金具零部件表面防腐蚀试验研究

随着经济的持续高速增长，各行业用电需求增大。在加快特高压骨干电网建设的同时，提高现有电网的输电能力、输电质量成为重中之重。金具是海上换流站的重要组成部分，海洋环境的特殊性，对金具提出了更高的耐腐蚀性能要求。为了探究海洋环境对金具的腐蚀性，选用ZL101A和ZL102两种典型的铝合金金具，采用5种辅助防腐蚀工艺获得5种耐腐蚀样本，并模拟海上工况对其分别进行盐雾腐蚀试验，得出最优防腐蚀工艺。研究表明：ZL101A和ZL102两种铝合金具有一定的耐腐蚀性能，ZL101A铝合金的耐腐蚀性能强于ZL102铝合金的；抛丸处理的防腐措施在ZL101A铝合金样本中的防腐蚀表现要强于ZL102铝合金样本的；阳极氧化在两种材质中防腐蚀表现均为优异，是最优异的防腐蚀工艺。     

基于小波分析对地面电场信号的去噪及闪电信息提取

基于小波分析方法,通过对7种小波函数在误差控制和阈值方法选取上的对比,参考信噪比及均方误差等计算结果,选取了较为合理的Rigrsure阈值分析方法和sym5小波函数作为地面大气电场信号的去噪处理方法.该方法不仅能够较好地对电场信号波形平滑处理,降低电场波形中噪声信号的叠加度,还可保留闪电引起的电场的快速变化.在此基础上,利用差分计算方法实现了对闪电信号的自动识别,引入了总闪电频数误差及分时段闪电频数与人工分析结果的相关系数等2个参考量来选取差分计算方法中电场差分阈值,通过该方法可以实现闪电频数和极性等有关信息的提取.     

Variations in Variation and Selection: The Ubiquity of the Variation-and-Selective-Retention Ratchet in Emergent Organizational Complexity, Part II: Quantum Field Theory

If the general arguments concerning theinvolvement of variation and selection inexplanations of ``fit'' are valid, then variationand selection explanations should beappropriate, or at least potentiallyappropriate, outside the paradigm historisticdomains of biology and knowledge. In thisdiscussion, I wish to indicate some potentialroles for variation and selection infoundational physics – specifically inquantum field theory. I will not be attemptingany full coherent ontology for quantum fieldtheory – none currently exists, and none islikely for at least the short term future. Instead, I wish to engage in some partiallyspeculative interpretations of some interestingresults in this area with the aim ofdemonstrating that variation and selectionnotions might play a role even here. Ifvariation and selection can survive in even asinhospitable and non-paradigmatic a terrain asfoundational physics, then it can surviveanywhere.     

The influence of chronic nicotine treatment on stress-induced gastric ulceration and emptying rate in rats.

Ten-day treatment with nicotine (5, 25 or 50 micrograms/ml drinking water) dose-dependently intensified gastric ulceration induced by cold-restraint, and emptying rate. Stomach contractions produced by graded doses of bethanechol i.v. were elevated further by nicotine treatment. It is suggested that chronic nicotine administration produces hypersensitivity of the gastric muscarinic receptors; stomach hypermotility contributes to the ulcer-worsening action of the alkaloid.     

工艺规划系统中动态模式分类的研究

提出了工艺规划系统中动态模式分类（pattern classification）的概念，介绍了模式分类判定树和动态模式分类的基本原理，并对动态模式分类的聚类质量标准进行了研究。动态模式分类是基于实例归纳（case based reasoning,CBR)的自动分类过程，具有自学习和自完善的功能。     

双层钙钛矿Sr2FeMoO6，Ba2FeMoO6的电磁性质研究

分析了双层钙钛矿结构的锰氧化合物Sr2FeMoO6,Ba2FeMoO6物相结构和电磁学性质,对巨磁阻效应进行了探讨,揭示了Sr2FeMoO6样品为半导体导电性,Ba2FeMoO6样品为金属导电性.     

Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL

Resequencing genes provides the opportunity to assess the full spectrum of variants that influence complex traits. Here we report the first application of resequencing to a large population (n = 3,551) to examine the role of the adipokine ANGPTL4 in lipid metabolism. Nonsynonymous variants in ANGPTL4 were more prevalent in individuals with triglyceride levels in the lowest quartile than in individuals with levels in the highest quartile (P = 0.016). One variant (E40K), present in approximately 3% of European Americans, was associated with significantly lower plasma levels of triglyceride and higher levels of high-density lipoprotein cholesterol in European Americans from the Atherosclerosis Risk in Communities Study and in Danes from the Copenhagen City Heart Study. The ratio of nonsynonymous to synonymous variants was higher in European Americans than in African Americans (4:1 versus 1.3:1), suggesting population-specific relaxation of purifying selection. Thus, resequencing of ANGPTL4 in a multiethnic population allowed analysis of the phenotypic effects of both rare and common variants while taking advantage of genetic variation arising from ethnic differences in population history.     

Alcohol dehydrogenase 2 is a major hepatic enzyme for human retinol metabolism

The metabolism of all-trans- and 9-cis-retinol/ retinaldehyde has been investigated with focus on the activities of human, mouse and rat alcohol dehydrogenase 2 (ADH2), an intriguing enzyme with apparently different functions in human and rodents. Kinetic constants were determined with an HPLC method and a structural approach was implemented by in silico substrate dockings. For human ADH2, the determined K_m values ranged from 0.05 to 0.3 μM and k_cat values from 2.3 to 17.6 min⁻¹, while the catalytic efficiency for 9-cis-retinol showed the highest value for any substrate. In contrast, poor activities were detected for the rodent enzymes. A mouse ADH2 mutant (ADH2Pro47His) was studied that resembles the human ADH2 setup. This mutation increased the retinoid activity up to 100-fold. The K_m values of human ADH2 are the lowest among all known human retinol dehydrogenases, which clearly support a role in hepatic retinol oxidation at physiological concentrations. Received 12 October 2006; received after revision 6 December 2006; accepted 8 January 2007