Chiral metal-organic frameworks with tunable catalytic selectivity in asymmetric transfer hydrogenation reactions

Metal-organic frameworks(MOFs)have achieved great success in the field of heterogeneous catalysis,however,ifs still challenging to design MOF catalysts with enhanced selectivity.Here,we demonstrated a combination strategy of metal design and ligand design on the enantioselectivity—that is the enantioselectivities of chiral MOF(CMOF)catalysts could be significantly enhanced by the rational choice of metal ions with higher electronegativities and introducing sterically demanding groups into the ligands.Four isostructural Ca-,Sr-and Zn-based CMOFs were prepared from enantiopure phosphono-carboxylate ligands of 1,V-biphenol that are functionalized with 2,4,6-trimethyl-and 2,4,6-trifluoro-phenyl groups at the Supposition.The uniformly distributed metal phosphonates along the channels could act as Lewis acids and catalyze the asymmetric transfer hydrogenation of heteroaromatic imines(benzoxazines and quinolines).Particularly,the Ca-based MOF 1 with 2,4,6-trimethyl groups at the substituents exhibited enhanced catalytic performance,affording the highest enantioselectivity(up to 97%).It is also the first report of the heterogeneous catalyst with chiral non-noble metal phosphonate active sites for asymmetric transfer hydrogenation reactions with Hantzsch ester as the hydrogen source.The catalyst design strategy demonstrated here is expected to develop new types of chiral materials for asymmetric catalysis and other chiral applications.     

Promoting Bone Mesenchymal Stem Cells and Inhibiting Bacterial Adhesion of Acid-Etched Nanostructured Titanium by Ultraviolet Functionalization

Titanium(Ti) and its alloys are used extensively in orthopedic implants because of their excellent biocompatibility,mechanical properties and corrosion resistance. However,titanium-based implant materials face many severe complications,such as implant loosening due to poor osseointegration and bacterial infections,which may lead to implant failure. Hence,preparing a biomaterial surface,which enhances the interactions with host cells and inhibits bacterial adhesion,may be an optimal strategy to reduce the incidence of implant failure. This study aims to improve osseointegration and confer antibacterial properties on Ti through a combination of two surface modifications including nanostructuring generated by acid etching and ultraviolet(UV) light treatment.Our results showed that without UV treatment,the acid etching treatment of Ti surface was effective at both improving the adhesion of bone mesenchymal stem cells(BMSCs) and increasing bacterial adhesion. A further UV treatment of the acid-etched surface however,not only significantly improved the cell adhesion but also inhibited bacterial adhesion. The acid-etched nanostructured titanium with UV treatment also showed a significant enhancement on cell proliferation,alkaline phosphatase(ALP) activity and mineralization. These results suggest that such nanostructured materials with UV treatment can be expected to have a good potential in orthopedic applications.     

靖远电厂4号机高压外缸左右法兰温差过大现象分析

本文综述了靖远电厂４号机高压外红缸左右法兰温差过大现象，分析了产生温差的可能原因，希望有关单位确定温差控制范围。     

Influence of Billet Size on Flow, Solidification and Solute Transport in Continuous Casting

ListofSymbol　　B———Buoyancy ,m·s- 2 ;　　c———Concentrationofsoluteelement ;　　Cμ———Turbulentconstant;　　D———Diffusivityofsoluteelement ,m2 ·s- 1 ;　　fl,fs———Liquidandsolidfraction ;　　fμ———Turbulentcoefficient ;　　h———Enthalpy ,J·kg- 1 ;　　k———Turbulentkineticenergy ,m2 ·s- 2 ;　　kp———Equilibriumpartitioncoefficient;　　Kp———Permeabilityofmushyzone ,m2 ;　　K0 ———Permeabilitycoefficient;　　p———Pressure ,Pa ;　　Pr———Prandtlnumber ;…     

数字图像的一种并行处理

利用Ｆｏｕｒｉｅｒ－阶光滑离散化的分析，提出对其并行化分析，对图像增强进行研究，在同等存贮环境中，并行算法优于串行处理，为图形并行处理提出了一种方法。     

Measurement System of Uniformity between Breech Horizontal Platform and Datum Tube Axis of Rocket Artillery

The purpose of this development is to detect the parallelism between the breech horizontal platform and the datum tube axis of the rocket artillery. The located aiming mechanism at the muzzle and located adjustment mechanism at the breech are designed in the system. Besides those, the system also uses an autocollimator with accuracy of 1″ and a collimating mirror together to determine the axis of the datum tube. An electronic level with accuracy of 2″ is employed to measure and display the value of the included angle and the parameter of the inclined direction. The entire accuracy of this system is σ≤± 9.1″. This paper describes the composition and the operating principle of the system and analyzes the accuracy. The development of this system supplies reliable measurement method for new rocket artilleries and artilleries, and this technology is of a good application prospect.     

Non-Steady Equilibrium during Pro-Eutectoid Ferrite Formation in Fe-0.2C Alloy

Ｔｈｅｐｒｅｃｉｐｉｔａｔｉｏｎｏｆｐｒｏ ｅｕｔｅｃｔｏｉｄｆｅｒｒｉｔｅｆｒｏｍａｕｓｔｅｎｉｔｅｉｓｃｏｎｔｒｏｌｌｅｄｂｙｄｉｆｆｕｓｉｏｎｉｎＦｅ Ｃａｌｌｏｙｓ .Ｗｉｔｈｔｈｅａｓｓｕｍｐｔｉｏｎｔｈａｔｔｈｅｍｉｇｒａｔｉｎｇｉｎｔｅｒｆａｃｅｉｓａｌｗａｙｓｉｎｌｏｃａｌｅｑｕｉｌｉｂｒｉｕｍ ,ｅａｒｌｙｉｎ 194 9,ＺｅｎｅｒＣ[1] ｅｘｐｌａｉｎｅｄｔｈｅｄｉｆｆｕｓｉｏｎａｌｇｒｏｗｔｈｏｆｐｒｏ ｅｕｔｅｃ ｔｏｉｄｆｅｒｒｉｔｅｂｙｕｓｉｎｇｔｈｅＦｉｃｋ’ｓｌａｗ .Ｓｉｎｃｅ…     

~(131)I-Lym-2单克隆抗体实验研究

不同浓度的~(131)I-Lym-2 MoAb与ARH-77和CEM细胞进行结合试验,结果表明:随浓度增大,结合值均升高;实验组裸鼠模型9只获得动力学数据。实验组和对照组注射~(131)I-Lym-2 MoAb后144h解剖,进行生物学分布(％D/g)测定,实验组肿瘤为16.88±12.64,肌肉为0.72±0.56。结果表明,~(131)I-131-Lym-2MoAb对临床B细胞淋巴瘤的放射免疫分析、显像有良好的效果。     

采用原水碳源的SBR法脱氮

前言 围绕SBR法脱氮的研究,一般认为采用好氧与缺氧相间的运行模式能够提高脱氮效果,在反硝化阶段习惯以甲醇作为碳源,由于甲醇属化学试剂,长期使用费用较大,本研究试以原水作为反硝化碳源进行SBR法脱氮,考察加入原水碳源后的总处理效果及其影响因素。     

Applications of Soliton Transmission Control in Optimal Design of Long－Haul Soliton Communication System

ＡｐｐｌｉｃａｔｉｏｎｓｏｆｃｈａｏｓｉｎｓｐｒｅａｄｓｐｅｃｔｒｕｍｃｏｍｍｕｎｉｃａｔｉｏｎｓＡｐｐｌｉｃａｔｉｏｎｓｏｆＳｏｌｉｔｏｎＴｒａｎｓｍｉｓｓｉｏｎＣｏｎｔｒｏｌｉｎＯｐｔｉｍａｌＤｅｓｉｇｎｏｆＬｏｎｇ－ＨａｕｌＳｏｌｉｔｏｎＣｏｍ...