应用超频叠加治疗化学灼伤所致皮肤色素沉着15例疗效分析

应用超频叠加治疗化学灼伤所致皮肤色素沉着１５例疗效分析上海市化工职业病防治研究所陈德荣王教梅王柯我们自１９９５年以来，应用ＣＥＭ－６Ａ高级电脑美容美体机中的超频叠加项目和祛色精华素治疗化学灼伤所致皮肤色素沉着１５例，取得良好效果。超声叠加治疗即指超声...     

彩色多普勒超声在Ⅱ型糖尿病患者下肢动脉中的诊断应用

目的：探讨彩色多普勒超声检测Ⅱ型糖尿病患者下肢动脉病变的诊断应用。方法：选择100例Ⅱ型糖尿病患者,对其下肢共1000个节段进行彩色多普勒超声检查。结果：Ⅱ型糖尿病患者下肢动脉病变为血管内膜粗糙增厚,动脉腔内粥样斑块及血管部分或完全闭塞,彩色多普勒示血管内彩色充盈缺损。结论：彩色多普勒超声对II型糖尿病患者下肢动脉病变的诊断及追踪观察有良好的应用价值。     

多普勒超声对支气管哮喘患者右心舒张功能的评价

支气管哮喘是呼吸系统的常见病、多发病,随着病情进展,严重时可导致肺循环压力增高,右心后负荷增加,最终右心及全心功能障碍。本文采用多普勒超声对55例支气管哮喘患者右心舒张功能进行观察分析,报告如下。     

流行性腮腺炎并睾丸炎对生育影响的随诊观察

本文分析了23例流行性腮腺炎并发睾丸炎者的临床表现,并结合随访观察,重点了解患者病愈后生育情况.现将结果报道如下.临床资料一、一般资料:23例并发睾丸炎的流行性腮腺炎者为我院1982～1988年住院患者,发病时均未婚,年龄12～24岁,均有发热、腮腺肿大及睾丸肿痛,腮腺炎病毒特异性IgM型抗体阳性.     

乌梅人丹质量标准的研究

目的:建立乌梅人丹的质量标准;方法:对制剂中乌梅用薄层色谱法进行定性鉴别,同时采用气相色谱法测定制剂中薄荷脑含量以及采用高效液相色谱法测定制剂中甘草酸铵的含量.结果:平均回收率分别为103.5%、100.3%,RSD分别为0.76%(n=6)和1.03%(n=6).薄层图谱斑点清晰,空白无干扰.结论:方法简便、准确、重现性好,可有效控制该制剂的质量.     

高效液相色谱法测定健骨颗粒中仙茅苷的含量

目的：采用高效液相色谱法测定健骨颗粒中仙茅苷含量。方法：样品经水溶解后上中性氧化铝柱净化，采用色谱柱Capeell PAK ODS—C18（4．6mm×250mm，5μm），以乙腈-0．1％磷酸溶液（25：75）为流动相，流速0．8mL·min^-1，检测波长为283nm。结果：线性范围为3．135—62．7μg·mL^-1，r=0．9999；平均加样回收率（n=9）为97．3％。结论：该方法灵敏度高，专属性好，操作简便，重复性好。     

失喑治验

失喑是临床常见病症，中医有暴喑久喑之分，采用辨证论治，疗效显著。     

全氟辛烷磺酸对大鼠仔鼠学习记忆能力的影响

Objective To study the effects of prenatal and postnatal perfluorooetane sulfonate (PFOS) exposure on spatial learning and memory, N-methyl-D-aspartate receptor 2B (NR2B) mRNA and protein level in frontal cortex and hippoeampus of rat pups and to explore the mechanism of developmental neurotoxicity induced by PFOS. Methods Twenty-eight pregnant mrs were randomly divided into three groups in proportion of 3: 2: 2,including control group (C), low dose group (L) and high dose group (H) by means of randomized number table, which respectively received 0,7.2, 14.4 mg/kg PFOS feed from pregnancy day 0 to postnatal day(PND)30 by free feedings. The animal models of prenatal and postnatal non-exposure (CC), prenatal exposure (LC and HC), postnatal exposure (CL and CH), and prenatal and postnatal exposure (LL and HH) to PFOS were established by cross-fostering method. The spatial learning and memory were measured by water maze experiment,the NR2B mRNA levels in frontal cortex of rat pups was determined with semi-quantitative RT-PCR, NR2B protein express in cerebral cortex (frontal and tempera]cortex) and hippocampus (CAI, CA3, CA4 and DG regions) of rat pups was detected by immunohistochemistry. Results The escape latency of CL, CH, LL and HH groups pups in water maze experiment were (99. 83±25.77) s, (111.30±17. 82) s, (106. 40±18. 71) s, (107.70±16. 85) s, and longer as compared with CC group[(54.90±26.69)s](q value were 4.349,4.773,6.026 and 5.641, respectively,P<0. 01). The number of errors of HH group rat pups entering dead end was (22. 30±7.56) at the training day 4,and it was significantly higher than that of CC group (9. 80±4. 64) (q=5. 173,P<0. 01). The NR2B mRNA levels of frontal cortex of pups in HC group at PND1 ,and LC group, HC group and HH group at PND14 were (0. 167±0. 008), (0. 364±0. 035), (0. 341±0. 030) and (0. 328±0. 045) respectively,which were significantly lower than CC group (0.271±0.060) and (0.465±0.067) (q values were 3. 547, 3. 739, 4. 597 and 5. 006, respectively, P<0.05) . The results of immunohistochemistry indicated that NR2B protein express of the hippocampus CA1 region of pups in LC group was (0.091±0.005),and showed significant lower than CC group which was (0. 123±0.009) at PND1 (q=5. 209 ,P<0. 05). At PND14, the effect of PFOS extended to cerebral cortex and hippocampus regions. At PND28, the effects of PFOS were showed in hippocampus CA1, CA3 and temporal cortex regions. Conclusion Prenatal and postnatal exposure to PFOS should result in the spatial learning and memory damage,and the mechanism might be possibly involved in the decrease of NR2B level in cerebra lcortex and hippocampal formation regions.