腹腔镜下完整结肠系膜切除术对近期肝肠循环和机体免疫的影响

目的：探讨腹腔镜下完整结肠系膜切除术(CME)对近期肝肠循环和机体免疫的影响。方法：按照随机数字表法将2020年3月～2021年11月九江市第一人民医院收治的63例择期行腹腔镜下CME术的患者分为三组,术后对照组21例予以常规药物治疗,观察1组21例在对照组基础上于围手术期给予维生素D3治疗,观察2组21例在对照组基础上予以围手术期及术后3 w予以双岐杆菌三联活菌治疗。观察3组免疫指标、炎症水平、胆红素及维生素D3水平、并发症发生率。结果：入院时3组患者免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、免疫球蛋白A(IgA)水平对比差异无统计学意义(P>0.05);治疗4 w后3组患者IgG、 IgM、IgA均比治疗前升高,但观察1组和2组高于对照组,差异均有统计学意义(P<0.05);观察1组和2组对比差异无统计学意义(P>0.05)。入院时3组患者白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)水平对比差异无统计学意义(P>0.05);治疗4 w后3组患者IL-6、TNF-α、CRP水平均比治疗前降低,但观察1组和2组低于对照组...     

双通道吻合术与Roux-en-Y吻合术在腹腔镜近端胃癌根治术中的近期临床疗效对比

目的 探讨腹腔镜近端胃癌根治术中双通道消化道重建方式的近期临床效果.方法 回顾性分析本院2016年1月至2018年12月收治的57例近端胃癌患者的临床资料,按照手术方式不同分为双通道组(空肠间置双通道吻合,n=27)和全胃组(全胃切除Roux-en-Y吻合,n=30).比较两组手术指标、住院时间、住院费用、近期并发症发生率及术后不同时间体质量、血红蛋白水平、白蛋白水平.结果 两组术中失血量、住院时间、住院费用、近期并发症发生率、体质量及白蛋白比较差异无统计学意义.双通道组手术时间为(249.6±38.8)min,短于全胃组的(278.5±46.2)min,淋巴结数目为(18.4±3.6)个,少于全胃组的(23.3±8.5)个,胃肠道生活质量指数评分为(102.0±6.5)分,高于全胃组的(84.9±8.2)分,差异均具有统计学意义(P<0.05).术后1、3、6个月,双通道组血红蛋白水平高于全胃组,差异有统计学意义(P<0.05).结论 腹腔镜近端胃癌根治术采用双通道吻合的消化道重建方式具有良好的改善贫血效果,患者术后生活质量更好,在严格把握适应证的情况下可推广开展.     

腹腔镜下头尾侧联合入路治疗右半结肠癌的疗效分析

Objective To explore the short-term clinical efficacy of laparoscopic-assisted right hemicolectomy with head-tail approach. Methods The clinical data of 60 patients with right colon cancer were retrospectively analyzed, and they were divided into observation group (head-tail approach) and control group (medial-to-lateral approach). Operation time, numbers of lymph nodes, intraoperative blood loss, mesangial integrity, postoperative pain VAS score, postoperative first exhaust time (d), intraoperative abdominal drainage, postoperative hospital stays, CEA and CA19-9 levels and postoperative complication were compared between the two groups. Results In observation group, intraoperative blood loss was less than the control group (48.33±25.88 ml vs. 68.33±44.11 ml), number of lymph nodes was more than the control group (23.90±7.32 vs. 18.30±6.43), mesangium integrity was better than the control group (1.73± 0.45 vs. 1.27±0.45) (P<0.05). There was no significant difference in postoperative hospital stays, first exhaust time, postoperative pain score, postoperative abdominal drainage, CEA and CA199 levels or short-term complications between two groups (P>0.05). Conclusion Laparoscopic-assisted right hemicolectomy is safe and feasible with a head-tail approach. © 2020, CHINA RESEARCH ON PREVENTION AND TREATMENT. All rights reserved.