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1.
Jens Mller Anne Busch Christian Berens Helmut Hotzel Andreas Burkovski 《International journal of molecular sciences》2021,22(7)
Corynebacterium silvaticum is a newly identified animal pathogen of forest animals such as roe deer and wild boars. The species is closely related to the emerging human pathogen Corynebacterium ulcerans and the widely distributed animal pathogen Corynebacterium pseudotuberculosis. In this study, Corynebacterium silvaticum strain W25 was characterized with respect to its interaction with human cell lines. Microscopy, measurement of transepithelial electric resistance and cytotoxicity assays revealed detrimental effects of C. silvaticum to different human epithelial cell lines and to an invertebrate animal model, Galleria mellonella larvae, comparable to diphtheria toxin-secreting C. ulcerans. Furthermore, the results obtained may indicate a considerable zoonotic potential of this newly identified species. 相似文献
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B. Schönfelder G. Gottstein L. S. Shvindlerman 《Metallurgical and Materials Transactions A》2006,37(6):1757-1771
While the motion of twist boundaries can be readily studied by atomistic simulations with molecular dynamics (MD) under the
action of an elastic driving force, the approach fails for tilt boundaries. This is due to the interaction of the elastic
stress with the grain boundary (GB) structure, which causes plastic strain by GB sliding. A novel concept, the orientation
correlated driving force, is introduced to circumvent this problem. It is shown that this concept can be successfully applied
to the study of the migration of tilt boundaries. The migration behavior of several twist and tilt GBs was investigated. The
transition from low-to high-angle boundaries can be captured, and a structural transition of tilt boundaries was found at
high temperatures, which also affected the migration behavior. The results compare well with experimental results of the motion
high-angle boundaries, but for low-angle boundaries, the agreement is poor.
This article is based on a presentation made in the “Hillert Symposium on Thermodynamics & Kinetics of Migrating Interfaces
in Steels and Other Complex Alloys,” December 2–3, 2004, organized by The Royal Institute of Technology in Stockholm, Sweden. 相似文献
5.
S. Büttgenbach J. Hesselbach R. Tutsch M. Berndt B. Hoxhold K. Schöttler 《Microsystem Technologies》2006,12(7):665-669
Positioning accuracies in the range of a few micrometers and below are necessary for the assembly of active micro-systems. In order to reach these accuracies, an assembly system for sensor guided micro-assembly is developed in the Collaborative Research Centre 516 “Design and manufacturing of active micro-systems”. The combination of a parallel robot with an integrated 3D vision sensor and a micro-gripper enables to reach relative positioning accuracies below 1 μm. 相似文献
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A modified natural surfactant was administered to a patient with life-threatening adult respiratory distress syndrome caused by viral pneumonia. Subsequently, there was a marked improvement in gas exchange. In order to assess the mechanism for improved oxygenation, computed tomography of the lungs was done. Quantitative analysis of the scans taken before and after surfactant administration indicates that improvement in gas exchange was largely due to the expansion of underinflated and collapsed lung areas. Although this is a single case report, it provides insight into the possible beneficial effect of instilled surfactant in severe respiratory distress from viral pneumonia. 相似文献
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Prof. Dr.-Ing. Thorsten Spitta Dipl. Ing. Helmut Schmidpeter 《WIRTSCHAFTSINFORMATIK》2002,44(2):141-150
This paper analyses the characteristics of software houses as service providers. The tasks of internal IT-services are determined from these characteristics and a reporting system for the IT-controlling is outlined. The concept results from the analysis of one of the 25 largest German software houses. The paper concludes with a case study of the fiscal year 2000 IT-controlling report of the above-mentioned firm. 相似文献