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排序方式: 共有126条查询结果,搜索用时 15 毫秒
1.
Alfredo M. Gravagnuolo Eden Morales‐Narváez Charlene Regina Santos Matos Sara Longobardi Paola Giardina Arben Merkoçi 《Advanced functional materials》2015,25(38):6084-6092
Class I hydrophobin Vmh2, a peculiar surface active and versatile fungal protein, is known to self‐assemble into chemically stable amphiphilic films, to be able to change wettability of surfaces, and to strongly adsorb other proteins. Herein, a fast, highly homogeneous and efficient glass functionalization by spontaneous self‐assembling of Vmh2 at liquid–solid interfaces is achieved (in 2 min). The Vmh2‐coated glass slides are proven to immobilize not only proteins but also nanomaterials such as graphene oxide (GO) and quantum dots (QDs). As models, bovine serum albumin labeled with Alexa 555 fluorophore, anti‐immunoglobulin G antibodies, and cadmium telluride QDs are patterned in a microarray fashion in order to demonstrate functionality, reproducibility, and versatility of the proposed substrate. Additionally, a GO layer is effectively and homogeneously self‐assembled onto the studied functionalized surface. This approach offers a quick and simple alternative to immobilize nanomaterials and proteins, which is appealing for new bioanalytical and nanobioenabled applications. 相似文献
2.
This study investigates the citation patterns in the journal, Medical Principles and Practice from its inception in 1989 through 2000 (volumes 1-9). The data set includes 4740 references appended to the 221 original
research articles. All of the citations were entered into a ProCite database for analysis. Specifically, this study addresses:
(1) bibliometric patterns of cited works in terms of publication format, subject scatter, authorship characteristics, age
of citations, geographic distribution, and language distribution; (2) productivity of journal titles; (3) the role of self-citation;
and (4) how selected bibliometric indicators apply. Some of the findings include: journal articles are most frequently cited;
English language publications dominate the literature; there is a trend of multiple authorship; and the pattern of aging is
below the norm for medical literature. The results of the study can provide a benchmark to measure the user behavior of a
particular group of researchers as well as for the provision of collection development and management decisions.
This revised version was published online in August 2006 with corrections to the Cover Date. 相似文献
3.
Norris Fran H.; Murphy Arthur D.; Baker Charlene K.; Perilla Julia L.; Rodriguez Francisco Gutiérrez; Rodriguez José de Jesús Gutiérrez 《Canadian Metallurgical Quarterly》2003,112(4):646
Prevalence rates of trauma and posttraumatic stress disorder (PTSD) were estimated from a probability sample of 2,509 adults from 4 cities in Mexico. PTSD was assessed according to Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, 1994) criteria using the Composite International Diagnostic Interview (CIDI; WHO, 1997). Lifetime prevalence of exposure and PTSD were 76% and 11.2%, respectively. Risk for PTSD was highest in Oaxaca (the poorest city), persons of lower socioeconomic status, and women. Conditional risk for PTSD was highest following sexual violence, but nonsexual violence and traumatic bereavement had greater overall impact because of their frequency. Of lifetime cases, 62% became chronic; only 42% received medical or professional care. The research demonstrates the importance of expanding the epidemiologic research base on trauma to include developing countries around the world. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
4.
The authors propose a behavioral decision theory relevant to the maintenance of desirable identities. The theory, termed deviance regulation theory (DRT), predicts that actions translate into meaningful identities to the extent that they cause the individual to deviate from reference group norms. This straightforward proposition is used to predict the patterning of behavior across a wide array of social contexts. The authors present evidence that predictions generalize across Eastern and Western cultures and to both personal and collective identities. Finally, they show how DRT alters current theoretical assumptions about social motives and social and cultural influence, and they illustrate how it can help explain the structure of both informal and formal social forces. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
5.
Charlene Xie 《Expert Systems》2010,27(5):388-398
Abstract: The paper describes a model‐driven decision support system for risk analysis in product development, based on an European Commission‐funded project. The model can be used to simulate the life cycle of a large batch of products and track products in operation and service phases with consideration of design and manufacturing phases. This provides some useful benefits – in particular, being able to generate composite results when the product life is subject to unpredictable events, which makes the system's behaviour non‐linear. A case study is conducted through a domestic appliance in the field trial from a manufacturing company, and the results indicate that the model can enable developers or manufacturers to understand the behaviour and characteristics of products or systems in the future use and to predict the cost of any changes in the pattern of their life. 相似文献
6.
Chin Chiat Lee Charlene Li Ching Ong Paul Wan Sia Heng Lai Wah Chan 《Drug development and industrial pharmacy》2013,39(2):206-214
The effectiveness of an interactive mixture as a rapid drug delivery system is compared with that of a solid dispersion. The influences of drug load, particle size, and crystallinity of these test systems are investigated. The interactive mixtures and solid dispersions were prepared from polyethylene glycol (PEG) 3350 and hydrophobic nifedipine drug by means of physical mixing and melting methods, respectively. The formed products were subjected to drug particle size and crystallinity analyses, and dissolution tests. In comparison with the interactive mixtures, the solid dispersions with low drug load were more effective as a rapid drug delivery system, as the size of a given batch of drug particles was markedly reduced by the molten PEG 3350. The rate and extent of drug dissolution were mainly promoted by decreasing effective drug particle size. However, these were lower in the solid dispersions than in the interactive mixtures when a high load of fine drug particles was used as the starting material. This was attributed to drug coarsening during the preparation of the solid dispersion. Unlike solid dispersions, the interactive mixtures could accommodate a high load of fine drug particles without compromising its capacity to enhance the rate and extent of drug dissolution. The interactive mixture is appropriate for use to deliver a fine hydrophobic drug in a formulation requiring a high drug load. 相似文献
7.
Binghui Deng Jason T. Harris Charlene M. Smith Jian Luo 《Journal of the American Ceramic Society》2022,105(2):990-1000
The mechanics of glass-ceramics subjected to sharp contact or other loading conditions remain elusive, even after being commercialized in many industrial applications. We present work herein to reveal atomic details of such deformations that are otherwise extremely difficult to probe experimentally for a lithium disilicate (LS2) and β-quartz containing glass-ceramics via molecular dynamics simulations. Specifically, the materials are comprised of LS2 and β-quartz nanocrystals in a residual glass matrix. Regardless of the deformation mechanism, whether it be nanoindentation or crack propagation for samples with pre-existing flaws, we observe that the LS2 nanocrystal itself undergoes substantial deformation, either by activating dislocations, forming an amorphization zone, or by initiating microcracks at glass-crystal interfaces or weak crystallographic planes. In contrast, the β-quartz nanocrystal is not easily deformed and remains almost intact with minimal plastic deformation, thereby forcing shear flow and crack propagation pathways to predominately occur in the residual glass and/or at interfaces. The dramatic difference between the crystalline phases also manifests itself in the deformation mode of interfaces under pure shear loading, in which shear bands preferably occur at the LS2-glass interfaces, while cavities form at the β-quartz-glass interfaces. These observations significantly advance our understanding of glass-ceramics and pave ways to exploit the understanding for more applications. 相似文献
8.
Molly K. Reif Jennifer M. Wozencraft Lauren M. Dunkin Charlene S. Sylvester Christopher L. Macon 《Journal of Great Lakes research》2013
The U.S. Army Corps of Engineers (USACE) Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) collected its first airborne coastal mapping data on the Great Lakes in 1995. Since then, the JALBTCX has collected nearly 5 billion elevation and depth measurements and created over 2000 geographic information system (GIS) products for the shorelines of the Great Lakes. With improvements in airborne coastal mapping technology and the introduction of regional management for the USACE, surveys expanded into the regional scale, multi-sensor National Coastal Mapping Program (NCMP). The NCMP was initiated in 2004 to produce recurrent, regional, high-resolution light detection and ranging (lidar) elevation data and hyperspectral and aerial imagery to support regional sediment management, regulatory functions, flood damage reduction, asset management, emergency operations, and environmental stewardship. The JALBTCX is a collaboration among the USACE, the U.S. Naval Oceanographic Office (NAVOCEANO), and the National Oceanic and Atmospheric Administration (NOAA). The partners have worked together on airborne coastal mapping and charting since the late 1980s with the goal of advancing airborne lidar bathymetry and associated technologies. The collaboration has fielded three generations of airborne sensors and has transferred this technology to the commercial sector, supporting an expanding market for bathymetric lidar. The purpose of this paper is to provide an overview of the history of USACE survey efforts in the Great Lakes (1995–2012), an in-depth review of the resulting imagery and lidar data products, and new information product developments and applications to support environmental and coastal engineering throughout the Great Lakes region. 相似文献
9.
Reasoned that the Castro government in Cuba represents an important negative reference group for Cuban Americans in the US. Exp I asked 43 Cuban-American undergraduates to give their opinions on issues surrounding the liberalization of relations between Cuba and the US. As expected, opinions were more opposed to such liberalization when an ostensible representative of the Castro government was quoted as favoring it than when no mention was made of the Castro government. Exps II and III (137 Ss) tested the prediction that utilization of negative reference groups would be mediated by dispositional self-consciousness. In Exp II, Ss gave their opinions after favorable opinions had been attributed to officials of the Castro government. Opposition among these Ss was positively correlated with their public self-consciousness but was unrelated to private self-consciousness. Exp III replicated the effect of public self-consciousness when the reference group was salient but yielded an ambiguous effect for an experimental manipulation of self-focus. Findings appear to confirm the role of dispositional self-consciousness in reference-group behavior. Moreover, they appear to suggest that Ss used their opposition to the negative reference group for self-presentational purposes rather than for self-definitional purposes. (21 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
10.