An experimental study of intravascular stent in abdominal aorta of atherosclerotic miniature pigs.

To study the effects of nitinol alloy stent in the treatment of atherosclerotic arterial stenosis, eight miniature pigs were subject to abdominal aortic balloon denudation and high-fatty food. Then 8 nitinol alloy stents were implanted into each abdominal aortas of pigs. The pigs were equally divided into two groups. One group was given captopril (3 mg / kg / d). All animals were sacrified) for pathological examination 6 to 10 months after stent implantation. The degree of arterial intima proliferation in the areas of stent implantation not significantly different from that of areas of balloon denudation alone; the atherosclerotic lesions were found at the arterial surface of stent implantation sites. The intima layer was rich in smooth muscle cells, with atherosclerotic plaque formed around the stent wire. On the other hand, significant decrease in arterial intima proliferation was found in group Ⅱ with no atherosclerotic plaque. The arterial stenosis resulting from atherosclerotic lesion could not be     

Experimental study on the occlusion of arterial blood flow by the implantation of nitinol alloy stents.

To evaluate the occlusion of arteries, 6 conic intravaseular endoprosthetic stents of titanium-nickel alloy were implanted transluminally to the right external iliac arteries in 2 normal dogs and 4 normal pigs. The stent was characterized by ductility below 313 K (40℃) and restoration memory-shape between 313-319 K. The diameter of the large end of conic stent was 4.0 mm (dog) and 4.5 mm(pig). The topographic anatomy showed that the external iliac artery was near complete occlusion, with a very small residual lumen (about 1 mm in diameter) in dogs at 6 months, with complete occlusion in pigs at 8 months. The histopathological examination indicated that the arterial intima of the upper branch from the stented site was smooth, and that neither inflammatory cell infiltration nor foreign giant cell reaction was found. The newly formed granulation tissue inside the stent came from emboli organization. These results suggest that the shape-memory alloy stent has good biocompatibility and the conic intravascnla     

急性胰腺炎外分泌功能的变化和影响因素

急性胰腺炎(acute pancreatitis，AP)是一类以胰酶激活和自身消化为主要特征的无菌性化学性炎症，其中，胰腺外分泌功能的亢进在其发生和发展中有重要作用。但是，AP发生后胰腺外分泌功能又如何变化呢?对于这一问题还存在着许多争论。常规抑酶药物疗效的不确定性和一些实验依据支持AP后胰腺外分泌趋于抑制的观点；而大多数实验证实外分泌功能在AP后是亢进的。这两种观点相互推动，促进了这一领域的发展并取得了不少突破。现将近年来该领域的成果综述如下。     

腰椎后路椎旁肌间隙入路的解剖学与影像学观察

目的:观察腰椎周围肌间隙的解剖学与影像学特点,为腰椎后路椎旁肌间隙入路的选择和操作提供形态学依据.方法:选取18具成人尸体湿性躯干标本,一侧行局部解剖观察腰椎周围肌肉及其毗邻结构,另一侧行模拟肌间隙手术入路,观察不同肌间隙的解剖构成及其显露腰椎相关结构的特点;同时选取30例健康志愿者的腰部MRI与CT图像,观察肌间隙的影像学显示特点.结果:Wiltse间隙位于多裂肌与最长肌之间,由脂肪及疏松结缔组织填充,无血管、神经穿行;通过该间隙可清晰显露腰椎关节突关节、椎间孔及横突;75.0％的CT片和93.3％的MRI片可显示Wiltse间隙.LIMP间隙位于最长肌与髂肋肌之间,由一层薄而透明的筋膜分隔两肌,69.4％标本可见脊神经后支的肌支穿行间隙内;该间隙可满意显露椎间孔区及椎弓根;41.6％的CT片和56.6％的MRI片可显示LIMP间隙.Watkins间隙位于髂肋肌与腰方肌之间,由腰背筋膜中层及少量脂肪分隔肌肉形成,75.0％标本可见脊神经后支的皮支及伴行血管走行;该间隙可满意显露椎间孔及椎体两侧;63.3％的CT片和86.6％的MRI片可显示Watkins间隙.结论:熟悉腰椎不同肌间隙的形态特点及穿行结构,术前影像学准确观测有助于椎旁肌间隙入路的选择与操作.     

克隆氏病14例延误诊治临床分析

克隆氏病是消化道非特异性炎性疾病,误诊率高,若处理不当可带来严重后果。本文总结我院近10年错误诊治14例,就其原因分析如下。临床资料本组男9例,女5例。最小年龄8个月,最大年龄53岁,平均年龄26.5岁。本组误诊急性阑尾炎1例,急性弥漫性腹膜炎4例,消化性溃疡并大出血1例,肠套叠1例,肠梗阻2例,肠结核并结核性腹膜炎1例,回盲部肿瘤4例。本组并发肠外病变有关节炎6例,口腔粘膜溃疡5例,肋软骨炎2例,肛瘘2例,杵状指2例,结节性红斑1例,慢性淋巴性甲状腺炎1例,幽门梗阻1例,肝炎1例。本组死亡5例。其中死于肠瘘4例,乙状结肠克隆氏病并发中毒性巨结肠炎1例。余9例随访2～8年,无症状者7例,仅有轻度腹泻2例。     

《GBZ/T16029-2004》中一氧化氮和二氧化氮采样方法存在问题和对策初探

目的 对串联法与《GBZ/T16029 - 2004》中一氧化氮和二氧化氮的采样方法进行比较.方法分析GBZ/T16029 - 2004法与串联法测定结果.结果 GBZ/T16029 -2004法发生二氧化氮与总氮的量倒置.结论 利用串联法采集一氧化氮和二氧化氮更方便,数据更精确.     

诸城市2005～2009年外来妇女HIV感染状况分析及防治对策探讨

目的了解外来妇女HIV感染状况,探讨艾滋病防治对策。方法对2005-2009年外来妇女调查、检测资料进行分析。结果外来妇女感染率为1.46%,发现途径以专题调查、医疗机构外来妇女就诊发现为主。云南省占58%,文盲占47%,少数民族占48%。结论妇女在人类繁衍中的重要地位,以及艾滋病的性接触传播、母婴传播途径因素的影响,决定了做好外来妇女调查和HIV抗体检测工作的重要性。定期开展外来妇女专题调查是必要的。     

雌性自发性高血压大鼠去卵巢后对血压血管结构及血脂的影响

流行病学资料表明中年妇女心血管疾病的发病率比中年男性低，但绝经后发病率则逐年上升，接近甚至超过同年龄段男性。这种现象已逐渐引起医学界的重视。有的研究表明老年妇女雌激素水平低下是其罹患心血管疾病增加的主要原因，老年妇女应用雌激素替代治疗后冠心病发病率和残废率显著下降，心血管事件减少50％～70％。目前雌激素对心血管的作用机制尚未明确，雌激素水平的降低可能通过影响脂类、糖及蛋白质的代谢。     

肝圆韧带在修补胃十二指肠穿孔中的应用(附50例报告)

在胃、十二指肠急性穿孔修补手术中,单纯缝合和大网膜嵌入缝合被广泛应用并取得了肯定的疗效。但仍有部分病例用这两种方法不能满意地修补。1985～1989年,对用上述方法难以修补的穿孔,我们用肝圆韧带修补50例,现作初步总结。临床资料本组均为男性,年龄23～61岁。穿孔原发病变     

气相色谱-质谱测定鞋用胶粘剂中正己烷方法的研究

[目的]研究鞋用胶粘剂中正己烷的测定方法.[方法]胶粘剂样品经无水乙醇萃取后,吸取萃取液直接进样,经DB-5MS柱分离,质谱检测.[结果]在所给的实验条件下,正己烷与萃取剂乙醇及胶粘剂中其它的组分分离效果较好,进样0.4μl,浓度为0.00～19.80 mg/ml的正己烷(无水乙醇作溶剂),标准曲线方程为y=39303.8+481558×x,r=0.9991,变异系数RSD为1.9%～6.7%,回收率93.1%～95.5%.[结论]本方法适合鞋用胶粘剂中正己烷的测定.