腰椎间盘MR高信号区形态及信号强度纵向追踪

目的探讨腰痛患者腰椎间盘高信号区（HIZ）病灶形态及信号强度演变规律。方法回顾性分析2009年1月~2017年1月 腰椎MR检查发现HIZ病灶、并在至少1.5年后复查的27名腰痛患者资料。由2名放射科医师阅读MR图像,目测判断复查时 HIZ病灶形态改变,分为“增大”、“不变”、“缩小”、“消失”。利用ImageJ软件在MR图像上测量初查及复查时HIZ体积及HIZ信 号/脑脊液信号（T2/CSF）比值,对比初查及复查体积及信号强度改变。结果初查可见HIZ累及43个椎间盘,复查时病灶增大 10个（23.3%）,不变22个（51.2%）,缩小9个（20.9%）,消失2个（4.7%）,另可见4个椎间盘出现新的HIZ病灶。ImageJ软件测量 显示,初查及复查HIZ体积相比差异无统计学意义（P>0.05）,复查的T2/CSF 信号比值较初查高（P<0.05）。结论经过平均3年 3月时间观察,腰痛患者椎间盘大部分HIZ病灶形态保持稳定状态,但信号强度增高。     

Study on correlation of mammographic features、pathology and molecular bology of breast infiltrating ductal carcinoma

Objective To investigate the correlation among mammographic features、pathology and molecu-lar biology markers of breast infitrating ductal carcinoma(IDC) tissues.Methods The mammographic features of 93 cases with IDC confirmed by surgery and histopathology were analyzed retrospectively.The mastectomy specimens of the IDC were stained with immunohistochemistry,and the expression of ER、PR、C-erbB-2 were measured.The rela-tionship between the immunohistochemical pathologic results and mammographic features was analyzed.Results A-mong the 93 cases of IDC,ER positive expression was positively correlated with the spiculate margin of breast cancer (P<0.05);C-erbB-2 positive expression was positively correlated(P<0.05).Moreover,ER and PR positive expres-sion showed a significant inverse correlation with the calcifying of breast cancer(P>0.05);ER and PR positive ex-pression was positively correlated with the transfer of lymph(P<0.05);there existed correlation between the positive expression of C-erbB-2 and lymphatic metastasis and pathohistology grade(P<0.05).Conclusion There was a pos-itive correlation among IDC mammography、pathology and the abnormal value of ER、PR and C-erbB-2.The X-ray mammography could reflect the diagnosis value of ER、PR and C-erbB-2 roughly,and thadpractical value in determi-ning prognoses and endocrinotherapy.     

磁共振引导下聚焦超声刀治疗子宫肌瘤的术后评价

目的探讨磁共振引导下聚焦超声刀(HIFU)治疗子宫肌瘤的术后评价。方法选取2017年6月～2018年1月本院收治的子宫肌瘤患者151例,依据随机数字表法分为HIFU组(n=75例)和腹腔镜组(n=76例),腹腔镜组给予腹腔镜下剔除术治疗,HIFU组给予磁共振引导下HIFU治疗,比较两组术后疗效。结果 HIFU组手术时间、术中出血量、住院时间明显低于腹腔镜组,HIFU组手术费用明显高于腹腔镜组,差异有统计学意义(P 0.05);HIFU组术后并发症发生率明显低于腹腔镜组,差异有统计学意义(P 0.05);HIFU组和腹腔镜组术后6个月复发率比较,差异无统计学意义(P 0.05)。结论磁共振引导下HIFU治疗子宫肌瘤的术后疗效良好,且具有创伤小、并发症少、康复快等优点,值得临床作进一步推广。     

乳腺浸润性导管癌X线表现、病理与分子生物学标记关系的研究

目的 探讨乳腺浸润性导管癌（IDC）X线表现、病理与分子生物学标记之间的关系.方法 分析93例经乳腺X线检查、手术及病理证实的IDC患者的X线表现,术后标本应用免疫组化染色测定癌细胞雌激素受体（ER）、孕激素受体（PR）、癌基因（C-erbB-2）的表达情况,并分析与X线表现之间的关系.结果 93例IDC中,癌肿毛刺状边缘与癌细胞ER阳性表达之间呈正相关（P〈0.05）;癌肿钙化与C-erbB-2阳性表达之间呈正相关（P〈0.05）,而与癌细胞ER和PR阳性表达水平之间呈负相关（P〉0.05）;淋巴结转移与癌细胞ER和PR阳性表达之间呈正相关（P〈0.05）,C-erbB-2阳性表达率与有无淋巴结转移及病理组织学分级有关（P〈0.05）.结论 IDC的X线表现、病理与癌细胞ER、PR、C-erbB-2异常表达有一定的相关性,X线表现可以粗略推测ER、PR及C-erbB-2表达情况,对预测IDC淋巴结转移及判断预后有重要意义.     

Study on correlation of mammographic features、pathology and molecular bology of breast infiltrating ductal carcinoma

Objective To investigate the correlation among mammographic features、pathology and molecu-lar biology markers of breast infitrating ductal carcinoma(IDC) tissues.Methods The mammographic features of 93 cases with IDC confirmed by surgery and histopathology were analyzed retrospectively.The mastectomy specimens of the IDC were stained with immunohistochemistry,and the expression of ER、PR、C-erbB-2 were measured.The rela-tionship between the immunohistochemical pathologic results and mammographic features was analyzed.Results A-mong the 93 cases of IDC,ER positive expression was positively correlated with the spiculate margin of breast cancer (P<0.05);C-erbB-2 positive expression was positively correlated(P<0.05).Moreover,ER and PR positive expres-sion showed a significant inverse correlation with the calcifying of breast cancer(P>0.05);ER and PR positive ex-pression was positively correlated with the transfer of lymph(P<0.05);there existed correlation between the positive expression of C-erbB-2 and lymphatic metastasis and pathohistology grade(P<0.05).Conclusion There was a pos-itive correlation among IDC mammography、pathology and the abnormal value of ER、PR and C-erbB-2.The X-ray mammography could reflect the diagnosis value of ER、PR and C-erbB-2 roughly,and thadpractical value in determi-ning prognoses and endocrinotherapy.