Electrospun Zn-doped Ga2O3 nanofibers and their application in photodegrading rhodamine B dye

Ultrawide band gap semiconductor materials have attracted considerable attention in recent years owing to their great potential in the photocatalytic field. In this study, Zn-doped Ga₂O₃ nanofibers with various concentrations were synthesized via electrospinning; they exhibited a superior photocatalytic degradation performance of rhodamine B dye compared to that of undoped Ga₂O₃ nanofibers. The Zn dopant replaced Ga sites via replacement doping, which could increase the concentration of oxygen vacancies and lead to enhanced photocatalytic properties. When the Zn concentration increased, a Ga₂O₃/ZnGa₂O₄ hybrid structure formed, which could further enhance the photocatalytic performance. The separation of photogenerated carriers due to Zn doping and heterojunctions were the primary causes of the enhanced photocatalytic performance. This study provides experimental data for the fabrication of high-performance photocatalysts based on Ga₂O₃ nanomaterials.     

Achieving fabrication of highly transparent Y2O3 ceramics via air pre-sintering by deionization treatment of suspension

An easy albeit quite effective deionization suspension treatment was adopted to alleviate the detrimental effects related to the hydrolysis of Y₂O₃ in an aqueous medium. Fabrication of highly transparent Y₂O₃ ceramics with a fine grain size via air pre-sintering and post–hot isostatic pressing (HIP) treatment without using any sintering additive was achieved using the treated suspensions. The hydrolysis issue of Y₂O₃ powder in an aqueous medium was effectively alleviated by using deionization treatment, and a well-dispersed suspension with a low concentration of dissolved Y³⁺ species was obtained. The dispersed suspensions were consolidated by the centrifugal casting method, and the green bodies derived from the suspension of 35.0 vol% solid loading showed an improved homogeneity with a relative density of 52.1%. Fully dense Y₂O₃ transparent ceramic with high transparency was obtained by pre-sintering consolidated green compacts at a low temperature of 1400°C for 16 h in air followed by a post-HIP treatment at 1550°C for 2 h under 200 MPa pressure. The sample had a fine average grain size of 690 nm. The in-line transmittance of the sample reached 83.3% and 81.8% at 1100 nm and 800 nm, respectively, very close to the theoretical values of Y₂O₃.     

A Potent,Selective CBX2 Chromodomain Ligand and Its Cellular Activity During Prostate Cancer Neuroendocrine Differentiation

Polycomb group (PcG) proteins are epigenetic regulators that facilitate both embryonic development and cancer progression. PcG proteins form Polycomb repressive complexes 1 and 2 (PRC1 and PRC2). PRC2 trimethylates histone H3 lysine 27 (H3K27me3), a histone mark recognized by the N-terminal chromodomain (ChD) of the CBX subunit of canonical PRC1. There are five PcG CBX paralogs in humans. CBX2 in particular is upregulated in a variety of cancers, particularly in advanced prostate cancers. Using CBX2 inhibitors to understand and target CBX2 in prostate cancer is highly desirable; however, high structural similarity among the CBX ChDs has been challenging for developing selective CBX ChD inhibitors. Here, we utilize selections of focused DNA encoded libraries (DELs) for the discovery of a selective CBX2 chromodomain probe, SW2_152F. SW2_152F binds to CBX2 ChD with a K_d of 80 nM and displays 24-1000-fold selectivity for CBX2 ChD over other CBX paralogs in vitro. SW2_152F is cell permeable, selectively inhibits CBX2 chromatin binding in cells, and blocks neuroendocrine differentiation of prostate cancer cell lines in response to androgen deprivation.     

Colorimetric quantification of aqueous hydrogen peroxide in the DC plasma-liquid system

The quantification of hydrogen peroxide(H_2O_2) generated in the plasma-liquid interactions is of great importance, since the H_2O_2 species is vital for the applications of the plasma-liquid system.Herein, we report on in situ quantification of the aqueous H_2O_2(H_2O_2 aq) using a colorimetric method for the DC plasma-liquid systems with liquid as either a cathode or an anode. The results show that the H_2O_2 aqyield is 8–12 times larger when the liquid acts as a cathode than when the liquid acts as an anode. The conversion rate of the gaseous OH radicals to H_2O_2 aqis 4–6 times greater in the former case. However, the concentrations of dissolved OH radicals for both liquid as cathode and anode are of the same order of tens of n M.     

低透气性煤层瓦斯综合抽采及利用模式探索

为了解决平煤股份八矿瓦斯突出问题，结合自身多年经验，探索出了适合平煤八矿的低透气性煤层瓦斯综合抽采及利用模式。通过“运输巷底抽巷+穿层钻孔”掩护运输巷顺利掘进，在工作面两巷道施工完毕后，从两巷施工本煤层钻孔抽采工作面煤层瓦斯。由于本煤层钻孔轨迹难以控制，容易导致工作面中间出现空白带，因此通过“采面中间底抽巷+穿层钻孔”进一步消除采面中间的突出危险性；开发了本煤层钻孔和穿层钻孔的封孔工艺，满足了瓦斯高浓度抽采。瓦斯抽采保障了发电机组的顺利发电，瓦斯发电量逐年上升；瓦斯抽采和发电利用相互促进，形成了良性循环。     

深锥形槽体对细粒煤干扰沉降分级实验研究

本文重点研究了自制深锥形干扰沉降分级机在不同影响因素下对细粒煤的分级效率,结果表明:底部和中部同时给水形式的设计有利于细粒煤分级,底部与中部给水量比值对分级效率有一定影响但不明显;给料速度及浓度值越低,细粒煤分级效率越高。该装置的适宜分级条件为流量配比2∶1、给料速度0.50m/s、矿浆浓度40%时,粒级级配(0.25~0.125mm和1.0~0.5mm)分级效率接近65%,较常规分级旋流器分级效率50%~60%提高约5%~15%,实验结果表明深锥形干扰沉降分级机可有效实现细粒煤的分级。