全文获取类型
收费全文 | 982篇 |
免费 | 103篇 |
国内免费 | 2篇 |
学科分类
工业技术 | 1087篇 |
出版年
2024年 | 1篇 |
2023年 | 12篇 |
2022年 | 11篇 |
2021年 | 46篇 |
2020年 | 24篇 |
2019年 | 51篇 |
2018年 | 48篇 |
2017年 | 44篇 |
2016年 | 43篇 |
2015年 | 36篇 |
2014年 | 59篇 |
2013年 | 70篇 |
2012年 | 83篇 |
2011年 | 95篇 |
2010年 | 59篇 |
2009年 | 57篇 |
2008年 | 55篇 |
2007年 | 59篇 |
2006年 | 49篇 |
2005年 | 31篇 |
2004年 | 22篇 |
2003年 | 27篇 |
2002年 | 26篇 |
2001年 | 16篇 |
2000年 | 3篇 |
1999年 | 2篇 |
1998年 | 12篇 |
1997年 | 10篇 |
1996年 | 7篇 |
1995年 | 2篇 |
1994年 | 2篇 |
1993年 | 2篇 |
1992年 | 1篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1988年 | 1篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1983年 | 3篇 |
1978年 | 1篇 |
1976年 | 3篇 |
1973年 | 3篇 |
1971年 | 1篇 |
排序方式: 共有1087条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Pedro Lavrador Marco R. Esteves Vítor M. Gaspar João F. Mano 《Advanced functional materials》2021,31(8):2005941
The complex tissue-specific physiology that is orchestrated from the nano- to the macroscale, in conjugation with the dynamic biophysical/biochemical stimuli underlying biological processes, has inspired the design of sophisticated hydrogels and nanoparticle systems exhibiting stimuli-responsive features. Recently, hydrogels and nanoparticles have been combined in advanced nanocomposite hybrid platforms expanding their range of biomedical applications. The ease and flexibility of attaining modular nanocomposite hydrogel constructs by selecting different classes of nanomaterials/hydrogels, or tuning nanoparticle-hydrogel physicochemical interactions widely expands the range of attainable properties to levels beyond those of traditional platforms. This review showcases the intrinsic ability of hybrid constructs to react to external or internal/physiological stimuli in the scope of developing sophisticated and intelligent systems with application-oriented features. Moreover, nanoparticle-hydrogel platforms are overviewed in the context of encoding stimuli-responsive cascades that recapitulate signaling interplays present in native biosystems. Collectively, recent breakthroughs in the design of stimuli-responsive nanocomposite hydrogels improve their potential for operating as advanced systems in different biomedical applications that benefit from tailored single or multi-responsiveness. 相似文献
5.
6.
Romero Yesa Susana Aláez-Martínez Marian Ferran Zubillaga Ane García-Olalla Ana 《Universal Access in the Information Society》2021,20(3):573-593
Universal Access in the Information Society - This study focuses on a case study developed at a higher education institution, which comprises developing a new virtual teaching unit (VTU) aimed at... 相似文献
7.
Tamara G. Oberti Diego Larsen M. Susana Cortizo 《Polymer-Plastics Technology and Engineering》2019,58(4):443-453
New copolymers of dioctyl fumarate (DOF) and styrene (S) were synthetized by radical polymerization and used to modify bitumen. The poly(dioctyl fumarate-co-styrene) copolymers, PFS, were characterized by 1H-NMR and FTIR spectroscopies and size exclusion chromatography (SEC) in order to determine their monomer composition and weight average molecular weights, respectively. The polymer-bitumen blending conditions were optimized and the samples analyzed by different methodologies. Fluorescence microscopy, rotational viscosity and differential scanning calorimetry (DSC) were used to study the morphological changes of blends during their manufacturing and the rheological and thermal behavior, respectively. All modified bitumen (MB) exhibited higher viscosity than the based bitumen (BB) under studied conditions and this effect was more evident for the MB containing the higher molecular weight polymer. The addition of polymers to BB enhances the bitumen viscosity and thus increased the energy required for the flowing (activation energy calculated by Arrhenius equation). Thermal and morphological analysis showed that all MB exhibited good polymer- bitumen compatibility, which could be consider as a good starting point for a potential applications of this new material in road engineering. 相似文献
8.
Anabela Santos Ângelo Luís Susana Ferreira Ana P. Duarte 《International Journal of Food Science & Technology》2019,54(3):862-870
In this work, heather and its flowers were studied regarding their antioxidant and antimicrobial activities. Plants were subjected to ultrasound-assisted methanolic extraction followed by fractionation. A phytochemical characterisation of extracts content in total phenols and flavonoids, and their antioxidant activity was performed. The antimicrobial activity was evaluated through the determination of minimum inhibitory concentration and by bioautography. Following, studies on the antilisterial potential were carried out by: time-kill curves, inhibition of biofilm formation and tolerance of Listeria monocytogenes to adverse conditions. The results evidenced the antioxidant activity in both extracts, as well as, the antimicrobial activity against Gram-positive bacteria. Concerning the evaluation of the antilisterial potential, a bacteriostatic behaviour and inhibition of biofilms formation ability were observed. Listeria monocytogenes showed an increased susceptibility to adverse conditions when preincubated with extracts. Thus, heather and its flowers may be a source of new compounds with antilisterial activity potential. 相似文献
9.
Brito Claúdia Esteves Marisa Peixoto Hugo Abelha António Machado José 《Wireless Networks》2022,28(3):1269-1277
Wireless Networks - Continuous ambulatory peritoneal dialysis (CAPD) is a treatment used by patients in the end-stage of chronic kidney diseases. Those patients need to be monitored using blood... 相似文献
10.
Lauane G. Moreno Paulo H. Evangelista-Silva Edivânia C. Santos Rodrigo P. Prates Artenizia C. Lima Mateus F. Mendes Vinícius O. Ottone Marcelo H. F. Ottoni Wagner F. Pereira Gustavo E. B. A. Melo Elizabethe A. Esteves 《European Journal of Lipid Science and Technology》2021,123(9):2000332
Inflammatory bowel diseases (IBD) affect the gastrointestinal tract, and the imbalance of intestinal immune homeostasis can trigger them. Pequi oil (PO), a monounsaturated (MUFA) and carotenoid-rich food with nutraceutical potential, could help reshape the intestinal immune response, ameliorating IBD outcomes. This study investigates the effects of a 28 days intake of PO on elements of the intestinal immune response of mice with DSS-induced ulcerative colitis (disease activity index, colonic damage, inflammatory cells and markers). PO reduces body weight, colonic crypt and goblet cell losses and ameliorates diarrhea. In the colon, it increases γδT cells and secretory-IgA and decreases CD8+T cells. In lymphoid organs, it reduces CD8+T cells. Moreover, it also reduces the IL-17 and CRP in plasma. PO oil promotes a less cytotoxic response that may protect mice from immunological injuries caused by an IBD in the intestinal mucosa, improving the disease prognosis. Practical applications: This study demonstrates that the intake of pequi oil contributes to the regulation of immune response and improves clinical and histological signs of DSS-induced ulcerative colitis in mice. Its effects in cytotoxic cell reduction and other inflammatory markers and stimulation of regulatory cells, and preservation of mucus-producing cells, provide news insights about the importance of the regular intake of this food to better prognosis of ulcerative colitis acute episodes. In addition, these findings encourage further studies with foods with a protective potential for the intestinal mucosa. 相似文献