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1.
Molecular Ordering: Selectivity of Threefold Symmetry in Epitaxial Alignment of Liquid Crystal Molecules on Macroscale Single‐Crystal Graphene (Adv. Mater. 40/2018) 下载免费PDF全文
2.
Sharat Chandra Barman Md. Abu Zahed Md. Sharifuzzaman Seok Gyu Ko Hyosang Yoon Joong San Nah Xing Xuan Jae Yeong Park 《Advanced functional materials》2020,30(14)
Current immunosensors have an insufficient number of binding sites for the recognition of biomolecules, which leads to false positive or negative results. In this research, a facile, cost‐effective, disposable, and highly selective electrochemical immunosensing platform is developed based on cationic polyelectrolyte polyallylamine (PAAMI) anchored laser‐ablated graphene (LAG). Here, for the first time, PAAMI is introduced to stabilize LAG flakes, while retaining the intrinsic thermal and electronic properties of the substrate by noncovalent π–π interaction and electrostatic physical absorption. The sensing platform offers a suitable number of anchoring sites for the immobilized antibodies by providing ? NH2 functional groups. The proper grafting of PAAMI is confirmed through X‐ray photoelectron spectroscopy and Raman spectroscopy. The immunosensing platform is applied to detect immunoglobulin (IgG) biomarkers as a proof of concept. Under optimized conditions, the sensing platform exhibits a linear range of 0.012–15 and 15–352 ng mL?1 with a limit of detection of 6 pg mL?1 for IgG detection with high selectivity. Based on the analysis, the developed immunosensing platform can be used for point‐of‐care detection of IgG in clinical diagnostic centers. Furthermore, the developed strategy is well suited for the detection of other cancer biomarkers after immobilizing the relevant antibodies. 相似文献
3.
Multimedia Tools and Applications - In the area of smart farming, a big data is being created using information and communication technologies such as the Internet of Things and Cloud computing.... 相似文献
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5.
Novel reddish-orange-emitting Ca2GdNbO6:Sm3+ phosphors based on the emission of 4G5/2 → 6H9/2 transition at 651 nm with the chromatic coordinate of (0.633, 0.366) were synthesized. The crystal structure and chemical purity were identified in detail. Under the 407 nm excitation, the optimum concentration of Sm3+ ion was found to be 5 mol% dominated by the dipole-dipole interaction in the Ca2GdNbO6 host material. The color purity of the sample with optimum doping was estimated to be about 78.38%. Besides, the thermal stability was also studied, and it was further found that the emission intensity remained 65.32% at 423 K. The packaged white LED device exhibited excellent CRI and CCT values of 92.43 and 4896 K. Finally, the polydimethylsiloxane film with a stable structure and flexible property was prepared. These above results reveal that novel reddish-orange-emitting Ca2GdNbO6:Sm3+ phosphors can be applied in high CRI white communication and flexible display applications. 相似文献
6.
Dr. Ala Jo Mingi Kim Dr. Jong In Kim Jaeyoung Ha Yoon Soo Hwang Hyunsung Nam Dr. Injae Hwang Dr. Jae Bum Kim Prof. Seung Bum Park 《ChemMedChem》2021,16(7):1104-1115
Obesity has become a pandemic that threatens the quality of life and discovering novel therapeutic agents that can reverse obesity and obesity-related metabolic disorders are necessary. Here, we aimed to identify new anti-obesity agents using a phenotype-based approach. We performed image-based high-content screening with a fluorogenic bioprobe (SF44), which visualizes cellular lipid droplets (LDs), to identify initial hit compounds. A structure-activity relationship study led us to yield a bioactive compound SB1501, which reduces cellular LDs in 3T3-L1 adipocytes without cytotoxicity. SB1501 induced the expression of gene products that regulate mitochondrial biogenesis and fatty acid oxidation in 3T3-L1 adipocytes. Daily treatment with SB1501 improved the metabolic states of db/db mice by reducing body fat mass, adipose tissue mass, food intake, and increasing glucose tolerance. The anti-obesity effect of SB1501 may result from perturbation of the PGC-1α–UCP1 regulatory axis in inguinal white adipose tissue and brown adipose tissue. These data suggest the therapeutic potential of SB1501 as an anti-obesity agent via modulating mitochondrial activities. 相似文献
7.
Sudong Chae Seungbae Oh Kyung Hwan Choi Jin Woong Lee Jiho Jeon Zhixiang Liu Cong Wang Chaeheon Woo Liyi Shi Joohoon Kang Si Young Song Sung Jae Kim Jung Heon Lee Hak Ki Yu Jae-Young Choi 《Ceramics International》2021,47(9):11935-11941
To achieve the stable dispersion of 1D van der Waals crystal Mo6S3I6 in aqueous media, the tri-block copolymer (Poloxamer) is used as dispersant. The head group of Poloxamer, hydrophobic polypropylene oxide parts can be adsorbed to Mo6S3I6 surface by hydrophobic interaction and the tail group with hydrophilic polyethylene oxide exposed to the outside of the Mo6S3I6 is soluble in water and can form sufficient steric hindrance, resulting in stable aqueous dispersion in nm scale. The excellent biocompatibility of aqueous dispersed nm scale 1D Mo6S3I6 was demonstrated by effective proliferation of C2C12 cells. 相似文献
8.
Sang-Chae Jeon Jae-Won Lee Joo-Young Yoon Yung-Zun Cho Dong-Joo Kim Dong Seok Kim Keon Sik Kim Jong Hun Kim Jae Ho Yang 《Ceramics International》2019,45(6):6863-6868
A reduction process in the head-end for pyroprocessing has been adopted to avoid oxidation attack on the molybdenum crucible during sintering. The reduction process is employed to reduce U3O8 pellets to UO2 prior to sintering. This allows elimination of the oxygen source, which causes oxidation attack during sintering, thereby permitting the use of a metallic crucible. However, little densification occurs due to the low reduction temperature limited by the INCONEL crucible. Consequently, the amount of material scraps from the pellets increases, thus creating an additional processing burden due to its high radioactivity. To reduce the amount of scraps, densification should be enhanced. This study suggests a simple atmospheric control strategy and clarifies its effects. With the atmospheric control, a higher bulk density and better attrition resistance were obtained in comparison to without this strategy. This can be explained in terms of O/U ratio dependent diffusion kinetics during the reduction of U3O8 to UO2. 相似文献
9.
Shin Dong Hwan Kim Dae Yun Choi Chang Kyoung Lee Seong Hyuk 《Journal of Mechanical Science and Technology》2019,33(2):967-971
Journal of Mechanical Science and Technology - Confocal fringe patterns of evaporating sessile drops have provided initial evidence of the presence of a sub-micron thin liquid film emanating from... 相似文献
10.
Metallurgical and Materials Transactions B - We developed a simulation model to predict inclusion transformation during the solidification of steel by linking the Ohnaka model with the FactSage... 相似文献