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1.
Optimal control (OC) methodology is used to develop a control policy for a batch-operated solar sludge dryer with ventilation as the dominant control. Batch performance criteria and instantaneous optimization criteria are developed for two economic environments: quota limited and capital limited. The general formulation, as well as simplifications resulting from the multiplicative form of the evaporation (drying) rate model, are presented. The multiplicative form results in a single constant number, called here “control intensity,” which is used to guide the on-line control decisions. These decisions turn out to be independent of the dry solids content (DSC) of the sludge. Further simplification, by assuming a strictly constant weather, is used to demonstrate the general effects of the economic and physical (weather) environment on the solution.
The OC approach is used to address, via simulation under realistic weather conditions, several design, operation, and pricing problems. In particular, the following have been considered: sizing of the ventilation fans, determination of a fair fee for sludge disposal, finding the best final DSC, and evaluating the effect of the price of electricity. Regarding the particular location represented by the data, it has been shown that the installed capacity of the ventilation fans should be increased and that there seems to be sufficient economic incentive for solar drying. 相似文献
The OC approach is used to address, via simulation under realistic weather conditions, several design, operation, and pricing problems. In particular, the following have been considered: sizing of the ventilation fans, determination of a fair fee for sludge disposal, finding the best final DSC, and evaluating the effect of the price of electricity. Regarding the particular location represented by the data, it has been shown that the installed capacity of the ventilation fans should be increased and that there seems to be sufficient economic incentive for solar drying. 相似文献
2.
Aleksandra A. Ageeva Ilya M. Magin Alexander B. Doktorov Victor F. Plyusnin Polina S. Kuznetsova Alexander A. Stepanov Alexander A. Alekseev Nikolay E. Polyakov Tatyana V. Leshina 《International journal of molecular sciences》2021,22(12)
The study of the L- and D-amino acid properties in proteins and peptides has attracted considerable attention in recent years, as the replacement of even one L-amino acid by its D-analogue due to aging of the body is resulted in a number of pathological conditions, including Alzheimer’s and Parkinson’s diseases. A recent trend is using short model systems to study the peculiarities of proteins with D-amino acids. In this report, the comparison of the excited states quenching of L- and D-tryptophan (Trp) in a model donor–acceptor dyad with (R)- and (S)-ketoprofen (KP-Trp) was carried out by photochemically induced dynamic nuclear polarization (CIDNP) and fluorescence spectroscopy. Quenching of the Trp excited states, which occurs via two mechanisms: prevailing resonance energy transfer (RET) and electron transfer (ET), indeed demonstrates some peculiarities for all three studied configurations of the dyad: (R,S)-, (S,R)-, and (S,S)-. Thus, the ET efficiency is identical for (S,R)- and (R,S)-enantiomers, while RET differs by 1.6 times. For (S,S)-, the CIDNP coefficient is almost an order of magnitude greater than for (R,S)- and (S,R)-. To understand the source of this difference, hyperpolarization of (S,S)-and (R,S)- has been calculated using theory involving the electron dipole–dipole interaction in the secular equation. 相似文献
3.
Ilya Malyanov Brian J. d'Auriol Sungyoung Lee 《Journal of Visual Languages and Computing》2013,24(4):223-233
The visualization process is a transformation of information content into knowledge via a visual representation. Visualization experience, proposed herein, reflects human sensations arising during the visualization process. It provides a basis in which to objectively measure and evaluate human participation in the visualization process; and thereby provides methods of control. Visualization experience modeling allows leveraging on the natural environment to augment understanding, therefore improve decision making. The application emphasis in this paper is on the theoretical development of visualization experience in the visualization process as applied to Ambient Assisted Living and Clinical Decision Support Systems. 相似文献
4.
We consider the problem of approximately integrating a Lipschitz function f (with a known Lipschitz constant) over an interval. The goal is to achieve an additive error of at most ε using as few samples of f as possible. We use the adaptive framework: on all problem instances an adaptive algorithm should perform almost as well
as the best possible algorithm tuned for the particular problem instance. We distinguish between
and
, the performances of the best possible deterministic and randomized algorithms, respectively. We give a deterministic algorithm
that uses
samples and show that an asymptotically better algorithm is impossible. However, any deterministic algorithm requires
samples on some problem instance. By combining a deterministic adaptive algorithm and Monte Carlo sampling with variance reduction,
we give an algorithm that uses at most
samples. We also show that any algorithm requires
samples in expectation on some problem instance (f,ε), which proves that our algorithm is optimal. 相似文献
5.
We obtain subquadratic algorithms for 3SUM on integers and rationals in several models. On a standard word RAM with w-bit words, we obtain a running time of
. In the circuit RAM with one nonstandard AC
0 operation, we obtain
. In external memory, we achieve O(n
2/(MB)), even under the standard assumption of data indivisibility. Cache-obliviously, we obtain a running time of
. In all cases, our speedup is almost quadratic in the “parallelism” the model can afford, which may be the best possible.
Our algorithms are Las Vegas randomized; time bounds hold in expectation, and in most cases, with high probability. 相似文献
6.
Presented is a method of smooth sliding mode control design to provide for an asymptotic second‐order sliding mode on the selected sliding surface. The control law is a nonlinear dynamic feedback that in absence of unknown disturbances provides for an asymptotic second‐order sliding mode. Application of the second‐order disturbance observer in a combination with the proposed continuous control law practically gives the second‐order sliding accuracy in presence of unknown disturbances and discrete‐time control update. The piecewise constant control feedback is “smooth” in the sense that its derivative numerically taken at sampling rate does not contain high frequency components. A numerical example is presented. 相似文献
7.
Vitaly Shubin Yury Shelygin Sergey Achkasov Oleg Sushkov Ilya Nazarov Alexey Ponomarenko Iuliia Alimova Anna Loginova Aleksey Tsukanov 《International journal of molecular sciences》2022,23(13)
The aim of this study was to determine the characteristics of Russian patients with microsatellite instability (MSI) tumors. MSI in the tumor was determined in 514 patients with colon cancer using PCR and subsequent fragment analysis for five markers (NR21, NR24, BAT25, BAT26, and NR27). In the presence of microsatellite instability, the mismatch repair (MMR) system genes were examined using the NGS and MLPA methods to establish the diagnosis of Lynch syndrome. The overall frequency of MSI tumors was 15%: at stage I—19% (9/48), at stage II—21% (44/213), at stage III—16% (26/160), and at stage IV—2% (2/93). Patients with MSI tumors differed in the age of diagnosis, tumor localization, time of cancer recurrence, and stage of the disease. The overall and disease-free survival of patients whose tumors had MSI status was higher than that of patients with microsatellite-stable status, p = 0.04 and p = 0.02, respectively. Analysis of overall and disease-free survival of patients with Lynch syndrome and patients with sporadic colon cancer, but with MSI status, did not reveal significant differences, p = 0.52 and p = 0.24, respectively. The age of patients with Lynch syndrome was significantly younger than that of patients with sporadic colon cancer whose tumors had MSI status (p < 0.001). 相似文献
8.
Stanislav S. Lazarev Ulyana V. Shevchenko Vyacheslav A. Dyachuk Ilya G. Vyatchin 《International journal of molecular sciences》2022,23(14)
We describe the development of a preparative method to isolate molluscan catch muscle, calponin. This method is based on the ability of calponin to interact with actin in a temperature-dependent manner. After extracting thin filaments, as previously described, the extract was ultracentrifuged at 2 °C. While other surface proteins of thin filaments co-precipitated with actin, calponin, along with some minor contaminants, remained in the supernatant. Calponin was purified through cation-exchange chromatography. The yield of pure protein was four-fold higher than that achieved through high-temperature extraction. To evaluate functionally isolated proteins, we determined the effect of calponin on Mg2+-ATPase activity of hybrid and non-hybrid actomyosin. The degree of ATPase inhibition was consistent with previously published data but strongly dependent on the environmental conditions and source of actin and myosin used. Furthermore, at low concentrations, calponin could induce the ATPase activity of hybrid actomyosin. This result was consistent with data indicating that calponin can modulate actin conformation to increase the relative content of “switched on” actin monomers in thin filaments. We assume that calponin obtained by the isolation method proposed herein is a fully functional protein that can both inhibit and induce the ATPase activity. 相似文献
9.
Quanlong Yang Sergey Kruk Yuehong Xu Qingwei Wang Yogesh Kumar Srivastava Kirill Koshelev Ivan Kravchenko Ranjan Singh Jiaguang Han Yuri Kivshar Ilya Shadrivov 《Advanced functional materials》2020,30(4)
All‐dielectric metasurfaces have become a new paradigm for flat optics as they allow flexible engineering of the electromagnetic space of propagating waves. Such metasurfaces are usually composed of individual subwavelength elements embedded into a host medium or placed on a substrate, which often diminishes the quality of the resonances. The substrate imposes limitations on the metasurface functionalities, especially for infrared and terahertz frequencies. Here a novel concept of membrane Huygens' metasurfaces is introduced. The metasurfaces feature an inverted design, and they consist of arrays of holes made in a thin membrane of high‐index dielectric material, with the response governed by the electric and magnetic Mie resonances excited within dielectric domains of the membrane. Highly efficient transmission combined with the 2π phase coverage in the freestanding membranes is demonstrated. Several functional metadevices for wavefront control are designed, including beam deflector, a lens, and an axicon. Such membrane metasurfaces provide novel opportunities for efficient large‐area metadevices, whose advanced functionality is defined by structuring rather than by chemical composition. 相似文献
10.
Erinija Pranckeviciene Sergey Hosid Indiras Maziukas Ilya Ioshikhes 《International journal of molecular sciences》2022,23(9)
Nucleosomes are basic units of DNA packing in eukaryotes. Their structure is well conserved from yeast to human and consists of the histone octamer core and 147 bp DNA wrapped around it. Nucleosomes are bound to a majority of the eukaryotic genomic DNA, including its regulatory regions. Hence, they also play a major role in gene regulation. For the latter, their precise positioning on DNA is essential. In the present paper, we describe Galaxy dnpatterntools—software package for nucleosome DNA sequence analysis and mapping. This software will be useful for computational biologists practitioners to conduct more profound studies of gene regulatory mechanisms. 相似文献