Robust stabilization for uncertain time-delay systems containingsaturating actuators

A class of uncertain time-delay systems containing a saturating actuator is considered. These systems are characterized by delayed state equations (including a saturating actuator) with norm-bounded parameter uncertainty (possibly time varying) in the state and input matrices. The delay is assumed to be constant bounded but unknown. Using a Razumikhin approach for the stability of functional differential equations, upper bounds on the time delay are given such that the considered uncertain system is robustly stabilizable, in the case of constrained input, via memoryless state feedback control laws. These bounds are given in terms of solutions of appropriate finite dimensional Riccati equations     

A comprehensive introduction to the geometric theory of linearmultivariable systems

A simple tutorial introduction to the geometric theory of linear multivariable control is presented. This corresponds to approximately three two-hour lectures in a graduate-level course. The authors emphasise the intuitive control interpretation of the main geometric concepts. To this end, the authors focus interest on trajectory formulation for subspace invariance and discrete-time interpretation of the basic subspaces and their construction algorithms. Application of geometric theory for solving the disturbance decoupling problem is illustrated via two pedagogical examples     

The effect of chemical composition on the miscibility of styrene/acrylonitrile/fumaronitrile terpolymers with styrene/acrylonitrile copolymers

Blends were prepared of styrene–acrylonitrile–fumaronitrile (SANFN) terpolymers with styrene–acrylonitrile (SAN) copolymers and of SANFN terpolymers with SANFN terpolymers of different compositions. Miscibility was determined by differential scanning calorimetry. For three SANFN terpolymer compositions containing 11–17% fumaronitrile, a range of miscible SAN copolymers was defined. The miscibility can be predicted by using a Flory–Huggins-type mean-field approach.     

Gender differences in evaluations of tobacco and alcohol advertisements.

Examined the relation between gender and reactions to different styles of advertising tobacco and alcohol products among 41 females and 34 males (aged 12–16 yrs) and their parents (39 mothers and 36 fathers). Self-monitoring was also examined as a possible correlate. Ss rated magazine advertisements oriented toward the product's image or qualities. Girls liked image-oriented advertisements more and perceived them to be more persuasive than quality-oriented advertising. This gender difference was not observed among adults. All Ss liked image-oriented more than quality-oriented advertising. Moreover, image-oriented advertisements were seen as more persuasive than quality-oriented advertisements by girls' parents who were high in self-monitoring. Results suggest that girls in early adolescence may be particularly attentive to image-oriented commercials that portray smoking and drinking as desirable behaviors. (French abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Demonstration of an ion-implanted, wavelength-shifted quantum-well laser

A technique for fabricating many different wavelength lasers on the same wafer has been developed. High energy ion implantation was used to selectively blue shift the emission wavelength of an InP-based quantum well laser structure. This structure was then processed into fully functional broad-area lasers whose current threshold was unaffected by the implantation process, indicating extremely high material quality after bandgap-shifting. This process has the potential for the integration of not only different wavelength lasers, but also other devices, such as waveguides, detectors, modulators, etc., on a single wafer.     

Molecular Genetics of Conjunctival Melanoma and Prognostic Value of TERT Promoter Mutation Analysis

The aim of this study was exploration of the genetic background of conjunctival melanoma (CM) and correlation with recurrent and metastatic disease. Twenty-eight CM from the Rotterdam Ocular Melanoma Study group were collected and DNA was isolated from the formalin-fixed paraffin embedded tissue. Targeted next-generation sequencing was performed using a panel covering GNAQ, GNA11, EIF1AX, BAP1, BRAF, NRAS, c-KIT, PTEN, SF3B1, and TERT genes. Recurrences and metastasis were present in eight (29%) and nine (32%) CM cases, respectively. TERT promoter mutations were most common (54%), but BRAF (46%), NRAS (21%), BAP1 (18%), PTEN (14%), c-KIT (7%), and SF3B1 (4%) mutations were also observed. No mutations in GNAQ, GNA11, and EIF1AX were found. None of the mutations was significantly associated with recurrent disease. Presence of a TERT promoter mutation was associated with metastatic disease (p-value = 0.008). Based on our molecular findings, CM comprises a separate entity within melanoma, although there are overlapping molecular features with uveal melanoma, such as the presence of BAP1 and SF3B1 mutations. This warrants careful interpretation of molecular data, in the light of clinical findings. About three quarter of CM contain drug-targetable mutations, and TERT promoter mutations are correlated to metastatic disease in CM.     

Oxygen saturation-dependent effects on blood transverse relaxation at low fields

Objective

Blood oxygenation can be measured using magnetic resonance using the paramagnetic effect of deoxy-haemoglobin, which decreases the \(\textit{T}_{2}\) relaxation time of blood. This \(\textit{T}_{2}\) contrast has been well characterised at the \(\textit{B}_{{0}}\) fields used in MRI (1.5 T and above). However, few studies have characterised this effect at lower magnetic fields. Here, the feasibility of blood oximetry at low field based on \(\textit{T}_{2}\) changes that are within a physiological relevant range is explored. This study could be used for specifying requirements for construction of a monitoring device based on low field permanent magnet systems.

Methods

A continuous flow circuit was used to control parameters such as oxygen saturation and temperature in a sample of blood. It flowed through a variable field magnet, where CPMG experiments were performed to measure its \(\textit{T}_{2}\). In addition, the oxygen saturation was monitored by an optical sensor for comparison with the \(\textit{T}_{2}\) changes.

Results

These results show that at low \(\textit{B}_{{0}}\) fields, the change in blood \(\textit{T}_{2}\) due to oxygenation is small, but still detectable. The data measured at low fields are also in agreement with theoretical models for the oxy-deoxy \(\textit{T}_{2}\) effect.

Conclusion

\(\textit{T}_{2}\) changes in blood due to oxygenation were observed at fields as low as 0.1 T. These results suggest that low field NMR relaxometry devices around 0.3 T could be designed to detect changes in blood oxygenation.

     

Examining the Effectiveness of Gamification in Human Computation

Within the human computation paradigm, gamification is increasingly gaining interest. This is because an enjoyable experience generated by game features can be a powerful approach to attract participants. Although potentially useful, little research has been conducted into understanding the effectiveness of gamification in human computation. In this experimental study, we operationalized effectiveness as perceived engagement and user acceptance and examined it by comparing the performance of a gamified human computation system against a non-gamified version. We also investigate the determinants of acceptance and how their effects differ between these two systems. Analysis of our data found that participants experienced more engagement and showed higher behavioral intentions toward the gamified system. Moreover, perceived output quality and perceived engagement were significant determinants of acceptance of the gamified system. In contrast, determinants for acceptance of the non-gamified system were perceived output quality and perceived usability.