HPLC-MS Method for Simultaneous Quantitative Determination of an Innovative Russian Gestagen and its Metabolites in Rat and Rabbit Blood Sera

Pharmaceutical Chemistry Journal - An HPLC-MS method for simultaneous quantitative determination of a novel gestagenic pharmaceutical and two of its metabolites in rat and rabbit blood sera was...     

Photodynamic inhibition of infection caused by drug-resistant variants of herpes simplex virus type I

Membranotropic amphiphilic chromophore merocyanine 540 sensitized photodynamic inhibition of drug-resistant and sensitive variants of type I herpes simplex virus in cultured Vero cell. Optimal conditions of photodamage to virus particles and infected cells were determined (merocyanine 540 concentration 1 M, illumination dose 32.5-65.0 kJ/m², exposure at early stages of infection). Infected cells actively bind the photosensitizer, which explains their selective photodamage.     

Three-phase response of mock-cell culture to long-term antiviral chemotherapy

Department of Inhibitors of Viral Activity, Belorussian Research Institute of Epidemiology and Microbiology, Ministry of Health of the Belorussian SSR, Minsk. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 107, No. 5, pp. 595–598, May, 1989.