三维光弹性法对不同长度和直径桩核的应力分析

目的：对比不同长度和直径的桩核受力后应力分布情况。方法：根据桩的长短、粗细将实验分成4组，通过垂直和斜向加载，采用三维光弹性应力冻结法，经模型切片观察计算出模型各测点的最大剪应力。结果：桩的直径增加根尖区最大剪应力相应增高，桩核交界处和核与根面交界面最大剪应力明显增高。桩的长度增加，应力分布更为均匀。结论：从抗力固位角度出发有一定长度的粗细合适的柱形桩核较为理想。     

三维光弹性法对不同长度和直径桩核的应力分析

目的对比不同长度和直径的桩核受力后应力分布情况.方法根据桩的长短、粗细将实验分成4组,通过垂直和斜向加载,采用三维光弹性应力冻结法,经模型切片观察计算出模型各测点的最大剪应力.结果桩的直径增加根尖区最大剪应力相应增高,桩核交界处和核与根面交界面最大剪应力明显增高.桩的长度增加,应力分布更为均匀.结论从抗力固位角度出发有一定长度的粗细合适的柱形桩核较为理想.     

不同长度和直径桩核的三维光弹性应力分析

目的 对比不同长度和直径的桩核受力后应国分布情况。方法 根据桩的长短、粗细胞将实验分成四组,通过垂直和斜向加载,采用三维光弹性应力冻结法,经模型切片观察计算出模型各测点的最大剪应力。结果 桩的直径增加根尖区最大剪应力相应增高,桩核交界处和核与根面交界面最大剪应力的明显增高。桩的长度增加,应力分布更为均匀。结论 从抗力固位角度出发有一定和蔗的粗细合适的柱形桩核较为理想。     

Three-dimensional photoelasticity analysis of Nitinol Patellar Concentrator for treating patellar fractures

ood results are got when the patellar fractures aretreated by Nitinol Patellar Concentrator (NT-PC )L','],and the NT-PC is appraised to .be the idealest one amongall the methods on treating patellar fractu.,L3]. The objective of our experiment is to study the distribution of stressin patellar when it is fi-cated by NT-PC, which is made ofNi-Ti shape memory alloy. The biomechanical elements ofit in treating codrinuted patellax fractUres and distal polecoconuted patellar fractIJres is il…     

新抗疟化合物的临床前毒性研究——Ⅴ.5-对氟苯氧基伯喹柠檬酸盐的急性、亚急性毒性观察(1)

磷酸伯氨喹啉(简称伯喹)是间日疟治疗中迄今为止,视为毒性最小、效果最好的抗复发药。即使这样,伯喹仍有疗程过长,毒性较大等缺点,临床应用受到一定的限制。为此,多少年来国内外学者致力于伯喹结构的改造和构效关系的探索,借以寻找高效低毒的新抗复发药,已成为当前抗疟药研究中     

阜宁县医院产科卡介苗接种质量分析

为了掌握我县医院产科卡介苗（BCG）接种效果,以便提高和保持高质量的BCG接种工作,我们于1997年9月随机抽取了1所县级医院、12所乡级医院,对在这些医院产科出生和生后24小时内接种过BCG、且年龄为0～l岁的健康儿童293人,进行了BCG纯蛋白衍化物（PPD）试验。PPD试剂由卫生部上海生物制品研究所供给。接种PPD试剂72小时后观察结果,结果判断：局部硬结平均直径＜5mm者,或仅有红晕而无硬结反应者为阴性反应;局部硬结平均直径≥5mm者为阳性反应。结果显示,卡痕阳性率（≥2mm）为96．20／（282／293）,PPD试验阳转率为80．90（…     

小儿遗尿治验

小儿遗尿治验张林春，刘志忠小儿遗尿症是临床常见而在治疗中收效较慢的疾病。我用温阳补气，固涩健脾法治疗收到迅速的效果．特作以下报导。患者马某某，女，１３岁，本院家属。患儿有遗尿史，重感冒之后病情加重。如听到水声，或者跑步，笑，上下楼梯，咳嗽均出现遗尿。...     

补脾胃泻阴火升阳汤加减治疗脾虚阴火型2型糖尿病的临床观察

目的探究补脾胃泻阴火升阳汤加减治疗脾虚阴火型2型糖尿病(T2DM)的临床疗效。方法选取天津市津南区葛沽镇卫生院2017年9月至2020年9月确诊的2型糖尿病患者中选取中医辩证为脾虚阴火型患者96例,采用随机数字表法分为对照组和观察组各48例。对照组口服西药阿卡波糖片、盐酸二甲双胍片治疗。观察组在对照组基础上加用补脾胃泻阴火升阳汤加减口服治疗,两组均治疗3个月。比较两组治疗3个月时的临床疗效,同时分别于治疗前、治疗3个月时,检测两组患者的空腹血糖(FPG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)水平,计算胰岛素抵抗指数(HOMA-IR)、胰岛β细胞功能指数(HOMA-β)。结果观察组治疗总有效率高于对照组(P<0.05);治疗3个月时,两组FPG、HbA1c、FINS水平均较治疗前降低,且观察组显著低于对照组(P<0.05);治疗3个月时,两组HOMA-IR较治疗前降低,HOMA-β较治疗升高,且观察组HOMA-IR显著低于对照组,HOMA-β显著高于对照组(P<0.05)。结论补脾胃泻阴火升阳汤加减用于脾虚阴火型T2DM的治疗,可以获得更为理想的降糖效果,可提高临床疗效,且患者胰岛功能改善更好。     

苯磺酸氨氯地平口腔崩解片的生物等效性研究

采用单剂量随机交叉设计评价18名健康受试者口服苯磺酸氨氯地平口腔崩解片(受试制剂)和片剂(参比制剂)的生物等效性,用LC-MS/MS法测定血浆中药物浓度.结果表明,受试制剂和参比制剂的主要药动学参数:tmax为(6.1±0.7)h和(6.0±0.0)h,cmax为(7.5±2.9)和(7.6±2.5)ng/ml,t1/2为(34.8±12.3)和(32.5±7.1)h,AUC0-1为(224.6±68.3)和(236.5±81.0)ng·h·ml-1,AUC0-∞为(262.3±89.0)和(274.6±93.8)ng·h·ml-1.受试制剂的相对生物利用度为(96.0±10.4)%,显示两种制剂生物等效.     

Comparative study of various internal fixation methods for treating patellar fractures by three-dimensional photoelasticity

Objective: To compare the biomechanical basis of 3 different internal fixation methods: nitinol patellar concentrator (NT-PC),tension band and wire circle in treating patellar fractures. Methods:The epoxy resin three dimensional photoelasticity patellar models were made by precise moulding, and were fixated by nitinol patellar concentrator (NT-PC) , tension band and wire circle respectively. The patellar models with frozen stress stripes were put into the polarized light field and the stress distributions were compared. As for the model fixated by NT-PC, by dividing layer, photographing and tracing, we used the iterative method to calculate the stress value of every internal node of the epoxy resin patellar model, and the character of stress was analyzed. Results:An overall stress field was yielded when the patellar model was fixated by NT-PC, and the stripes were more than that of tension band model and wire circle model, which have only few stress stripes in the fixated layers. Further analysis indicated that there were continuous fixated stresses in the facies articularis and distal pole of patella, and the character of stresses produced by NT-PC were mainly in longitudinal direction, then in transverse direction. The shearing stresses were small. Conclusion: The initiative and continuous memorial stress of NT-PC and its overall stress distribution character are the essence of NT-PC distinguished with tension band and wire circle in treating patellar fractures. The stress character produced by NT-PC is good for the stability of fracture site and prompts fracture healing.