Hidden Markov modeling using a dominant state sequence with application to speech recognition

Approximate maximum likelihood (ML) hidden Markov modeling using the most likely state sequence (MLSS) is examined and compared with the exact ML approach that considers all possible state sequences. It is shown that for any hidden Markov model (HMM), the difference between the approximate and the exact normalized likelihood functions cannot exceed the logarithm of the number of states divided by the dimension of the output vectors (frame length), which is negligible for typically used values of vector dimension (128–256) and number of states (2–30). Furthermore, for Gaussian HMMs and a given observation sequence, the MLSS is typically the sequence of nearest neighbor states in the Itakura-Saito sense, and the posterior probability of any state sequence which departs from the MLSS in a single time instant decays exponentially with the frame length. Hence, for a sufficiently large frame length the exact and approximate ML approaches provide similar model estimates and likelihood values. The results and their implications on speech recognition are demonstrated in a set of experiments.     

Oxygen dependency of retinal adhesion

PURPOSE: Normal retina is firmly attached to the retinal pigment epithelium, but the force of this adhesion drops precipitously within the first 2-3 min after enucleation. The purpose was to study metabolic factors that might be relevant to this postmortem failure of adhesion. METHODS: Dutch rabbit retina was manually peeled from the retinal pigment epithelium on strips of enucleated eyecup within a 37 degrees C bath. Retinal adhesiveness was measured by observing the amount of retinal pigment epithelium that remained adherent to the retina. RESULTS: Autologous whole blood in place of salt solution retarded the decrease in adhesiveness. A solution of hemoglobin alone was similarly effective, whereas methemoglobin solution failed to help the persistence of retinal adhesion. Bubbling oxygen into the salt solution and circulating it to avoid oxygen depletion at the tissue boundary also proved effective at sustaining retinal adhesiveness. Eyes made ischemic in vivo for 5 min or longer, by elevating intraocular pressure, showed virtually no retinal adhesion when enucleated immediately thereafter. However, eyes made ischemic for 10 min, but allowed to regain circulation for 5 min before enucleation, showed a return of retinal adhesiveness to 80% of normal. CONCLUSIONS: Oxidative metabolism is critical to the maintenance of retinal adhesiveness, and the effects of oxygen deprivation on adhesion are reversible within a certain time period.     

Time interleaved optical sampling for ultra-high speed A/Dconversion

A scheme is proposed for increasing the sampling rate of analogue-to-digital conversion by more than an order of magnitude by combining state-of-the-art A/D converters with photonic technology. Ultra-high speed sampling is performed optically by a multiwavelength pulse train. Wavelength demultiplexers convert the high repetition rate data stream of samples into parallel data streams that can be handled by available electronic A/D converters     

Self-stabilized nonlinear lateral modes of broad area lasers

The lateral modes of broad area lasers are investigated theoretically. The nonlinear interaction between optical field and effective refractive index leads to a saturable nonlinearity in the governing field equation, so that self-modulated solutions are found to be stable with increased current injection above saturation intensity. We derive approximate analytical solutions for traveling wave fields within the broad area laser. The field amplitude consists of a small ripple superimposed on a large dc value. Matching fields at the boundary determines the modulation depth and imparts an overall phase curvature to the traveling wave mode. There are multiple lateral modes for a given set of operating conditions, and modes with successively more lobes in the ripple have greater overall phase curvature. In contrast to the linear problem, several lateral modes can achieve the same modal gain, for a given injected current density, by saturating the gain to different extent. Thus, these modes would exhibit slightly different optical powers.     

Sorption of Aniline by Montmorillonite

Sorption of aniline by montmorillonite was studied by infra-red, X-ray diffraction and differential thermal analysis methods. The amount of aniline sorbed and the type of bonding depend upon the interlayer cations: anilinium, H⁺- and Al³⁺- give anilinium aniline ions, NH₄⁴-ammonium aniline ions, alkalis and alkaline earths except Cs are bonded to aniline through water bridges and transition metal cations are coordinated to aniline partly directly and partly through water bridges. Sorption does not occur in the complete absence of water.     

The Effects of Thermal Treatment on Associations between Fatty Acids and Montmorillonite

The sorption from CCl₄ solutions of acetic, lauric and stearic acids by montmorillonites saturated with H, Li, Na, K, Cs, Ca, Mg, Cu, Al and Fe, was studied by IR and X-ray methods combined with various thermal treatments. Two distinct species were detected in the clay phase, the carboxylic acid (RCOOH) and the carboxylate anion (RCOO⁻). The ratios of the two sorbed species were found to be dependent both on the nature of the exchangeable cation and on the chain length of the acid. In Al⁻, Fe⁻ and Cu—montmorillonites, the ionic species predominates whereas in Cs—montmorillonite the acidic species predominates. Stearic acid shows the highest tendency to dissociate. The following associations were identified as occurring in the interlayer space: (I) and (II) — linkages between COOH group and oxygen sheet of silicate layer or with hydrophobic structured water; (III) — linkage between a COOH group and an exchangeable cation through a “water bridge”; (IV) — direct linkage between a COOH group and an exchangeable cation; (V) — linkage between a COO⁻ group and an exchangeable cation through a “water bridge” and (VI) — direct linkage between a COO⁻ group and an exchangeable cation. Although several types of associations are associated with every homoionic montmorillonite, some are more predominant. Thus, with Cs, association (I) predominates. With Li, Ca and Mg, association (III) predominates and is transformed to (IV) after thermal dehydration; whereas with Na and K association (IV) appears in freshly prepared sample. Al, Fe and Cu—montmorillonites mainly produce association (V). This structure is transformed into (VI) in the case of Al—montmorillonite by stearic and lauric acids, only. In the case of Cu—montmorillonite, all the three acids are transformed into (VI), but at 200°C decarboxylation of lauric and stearic acids occur.     

The role of charcoal on DTA curves of organo-clay complexes: an overview

DTA of organo-clay complexes supplemented by other thermal analysis methods supplies information on the thermal reactions, properties and stability of the complex, the amount and properties of the adsorbed water in the organo-clay and on the bonding between the organic species and the clay. It is used to identify the mineral to differentiate between various complexes composed of the same clay and the same organic ligand and to establish their composition. During the gradual heating in oxidizing atmospheres the adsorbed organic material is oxidized, giving rise to significant exothermic peaks. DTA curves of organo-clays are divided into three regions: (1) the dehydration of the clay, (2) the thermal oxidation of the organic material and (3) the dehydroxylation of the clay. The exothermic oxidation reaction occurring during the gradual heating of the sample takes place in two steps, in the range 200–500 °C, oxidation of organic hydrogen and formation of water and charcoal, and 400–750 °C, oxidation of charcoal and formation of CO₂. The exothermic peak temperatures depend on the mineral and on the organic compound and on the types of bonding between these two components of the organo-clay complex. The present communication concentrates in the role of the combustion of charcoal in the study of the fine structure of the complex and of the type of associations between the organic compound and the clay.     

Medical marijuana

To evaluate the use of high-resolution magnetic resonance imaging (MRI) for the differentiation of skin tumors in the maxillofacial region, 60 patients (25 female) were examined in a 1.5-T whole-body MR imager with a 2.5-cm surface coil. Plain transverse T1-(TR 500 ms, TE 25 ms), T2-(2200 ms, TE 80 ms), fat-(TR 500 ms, TE 28 ms), and water-suppressed (TR 500 ms, TE 38 ms) SE sequences were used. Following the application of the paramagnetic contrast agent Gd-DTPA, transverse T-weighted and fat suppression sequences were repeated. Before and after contrast administration, tumor signal intensities and percent contrast enhancement were determined by a ROI technique. All tumors were classified by standard histologic technique and evaluated with regard to their response to contrast medium. Quantitative evaluation was performed by three independent radiologists. Additionally, signal- and contrast-to-noise ratios were calculated for each tumor type. All MRI findings were compared with histology. Significant contrast enhancement occurred in most tumors; malignant tumors displayed inhomogeneous enhancement. The optimal pulse sequences for tumor delineation are plain T1-weighted, water-suppressed, and contrast-enhanced fat-suppressed sequences. Tumors could not be specified by signal intensities or percent contrast enhancement, and CNR did not allow for malignant lesions to be differentiated from benign tumors. High-resolution MRI proved to be an adequate method for imaging skin tumors and their inner structure. Tumor typing was not possible by either contrast-administration or modification of sequence parameters. In this regard, further innovations in contrast agent design seem to be necessary.     

Coupled-mode theory for guided-wave optics

The problem of propagation and interaction of optical radiation in dielectric waveguides is cast in the coupled-mode formalism. This approach is useful for treating problems involving energy exchange between modes. A derivation of the general theory is followed by application to the specific cases of electrooptic modulation, photoelastic and magnetooptic modulation, and optical filtering. Also treated are nonlinear optical applications such as second-harmonic generation in thin films and phase matching.