Cardiac risk in surgery. A review and guidelines for risk evaluation and reduction of cardiac risk in general surgery

We report herein the phenotypic and functional analysis of human bone marrow and thymus derived early T cells. Commitment to T cell lineage is acquired during CD7 antigen expression by CD34+ precursors in human bone marrow and before thymus colonization. Early thymocytes show similar phenotypic characteristics as bone marrow T cells. They rapidly acquire CD4 before the dual expression of CD4 and CD8. Their expansion and differentiation is regulated by two major factors: thymic stroma and cytokines produced by these stroma cells or by thymocytes themselves. Among cytokines, IL1 and sCD23 produced by thymic epithelial cells support in vitro early T cell development.     

Planning considerations for domestic replacement satellites

Several domestic satellite systems have been more than 10 years in operation. During this time, the world has experienced a dramatic growth in communication. While the demand for more telephony and data circuits and television channels is still on the rise, new methods of signal transmission and circuit compression have been developed which may balance or reduce the need for more satellite trunk capacity. And while whole national networks are converting to digital transmission, new transmission media like optical fibre, are finding application, and may take over some of the heavy traffic routes previously carried by satellite. On the other side, business data communication between roof-top terminals, thin route traffic to remote users, television distribution by direct satellite broadcasting are becoming more popular and satellite land mobile communication may soon be a reality. Thus the domestic satellite's role appears to be slowly changing towards thin route and mobile traffic and DBS-type distribution and perhaps even radio position determination. System planners are adapting to the new trends in satellite communication and are trying to accommodate the various service payloads on a single satellite. This article discusses some aspects of the emerging multi-purpose domestic satellite, which carries fixed and mobile services, TV direct broadcasting and radio position determination, in view of network digitalization, network expansion, circuit compression, synchronization. The discussion centres on transponder supply and demand, satellite replenishment, K_u-band vs. C-band for TV direct satellite broadcasting, choice of modulation/multiple access for mobile communication, and expected accuracy in radio position determination.     

Evolutionary Algorithms for Quantum Computers

In this article, we formulate and study quantum analogues of randomized search heuristics, which make use of Grover search (in Proceedings of the 28th Annual ACM Symposium on Theory of Computing, pp. 212–219. ACM, New York, 1996) to accelerate the search for improved offsprings. We then specialize the above formulation to two specific search heuristics: Random Local Search and the (1+1) Evolutionary Algorithm. We call the resulting quantum versions of these search heuristics Quantum Local Search and the (1+1) Quantum Evolutionary Algorithm. We conduct a rigorous runtime analysis of these quantum search heuristics in the computation model of quantum algorithms, which, besides classical computation steps, also permits those unique to quantum computing devices. To this end, we study the six elementary pseudo-Boolean optimization problems OneMax, LeadingOnes, Discrepancy, Needle, Jump, and TinyTrap. It turns out that the advantage of the respective quantum search heuristic over its classical counterpart varies with the problem structure and ranges from no speedup at all for the problem Discrepancy to exponential speedup for the problem TinyTrap. We show that these runtime behaviors are closely linked to the probabilities of performing successful mutations in the classical algorithms.     

UR: SMART–A tool for analyzing social media content

Information Systems and e-Business Management - The digital transformation, with its ongoing trend towards electronic business, confronts companies with increasingly growing amounts of data which...     

Television Sound Subcarrier Transmission in Space Communication

In a nonideal transmission enviromnent, the transmission of video sound in the form of an FM subcarrier above the video baseband causes interactions between video and sound subcarrier which result in signal distortion. The degree of distortion depends on the type of channel impairments and the selection of transmission parameters. While the fidelity of the video signal can be preserved by mainly limiting the subcarrier level, the quality of the audio channel can be optimized by choosing the right subcarrier frequency. It can be shown that for a given video-carrier-to-noise ratio, subcarrier power below video signal power, and for given system impairments, there exists an optimum subcarrier location which provides a maxinum audio-signal-to-noise ratio.     

Radio fluorination and positron emission tomography (PET) as a new approach to study the in vivo distribution and elimination of the advanced glycation endproducts N epsilon-carboxymethyllysine (CML) and N epsilon-carboxyethyllysine (CEL).

After synthesis of fluorine-18 labelled analogues by [18F]fluorobenzoylation at the alpha-amino group, biodistribution and elimination of individual advanced glycation endproducts, namely N epsilon-carboxymethyllysine and N epsilon-carboxyethyllysine, were studied in comparison to lysine in rats after intravenous injection using positron emission tomography (PET). The [18F]radiofluorinated amino acids were fast distributed via the blood, followed by a rapid excretion through the kidneys. Elimination kinetics were similar for both AGEs and lysine. For CML and CEL, but not for lysine, a temporary liver accumulation could be observed, which was not connected with any metabolisation or enterohepatic circulation. No further accumulation in any tissues was observable, indicating that increased tissue levels of CML or CEL, which have been described for certain disorders, are exclusively derived from endogenous origin and should not depend on a dietary intake. However, under uremic conditions, an impaired kidney function might result in a significant increase of the AGE-load of blood and tissues. PET based on 18F-labelled AGEs proved to be a promising tool to elucidate the physiological fate of post-translationally modified amino acids and to clarify the role of AGEs as possible "glycotoxins".     

Evaluation and accuracy assessment of high‐resolution IFSAR DEMs in low‐relief areas

The use of digital elevation models from remotely sensing systems has been restricted in the past to high‐relief areas due to the lack of appropriate resolution and accuracy to map micro‐relief variability in low relief areas. Interferometric synthetic aperture radar, a new technology that provides detailed elevation models from remotely sensed data, is evaluated. Main characteristics of this data are highlighted. Accuracy assessment is tested in detail for two high‐resolution acquisition modes using higher accuracy sources of data. The accuracy results using the root mean square (rms) error were better than expected according to mission specifications. However, at the checkpoint locations where the signal backscatter generates an elevation measure, the accuracy depends considerably upon the site‐specific surface characteristics, such as the land use, above ground biomass, adjacent forest areas and infrastructure features located within surrounding pixels.     

TVRO Antenna Size, Ku Band Versus C Band

At this point in time, with the advent of high powered Ku band direct broadcast satellites (DBSs) and the ever increasing requirement for TV via satellite, it is safe to say that satellite rooftop receiving antennas will soon shrink in size. This will be true for DBS systems operating in the Ku DBS band, since Ku band EIRP has been increased considerably over C band EIRP. It will not necessarily be true for Ku band satellite systems operating in the broadcast satellite service band, where maximum power flux density, and therefore EIRP, is limited.     

Das Dekompositionsmodell nach Wand und Weber im Kontext der Prozessmodellierung

Whereas the benefits of decomposing process models are obvious, the question what actually characterizes a ??good?? decomposition of a business process model has been given little attention to date. In addition, the process of decomposition itself is considered as being an ??art?? in literature. Our approach for achieving a ??good?? decomposition is Wand and Weber??s decomposition model for information systems. As a first step in our investigation we aim to explore in how far the decomposition model can be adapted for business process modelling at all. The potential this model might bear for evaluating decompositions of process models has been promoted in literature quite often, while a corresponding investigation is still missing. We address this gap by the following research. In the long term, we intend to establish guidelines for decomposing business process models in a structured way.     

Novel rhenium complexes derived from alpha-tropanol as potential ligands for the dopamine transporter

A series of rhenium complexes was synthesized as model compounds for the corresponding radioactive technetium-99m complexes for preliminary biological investigations. In a '3 + 1' mixed-ligand approach the tropanol molecule was linked with the metal core through a omega-mercaptoester group as monodentate ligand. Bis(thioethyl)sulphide was used as the tridentate dithiol ligand to block the remaining free coordination sites. The omega-mercaptoesters were synthesized via the trityl-protected precursors. Binding tests on the cloned human dopamine transporter revealed moderate binding affinities for some of the prepared compounds. The complexes were characterised by X-ray and the lipophilicity as well as pKa values were determined.