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1.
2.
N M Nazarov N V Doronina Iu A Trotsenko E Iu Malykh N A Bitsadze 《Aviakosmicheskaia i ekologicheskaia meditsina》2004,38(5):42-46
Bacterial strains were screened to transform to end-products (carbon monoxide and water) elevated concentrations of acetone, acidic acid, and ethanol in a biocatalyst with an immobilized bacterial association cultivated on solid foam polyvinyl acetate (FPVA). The innocuous association amalgamated Paracoccus denitrificans VKM V-1324, Pseudomonas esterophilus VKM V-1736D and Achromobacter parvulus VKM V-1541D. The biocatalyst was tested with the help of classic methods and equipment for microbes cultivation. Microbial growth was assessed in the optical density units. Comparative evaluation of the biocatalytic activity was performed on gas-chromatographer Pue Unicam-104. Based on test results, specific rates of oxidation of acidic acid, ethanol and acetone per one g of FPVA were 0.75, 0.72, and 0.67 mg/hr, respectively. 相似文献
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5.
Circannual variation in lymphocyte subsets, revisited 总被引:2,自引:0,他引:2
BACKGROUND: Circadian and circannual variations in lymphocyte subsets, especially CD8+ T-lymphocytes, have been reported. This study focuses on CD4+ T-lymphocyte seasonal variation over a 6-year 8-month period. STUDY DESIGN AND METHODS: Lymphocyte subsets were quantitated monthly for four healthy individuals from 1986 through 1992 as part of a flow cytometry quality-control program. RESULTS: In general, there were no significant seasonal changes in the total number of white cells or in total lymphocyte counts. The absolute numbers of CD4+ T-lymphocytes were lowest in summer when the CD8+ T-lymphocytes were highest. Mean CD4+ T-lymphocyte counts were 846, 967, 618, and 695 per microL for Subjects 1 through 4, respectively, in winter and 432, 670, 355, and 766 per microL, respectively, in summer. Two healthy subjects had CD4+ T-lymphocyte counts lower than 300 per microL on one or more occasions during the study period. In three of the four subjects, the percentage of B-lymphocytes in winter was almost double that in summer. In one of the four subjects, no circannual rhythm was observed in these lymphocyte subpopulations. CONCLUSION: The seasonal variation in CD4+ T- lymphocyte counts demonstrated in three healthy individuals over almost 7 years is again of interest in light of renewed consideration of using surrogate tests, such as CD4+ T-lymphocyte counts, to screen for AIDS- like diseases that may be in the blood supply. 相似文献
6.
The family history in family practice: a questionnaire study 总被引:9,自引:7,他引:2
OBJECTIVES: Our aims were to investigate family medical history taking in
general practice, and to evaluate the value attached to the family medical
history as an aid to decision making in general practice. METHOD: A postal
questionnaire survey was conducted among all 291 GPs working within the
Calderdale and Kirklees Health Authority area. Each questionnaire was
followed by a reminder. The main outcome measures were answers to questions
on routine and opportunistic family history taking and a question about
transmitting knowledge about genetic risk to other members of the family.
Questions were also posed about the value attached to the family medical
history as an aid to decision making. RESULTS: A total of 193 GPs returned
the questionnaire (response rate 66.3%). On registration, 94.3% of GPs
indicated that enquiries were made about a family history of coronary heart
disease. Breast and colorectal cancer were specifically asked about by
48.4% and 30.7% of GPs, respectively. One-fifth of respondents indicated
that they asked a general question about family medical history. A little
over one-quarter of respondents indicated that they made opportunistic
enquiries about the family history or suggested that the patient should
inform other members of the family about possible risks. In the scenarios
highlighted in this study, the majority of respondents felt that the family
medical history had value as an aid to decision making. This was
particularly the case for checking a patient's cholesterol (92.1%) and for
initiating referrals in younger patients with possible cancer-related
symptoms (three-quarters of respondents). CONCLUSION: GPs value the family
medical history as an aid to decision making. Unfortunately, apart from
enquiries about coronary heart disease, routine or opportunistic family
history taking is not occurring in practice. Mechanisms need to be sought
to extract information from the family medical history so that it can be
more effectively used by GPs.
相似文献
7.
Semenov SY Svenson RH Bulyshev AE Souvorov AE Nazarov AG Sizov YE Posukh VG Pavlovsky A Tatsis GP 《Annals of biomedical engineering》2000,28(1):55-60
The proposed dielectrical relaxation model of the myocardium in the microwave spectrum has been verified both on test solutions and on normal canine myocardium. Furthermore, the model was utilized to reconstruct the changes in tissue properties (including myocardial bulk resistance and water content) following myocardial acute ischemia and chronic infarction. It was shown that the reconstructed myocardial resistance and water content correlate dynamically with the process of the development of acute myocardial ischemic injury. In chronic cases the reconstructed resistance and water content of infarcted myocardium are significantly different from that of normal myocardium: the resistance is lower and water content is higher than in normal myocardium. © 2000 Biomedical Engineering Society.
PAC00: 8764-t, 8719Xx 相似文献
8.
It is shown that C-reactive protein binds to streptolysin O, an exotoxin of hemolytic streptococcus, and neutralizes its hemolytic
activity. Incubation of C-reactive protein with the working dose of streptolysin O for 15–20 min at 37°C abolished the hemolysis
of subsequently added erythrocytes. The concentration of C-reactive protein that reduced hemolysis by 50% was on average equal
to 2.28±0.19 μg/ml. C-reactive protein antihemolytic activity was not affected by blocking of its phosphorylcholine-specific
sites with free phosphorylcholine, but decreased as a result of blocking with pneumococcal C-polysaccharide and, particularly,
with L-α-phosphatidylcholine. This indicates a hydrophobic nature of C-reactive protein-streptolysin O interaction. C-reactive
protein subunits retained antihemolytic activity, while the aggregated C-reactive protein lost part of it.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N
o
5 pp. 506–509, May, 1995
Presented by A. A. Totolyan, Member of the Russian Academy of Medical Sciences 相似文献
9.
T. A. Sapozhnikova F. S. Zarudii N. Zh. Baschenko S. F. Gabdrahmanova N. S. Makara R. Yu. Khisamutdinova N. A. Ivanova V. S. Nazarov 《Bulletin of experimental biology and medicine》2008,145(2):223-224
Therapeutic administration of 11-deoxymisoprostol had a hepatoprotective effect, which manifested in a decrease in the content
of alanine transaminase and aspartate transaminase in blood plasma, and produced a choleretic effect in rats with CCl4-induced toxic hepatitis.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 145, No. 2, pp. 183–184, February, 2008 相似文献
10.
Nazarov LU Akopian AS Agabelian AM Minasian AM Gevorkian GL 《Klinichna khirurhiia / Ministerstvo okhorony zdorov'ia Ukra?ny, Naukove tovarystvo khirurhiv Ukra?ny》1993,(2):32-34
In the clinic, at preoperative preparation of the patients with cancer of the colon complicated by perifocal inflammation, the irrigation of a tumour area, using antibacterial preparations, is employed. After laparoscopy, a drainage tube with microirrigator for perfusion of the antibacterial solution is introduced to the region of tumour location. Using the method described, 25 patients were prepared for the operation. Their state improved after 7-8 days. One-stage radical operation was performed in 20 patients. Of them in 17, primary intestinal anastomosis was created. 相似文献