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Multifunctional 3D Patternable Drug‐Embedded Nanocarrier‐Based Interfaces to Enhance Signal Recording and Reduce Neuron Degeneration in Neural Implantation 下载免费PDF全文
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Jui-Ting Weng Jiunn Ru Lai Wanjiun Liao 《Wireless Communications, IEEE Transactions on》2006,5(7):1676-1684
In this paper, we analyze node mobility for reliable packet delivery in mobile IP networks. In mobile IP, packets destined to roaming nodes are intercepted by their home agents and delivered via tunneling to their care of addresses (CoA). A mobile node may roam across multiple subnets. At each boundary crossing, a handoff is initiated such that the CoA is updated and a new tunnel is established. We consider both basic mobile IP handoff and smooth handoff. We find that reliable packet delivery in mobile IP networks can be modeled as a renewal process, because the retransmission over a new tunnel after each boundary crossing is independent of the previous history. We then derive the probability distribution of boundary crossings for each successful packet, based on which the packet reliable delivery time can be obtained. Our analytical model is derived based on a general distribution of residence time in a subnet and a general distribution of successful retransmission attempts in each subnet. The results can be readily applied to any distributions for both items. We also provide numerical examples to calculate the probability distribution of boundary crossings, and conduct simulations to validate our analytical results 相似文献
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Ray-Guang Cheng Cun-Yi Wang Li-Hung Liao Jen-Shun Yang 《Communications Letters, IEEE》2006,10(2):123-125
This work presents a wireless token-passing protocol, named Ripple, for wireless mesh networks (WMNs). In contrast to existing random-access approaches, Ripple uses a decentralized controlled-access approach to protect nodes from unintentional packet collisions and maximize the spatial reuse. The performance of Ripple under an error-free wireless channel was investigated and the accuracy of the analysis was verified by simulation. Simulation results also indicated that Ripple achieved throughput, stability, and QoS enhancement than that of 802.11 DCF under a highly loaded situation. 相似文献
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PE Sipila VJ Wiebe GB Hubbard SK Koester VD Emshoff JU Maenpaa GT Wurz RC Seymour MW DeGregorio 《Canadian Metallurgical Quarterly》1993,(15):2138-2144
The effects of long-term tamoxifen exposure on cell growth and cell cycle kinetics were compared between oestrogen receptor (ER)-positive (MCF-7) and ER-negative (MDA-MB-231) cell lines. In the MCF-7 cell line, prolonged tamoxifen exposure (0.5 mumol/l for > 100 days) blocked cells in G0-G1 of the cell cycle, and slowed the doubling time of cells from 30 to 59 h. These effects corresponded to an increase in the cellular accumulation of tamoxifen over time [mean area under concentration curve (AUC) = 77.92 mumoles/10(6)/cells/day]. In contrast, in the MDA-MB-231 cell line, long-term tamoxifen exposure had no obvious effect on the doubling time, and reduced cellular tamoxifen accumulation (mean AUC = 50.50 mumoles/10(6)/cells/day) compared to the MCF-7 cells. Flow cytometric analysis of MDA-MB-231 cells demonstrated that a new tetraploid clone emerged following 56 days of tamoxifen exposure. Inoculation of the MDA-MB-231 tetraploid clone and MDA-MB-231 wildtype cells into the opposite flanks of athymic nude mice resulted in the rapid growth of tetraploid tumours. The tetraploid tumours maintained their ploidy following tamoxifen treatment for nine consecutive serial transplantations. Histological examination of the fifth transplant generation xenografts revealed that the tetraploid tumour had a 25-30 times greater mass, area of haemorrhage and necrosis, a slightly higher mitotic index and was more anaplastic than the control neoplasm. The control wildtype MDA-MB-231 tumours maintained a stable ploidy following tamoxifen treatment until the eighth and ninth transplantation, when a tetraploid population appeared, suggesting that tamoxifen treatment may select for this clone in vivo. These studies suggest that prolonged tamoxifen exposure may select for new, stable, fast growing cell clones in vitro as well as in vivo. 相似文献
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1960-1970年那段时间被称为立体声的黄金岁月 ,那时要调试并建立一套立体声系统是非常简单的,整个系统只包括一对音箱,一个功放(纯A/V功放或附带收音功能)或纯粹的无线电接收器以及诸如唱片机这类型的音源即可,而设置过程更是简单,只需要连接很少的几根线,再将扬声器放到一个合适的位置就可以了。[编者按] 相似文献
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C. Y. Liao S. N. Atluri 《International journal for numerical methods in engineering》1991,32(6):1339-1361
An efficient method, based on the Schwarz–Neumann alternating technique, is presented for computing weight functions of a general solid (3-D as well as 2-D), with embedded or surface-flaw configurations. The total rate of change of the crack-opening displacements, due to simple perturbations of crack-dimension characteristics, is conveniently decomposed into the infinite-domain and boundary-correction parts. The former is determined from available analytical solutions of ideal-shaped cracks, whereas the latter is computed numerically by imposing nil boundary-traction requirements for the displacement field corresponding to the weight functions. Numerical examples, with solutions for 3-D weighted-average and local stress intensity factors, indicate that the proposed method is very accurate and efficient. 相似文献
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