes to E7766 are also described.     

无黏土相盐水储层钻开液体系构建及其抗污染性能评价

采用NaCl/KCl/HCOONa复配欠饱和盐水作为钻开液的基础液相,自研的聚合物VIS-B作为流型调节剂,可酸溶的改性淀粉STA作为体系的降失水剂,Dua及Jqw作为暂堵材料,构建了一套无黏土相钻开液体系。该体系在密度1.10~1.28 g/cm^3间稳定可调,抗温可达130℃,具有较高的低剪切速率黏度和较好的润滑性能,且能有效抵抗各类储层污染物的污染,满足了Missan油田不同储层段的作业需求。     

Reconstructed Water Oxidation Electrocatalysts: The Impact of Surface Dynamics on Intrinsic Activities

Electroreduction of small molecules such as H₂O, CO₂, and N₂ for producing clean fuels or valuable chemicals provides a sustainable approach to meet the increasing global energy demands and to alleviate the concern on climate change resulting from fossil fuel consumption. On the path to implement this purpose, however, several scientific hurdles remain, one of which is the low energy efficiency due to the sluggish kinetics of the paired oxygen evolution reaction (OER). In response, it is highly desirable to synthesize high-performance and cost-effective OER electrocatalysts. Recent advances have witnessed surface reconstruction engineering as a salient tool to significantly improve the catalytic performance of OER electrocatalysts. In this review, recent progress on the reconstructed OER electrocatalysts and future opportunities are discussed. A brief introduction of the fundamentals of OER and the experimental approaches for generating and characterizing the reconstructed active sites in OER nanocatalysts are given first, followed by an expanded discussion of recent advances on the reconstructed OER electrocatalysts with improved activities, with a particular emphasis on understanding the correlation between surface dynamics and activities. Finally, a prospect for clean future energy communities harnessing surface reconstruction-promoted electrochemical water oxidation will be provided.     

Direct View on the Origin of High Li+ Transfer Impedance in All-Solid-State Battery

Large interfacial resistance plays a dominant role in the performance of all-solid-state lithium-ion batteries. However, the mechanism of interfacial resistance has been under debate. Here, the Li⁺ transport at the interfacial region is investigated to reveal the origin of the high Li⁺ transfer impedance in a LiCoO₂(LCO)/LiPON/Pt all-solid-state battery. Both an unexpected nanocrystalline layer and a structurally disordered transition layer are discovered to be inherent to the LCO/LiPON interface. Under electrochemical conditions, the nanocrystalline layer with insufficient electrochemical stability leads to the introduction of voids during electrochemical cycles, which is the origin of the high Li⁺ transfer impedance at solid electrolyte-electrode interfaces. In addition, at relatively low temperatures, the oxygen vacancies migration in the transition layer results in the formation of Co₃O₄ nanocrystalline layer with nanovoids, which contributes to the high Li⁺ transfer impedance. This work sheds light on the mechanism for the high interfacial resistance and promotes overcoming the interfacial issues in all-solid-state batteries.     

A Skin-Inspired Triboelectric Nanogenerator with an Interpenetrating Structure for Motion Sensing and Energy Harvesting

Rapid advancements in wearable electronics impose the challenge on power supply devices. Herein, a flexible single-electrode triboelectric nanogenerator (SE-TENG) that enables both human motion sensing and biomechanical energy harvesting is reported. The SE-TENG is fabricated by interpenetrating Ag-coated polyethylene terephthalate (PET) nanofibers within a polydimethylsiloxane (PDMS) elastomer. The Ag coating and PDMS are performed as the electrode and dielectric material for the SE-TENG, respectively. The Ag-coated PET nanofibers enlarge the electrode surface area, which is beneficial to increase sensing sensitivity. The flexible SE-TENG sensor shows the capability of outputting alternating electrical signals with an open-circuit voltage up to 50 V and a short-circuit current up to 200 nA in response to externally applied pressure. It is used to sense various types of human motions and harvest electric energy from body motion. The harvested energy can successfully power wearable electronics, such as an electronic watch and light-emitting diode. Therefore, the as-prepared SE-TENG sensor with a pressure response and self-powered capability provides potential applications in wearable sensors or flexible electronics for personal healthcare and human–machine interfaces.     

Matrix Manipulation of Directly-Synthesized PbS Quantum Dot Inks Enabled by Coordination Engineering

The direct-synthesis of conductive PbS quantum dot (QD) ink is facile, scalable, and low-cost, boosting the future commercialization of optoelectronics based on colloidal QDs. However, manipulating the QD matrix structures still is a challenge, which limits the corresponding QD solar cell performance. Here, for the first time a coordination-engineering strategy to finely adjust the matrix thickness around the QDs is presented, in which halogen salts are introduced into the reaction to convert the excessive insulating lead iodide into soluble iodoplumbate species. As a result, the obtained QD film exhibits shrunk insulating shells, leading to higher charge carrier transport and superior surface passivation compared to the control devices. A significantly improved power-conversion efficiency from 10.52% to 12.12% can be achieved after the matrix engineering. Therefore, the work shows high significance in promoting the practical application of directly synthesized PbS QD inks in large-area low-cost optoelectronic devices.     

基于信任链的骚扰电话预判技术研究

当前,骚扰电话乱象屡禁不止,严重影响了人民群众的正常生活,甚至威胁到个人财产安全,因此简单有效地识别骚扰电话技术成为亟待解决的问题。区别于现有的对电话号码进行黑白名单标记、大数据分析等识别方法,提出基于信任链的骚扰电话预判技术,从可信度量的角度计算来电号码的可靠程度,并针对高危受害群体的典型应用场景进行分析,通过对骚扰电话的预判,降低其受到电话骚扰甚至电话诈骗的可能性。