复感康治疗小儿反复呼吸道感染26例报告

小儿反复呼吸道感染,发病率较高,治疗无标准方案,我院用复感康治疗26例,现报道如下.     

冠心病伴中度缺血性二尖瓣关闭不全外科治疗的系统评价和Meta分析

目的评价冠状动脉旁路移植术（CABG）同期行二尖瓣置换术（MVR）与单纯行CABG对中度缺血性二尖瓣关闭不全的疗效。方法检索1990年1月2013年8月发表在PubMed,CochraneLibrary,中国期刊全文数据库,万方数据库,维普期刊网等的相关文献,收集国内外关于CABG＋MVR与单纯行CABG对中度缺血性二尖瓣关闭不全外科治疗的对照研究。随机对照研究的质量评价采用Jadad量表,病例对照研究质量评价采用Newcastle．OttawaScale（NOS）标准进行。应用RevMan5．0进行Meta分析。结果共纳入6个研究,包括2个随机对照研究,4个病例对照研究。2个随机对照研究的Jadad评分均为5分,4个病例对照研究的NOS评分均为8分。Meta分析结果显示,两组术后早期死亡率差异无统计学意义[随机对照研究RR=1．69,95％CI（0．28,10．10）,P=-0．57;病例对照研究OR=0．48,95％CI（0．21,1．13）,P=-0．09]。两组1年生存率差异无统计学意义[随机对照研究：RR=1．00,95％CI（0．93,1．08）,P=-0．92;病例对照研究：OR=1．72,95％CI（0．60,4．95）,P=-0．32]。两组5年生存率差异无统计学意义[OR=I．12,95％CI（0．68,1．83）,P=-0．66]。CABG＋MVR组LVEF更高,且差异有统计学意义[MD=1．38,95％CI（0．17,2．59）,P=0．03]。两组术后心功能分级（NYHA）差异有统计学意义[MD一0．85,95％CI（-1．14,-0．56）,P〈0．01]。结论与单纯行CABG相比,CABG＋MVR不能明显提高生存率,但有助于术后心功能恢复及生活质量改善。     

五种材料修复髓室底穿孔临床疗效的对比研究

目的探讨髓室底穿孔较理想的修复材料。方法将146颗髓室底穿孔患牙随机分为LCH组（22颗）、LCR组（20颗）、HA组（20颗）、LGIC组（38颗）和CPC组（46颗），均先行根管治疗，然后穿孔处分别采用LCH、LCR、HA、LGlC和CPC充填修复，并作永久性充填，所有治疗牙均随访观察18～24月。结果5组疗效差异具有极显著性（P〈O．01），LGIC组和CPC组疗效均明显优于LCH组、HA组和LCR组（P〈0．01），LGIC组和CPC组两者疗效差异无显著性（P〉0，05）；LCH组、HA组和LCR组三者问疗效差异无显著性（P〉0．05）。结论LGIC、CPC是修复髓室底穿孔较理想的修复材料。     

上颌窦提升术在种植修复中的临床应用

目的探讨上颌窦提升术在上颌磨牙缺失种植修复术中的应用及疗效。方法对上颌磨牙后区牙槽骨严重吸收导致骨量不足的15例患者运用上颌窦提升术、人工骨植入术并同期植入BEGO两段式种植体17枚,其中上颌窦内提升术12例,植入种植体13枚;上颌窦外提升术3例,植入种植体4枚。全部病例术后1周和3、6、9个月摄曲面体层片检查种植体稳定性及人工骨与种植体愈合情况。结果17枚种植体无一枚感染及松动,无上颌窦炎症,术后6～9个月X线示人工骨粉均已改建成新骨,种植体周围无阴影。结论上颌窦提升术及同期种植体植入术方法可靠,具有良好疗效,可显著扩大牙种植体植入术适应证。     

Combined use of transmyocardial laser revascularization and endothelial progenitor cells enhances neovascularization and regional contractility in a canine model of ischemic hearts

The purpose of this study was to determine the combined effect of transmyocardial laser re- vascularization （TMLR） and the implantation of endothelial progenitor cells （EPCs） on cardiac function of ischemic hearts in canines. The left anterior descending artery （LAD） was occluded to establish the canine model of acute myocardial infarct （AMI）. Four weeks later, the animals were randomly divided into four groups： TMLR group, in which transmyocardial laser-induced channels were established at the ischemic region; EPCs＋TMLR group, in which EPCs were locally transplanted into laser-induced chan- nels at the ischemic region; EPCs group, in which the EPCs were injected into the ischemic region; con- trol group, in which the AMI animals received neither TMLR nor EPCs. The peripheral blood （50 mL） was sampled in all groups. Mononuclear cells from the peripheral blood were separated and cultured to obtain spindle-shaped attaching （AT） cells in vitro. AT cells were labeled with 1, 1 ＇-dioctadecyl-1 to 3,3, 3＇,3＇-tetramethyl-indocarbocyanine perchlorate （DiI） before injecting into the laser-induced channels or ischemic region. Four weeks after the first operation, TMLR was performed in the TMLR group and EPCs＋TMLR group, and at the same time, the EPCs originating from the AT cells were mixed with cal- cium alginate （CA）. Then the EPCs-CA composites were implanted into myocardial channels induced by laser in the EPCs＋TMLR group, and into the myocardial infarct area in the EPCs group. All dogs underwent echocardiography at second month after LAD occlusion. Finally the samples of myocardium around the LAD were subjected to histochemical and immunohistologic examinations. The results showed there was no significant difference in the diameter of left atrium and ventricle before treatment among all groups （P〉0.05）. Eight weeks after modeling, the regional contractility in the LAD territory in the EPCs＋TMLR group was increased as compared with control group and TMLR group, but there was no significant difference between control group and TMLR group. Neoangiogenesis was observed in the EPCs＋TMLR group, and the fibrosis was seen in the TMLR group. There was no significant dif- ference in neoangiogenesis around the channels induced by laser among EPCs＋TMLR, EPCs and TMLR groups. It was concluded that TMLR combined with EPCs could improve the regional and global cardiac function in AMI, and augment neovascularizaiton in channels of ischemic myocardium induced by laser.     

社区老年人口腔疾病流行病学特征

在我国现阶段的老年人口已经超过了11%〔1〕,老龄化程度非常高,随着时间的推移,问题会日益严重。我国老年人的口腔问题由于经济条件、生活习惯等因素的影响,使得其远远高于世界平均水平〔2〕。而且老年人的口腔疾病较为复杂,经常发生多种口腔疾病并存的情况,再加上老年人自身的生理特点,治疗口腔疾病的难度颇高。本文以社区为基础对老年人口     

先天性冠状动脉瘘的诊断与治疗(附34例报告)

目的:总结分析34例先天性冠状动脉瘘(CAF)的临床诊断治疗与外科手术方法。方法:回顾性分析应用超声心动图、64层螺旋CT、选择性冠状动脉造影等检查确诊的34例CAF患者的临床资料,其中24例为单纯性CAF,10例合并其他心脏外科疾病。结果:34例中5例直接行动脉瘘切线缝合术,其余29例均在体外循环直视下行瘘口修补并同时矫治合并心脏疾病。心腔内发现2瘘口1例,4瘘口1例,其他均为单一瘘口。所有患者术毕效果明显,无一例死亡,超声心动图复查均无残余瘘存在。22例随访0.5~3年无死亡及并发症发生。结论:64层螺旋CT检查可准确显示各种CAF的起源、行程、引流部位及并发异常,显示冠状动脉近段管腔的形态及一些较大冠状动脉瘘,是一种较为理想的无创性诊断CAF的影像方法。CAF明确诊断后,及时行外科手术治疗安全可靠,少数患者可行介入治疗。