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1.
Patients with ulcerative colitis are usually non- or ex-smokers in contrast to Crohn's disease where smoking is common. Abnormalities of quantity and quality of intestinal mucus have been postulated in the pathogenesis of these diseases. It is possible that smoking habit may exert its effects via changes in mucus in inflammatory bowel disease. We have therefore studied incorporation of N-acetylglucosamine into synthesized colonic mucin in explants from 85 controls with normal colonoscopic appearances and histology, including 27 smokers and 58 nonsmokers, 36 patients with ulcerative colitis and 19 with ileocolonic Crohn's disease over 24 h in tissue culture. Incorporation of N-acetylglucosamine into normal explants was 31.3 +/- (SD) 7.1 dpm/microgram biopsy protein, incorporation was increased in patients with active Crohn's disease (mean 41.2 +/- (SD) 10.4 dpm/microgram biopsy protein, p = 0.003), decreased in inactive ulcerative colitis (mean 24.1 +/- 7.8 dpm/microgram biopsy protein, p = 0.0006) but normal in active ulcerative colitis (mean 35.0 +/- 13.8 dpm/microgram biopsy protein, p = 0.44). No significant relationship was found between cigarette smoking habits and mucus synthesis in controls with normal mucosa (nonsmokers, n = 58, mean 31.0 +/- (SD) 7.52 dpm/microgram biopsy protein; smokers, n = 27, mean 31.8 +/- (SD) 6.1 dpm/microgram biopsy protein, p = 0.9). This study shows that mucus glycoprotein synthesis is reduced in inactive ulcerative colitis, rising to normal levels in active disease and that synthesis is increased in Crohn's disease. There is no effect of smoking on mucus synthesis by control biopsies suggesting that the differences seen in inflammatory bowel disease are not related to cigarette smoking. 相似文献
2.
Raouf Sh. Mikhail Suzy A. Selim Farouk I. Zeidan 《Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)》1976,26(4):191-198
The surface properties of a stannic oxide gel and its thermal dehydration products obtained both in vacuo and in the presence of air in the temperature range 100–600°C have been examined by N2 adsorption. Phase and structural changes have been followed by differential thermal analysis and X-ray diffractometry. Complete pore structure analysis showed that samples dehydrated at or below 250°C were microporous. Above 250°C the pores were found to widen with increase of temperature, the widening occurring concurrently with the crystallisation process. Doping with cations of lower valency (Li+ and Al3+) than the host cation (Sn4+) had little effect on the pore structure and specific surface area for the low temperature samples (≤250°), whereas at higher temperatures, e.g. 600°C, it increased the specific area remarkably. The dope ions produce oxygen vacancies and hinder or retard sintering in SnO2. 相似文献
3.
In the course of their small angle x-ray scattering work, Winslow and Diamond also calculated the radius of gyration of the pores. Using its value for a paste, Diamond adopted two models for the average pore: a sphere and a cylinder of equal height and diameter. This model leads to absurd values for the surface area of the paste. Using a cylindrical model, and the radius of gyration plus the hydraulic radius, the present authors calculated for a similar paste the dimensions of the average pore and obtained the values: . The number of pores per gram of paste was 2.26 × 1017. The paper also discusses the surface area of hardened paste, and points out the extremely important contributions of Winslow and Diamond to the subject. 相似文献
4.
Ayman M. Atta Manar E. Abdel‐Raouf Shimaa M. Elsaeed Abdel‐Azim A. Abdel‐Azim 《应用聚合物科学杂志》2007,103(5):3175-3182
Unsaturated polyester resin (UP) was prepared from glycolyzed oligomer of poly(ethylene terephthalate) (PET) waste based on diethylene glycol (DEG). New diacrylate and dimethacrylate vinyl ester resins prepared from glycolysis of PET with tetraethylene glycol were blended with UP to study the mechanical characteristics of the cured UP. The vinyl ester resins were used as crosslinking agents for unsaturated polyester resin diluted with styrene, using free‐radical initiator and accelerator. The mechanical properties of the cured UP resins were evaluated. The compressive properties of the cured UP/styrene resins in the presence of different vinyl ester concentrations were evaluated. Increasing the vinyl ester content led to a pronounced improvement in the compression strength. The chemical resistances of the cured resins were evaluated through hot water, solvents, acid, and alkali resistance measurements. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 103: 3175–3182, 2007 相似文献
5.
Zhihong Liu Qi Zhang Raouf Boutaba Yaping Liu Baosheng Wang 《Journal of Network and Systems Management》2016,24(4):859-883
Partitioning skew has been shown to be a major issue that can significantly prolong the execution time of MapReduce jobs. Most of the existing off-line heuristics for partitioning skew mitigation are inefficient; they have to wait for the completion of all the map tasks. Some solutions can tackle this problem on-line, but will impose an additional overhead by repartitioning the workload of overloaded tasks. In this paper, we present OPTIMA, an on-line partitioning skew mitigation technique for MapReduce. OPTIMA predicts the workload distribution of reduce tasks at run-time, leverages the deviation detection technique to identify the overloaded tasks and pro-actively adjusts resource allocation for these tasks to reduce their execution time. We provide the upper bound of OPTIMA in time complexity, while allowing OPTIMA to perform totally on-line. Through experiments using both real and synthetic workloads running on an 11-node Hadoop cluster, we have observed OPTIMA can effectively mitigate the partitioning skew and improved the job completion time by up to 36.73 % in our experiments. 相似文献
6.
Carol Fung Jie Zhang Issam Aib Raouf Boutaba 《Journal of Network and Systems Management》2011,19(2):257-277
The accuracy of detecting an intrusion within a network of intrusion detection systems (IDSes) depends on the efficiency of
collaboration between member IDSes. The security itself within this network is an additional concern that needs to be addressed.
In this paper, we present a trust-based framework for secure and effective collaboration within an intrusion detection network
(IDN). In particular, we design a trust model that allows each IDS to evaluate the trustworthiness of other IDSes based on
its personal experience. We also propose an admission control algorithm for the IDS to manage the acquaintances it approaches
for advice about intrusions. We discuss the effectiveness of our approach in protecting the IDN against common attacks. Additionally,
experimental results demonstrate that our system yields significant improvement in detecting intrusions. The trust model further
improves the robustness of the collaborative system against malicious attacks. The experimental results also support that
our admission control algorithm is effective and fair, and creates incentives for collaboration. 相似文献
7.
In this paper, we propose a new approach that guarantees the stability and robustness of an adaptive control law of a nonlinear system.The control diagram proposed contains a Takagi–Sugeno–Kang fuzzy controller (TSK-FC) and a training block allowing the online adaptation of the FC parameters. The adaptation algorithm used is based on the gradient with minimization of the quadratic error between the system output and that desired by using the direct method of Lyapunov. However, our approach considers the gradient step of each adaptive FC parameter to be bound. This approach was applied to the control of an inverted pendulum. The results obtained confirm well the validity of such an adaptation especially the guarantee of the pendulum stability and the robustness of its control with respect to the disturbances introduced on the FC parameters and the pendulum itself. 相似文献
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10.
Raouf Boutaba Wojciech Golab Youssef Iraqi Tianshu Li Bill St. Arnaud 《Journal of Grid Computing》2003,1(4):387-394
Grid applications call for high performance networking support. One attractive solution is to deploy Grids over optical networks. However, resource management in optical domains is traditionally very rigid and cannot successfully meet the requirements of Grid applications, such as flexible provisioning and configuration. In this paper, we present a customizable resource management solution for optical networks where users can create lightpaths on demand and manage their own network resources. Thanks to a Grid-centric system architecture, lightpath resources can be shared among users and easily integrated with data and computation Grids. 相似文献