帕金森病交感神经皮肤反应的临床研究

Objective To assess the value of detecting sympathetic skin response (SSR) in the diagnosis of autonomic dysfunction in patients with Parkinson disease (PD). Methods SSR measurement was performed in 47 PD patients and 20 healthy control subjects and the results were compared. The SSR was also comparatively analyzed between patients with and those without autonomic dysfimction. Results Compared with the healthy controls, the PD patients showed significantly lowered mean amplitude (2.56±1.47 vs 1.87±0.26, P<0.05) and prolonged latency (1.42±0.29 vs 1.55± 0.18, P<0.05) of the SSR in the upper limbs, with also lowered mean amplitude (0.76±0.39 vs 0.49±0.21, P<0.05) and prolonged latency (2.04±0.27 vs 2.13±0.16, P<0.05) in the lower limbs. Compared with the PD patients without autonomic dysfunction, those having autonomic dysfunction showed significantly lowered mean amplitude (1.89±0.33 vs 1.75±0.21, P<0.05) and prolonged latency (1.53±0.15 vs 1.56±0.17, P<0.05) of SSR in the upper limbs and lowered mean amplitude (0.51±0.17 vs 0.46±0.20,P<0.05) and prolonged latency (2.08±0.24 vs 2.17±0.18, P<0.05) in the lower limbs. Conclusion The results of SSR measurements are consistent with the clinical manifestations of the PD patients. SSR can be of value in the diagnosis of autonomic nerve dysfunction in PD.     

经眼上静脉途径栓塞海绵窦区硬脑膜动静脉瘘

目的 探讨经眼上静脉途径栓塞治疗海绵窦区硬脑膜动静脉瘘的临床效果. 方法 对27例海绵窦区硬脑膜动静脉瘘患者行经眼上静脉途径栓塞治疗,通过脑血管造影及临床随访来评价临床疗效. 结果 术后即刻造影示瘘口完全闭塞15例,瘘口处血流速度明显减慢12例.11例患者术后眼球水肿一过性加重.随访3月～4年,临床症状消失17例,症状明显缓解10例. 结论 经眼上静脉途径栓塞治疗海绵窦区硬脑膜动静脉瘘对部分患者是一种有效的治疗方法 .     

帕金森病交感神经皮肤反应的临床研究

Objective To assess the value of detecting sympathetic skin response (SSR) in the diagnosis of autonomic dysfunction in patients with Parkinson disease (PD). Methods SSR measurement was performed in 47 PD patients and 20 healthy control subjects and the results were compared. The SSR was also comparatively analyzed between patients with and those without autonomic dysfimction. Results Compared with the healthy controls, the PD patients showed significantly lowered mean amplitude (2.56±1.47 vs 1.87±0.26, P<0.05) and prolonged latency (1.42±0.29 vs 1.55± 0.18, P<0.05) of the SSR in the upper limbs, with also lowered mean amplitude (0.76±0.39 vs 0.49±0.21, P<0.05) and prolonged latency (2.04±0.27 vs 2.13±0.16, P<0.05) in the lower limbs. Compared with the PD patients without autonomic dysfunction, those having autonomic dysfunction showed significantly lowered mean amplitude (1.89±0.33 vs 1.75±0.21, P<0.05) and prolonged latency (1.53±0.15 vs 1.56±0.17, P<0.05) of SSR in the upper limbs and lowered mean amplitude (0.51±0.17 vs 0.46±0.20,P<0.05) and prolonged latency (2.08±0.24 vs 2.17±0.18, P<0.05) in the lower limbs. Conclusion The results of SSR measurements are consistent with the clinical manifestations of the PD patients. SSR can be of value in the diagnosis of autonomic nerve dysfunction in PD.     

动静脉联合介入治疗颅内静脉血栓

颅内静脉窦血栓(cerebral venous thrombosis,CVT)是缺血性脑血管病的一种少见类型,病因复杂且发病率低,治疗方法多但缺乏规范化治疗。目前微创治疗以其创伤小、见效快得到广泛开展,同样也涉及CVT的治疗。现选取2006年7月至2010年6月23例应用动静脉联合介入治疗的CVT患者,总结如下。     

帕罗西汀致焦虑样发作3例

中国人民解放军第１０２医院神经科　赵建法　于苏文报道　例１：女,２３岁。因产后无故担心,紧张,夜眠差２个月于１９９８年２月门诊。根据ＣＣＭＤⅡＲ诊断为焦虑性神经症,予服用帕罗西汀（赛乐特）２０ｍｇ／ｄ,每晚服阿普伦０４ｍｇ。服药后次日出现明显紧张、烦躁、坐立不安、浑身不适,难以忍受,来院急诊,经减量赛乐特１０ｍｇ／ｄ（早上）,佳乐定改为每晚服０８ｍｇ,次日症状明显减轻,能平静入睡,减量后第３天症状完全消失,维持治疗半年无复发。　　例２：女,５１岁。因紧张不安,头昏、头晕、夜眠差９个月于１…     

支架成形术治疗椎动脉狭窄

目的评价椎动脉狭窄支架成形术的疗效。方法采用球囊扩张支架对椎动脉狭窄段进行支架成形术,使椎动脉狭窄段恢复正常管径。结果23例病人共放置27枚支架,椎动脉狭窄率术前平均为73．2%,术后为25．7%,造影示狭窄段全部成形良好,无并发症发生。随访3～18月,患者临床症状消失18例,症状明显改善4例,症状复发1例。结论支架成形术治疗椎动脉狭窄是一种安全有效的方法。     

帕金森病交感神经皮肤反应的临床研究

Objective To assess the value of detecting sympathetic skin response (SSR) in the diagnosis of autonomic dysfunction in patients with Parkinson disease (PD). Methods SSR measurement was performed in 47 PD patients and 20 healthy control subjects and the results were compared. The SSR was also comparatively analyzed between patients with and those without autonomic dysfimction. Results Compared with the healthy controls, the PD patients showed significantly lowered mean amplitude (2.56±1.47 vs 1.87±0.26, P<0.05) and prolonged latency (1.42±0.29 vs 1.55± 0.18, P<0.05) of the SSR in the upper limbs, with also lowered mean amplitude (0.76±0.39 vs 0.49±0.21, P<0.05) and prolonged latency (2.04±0.27 vs 2.13±0.16, P<0.05) in the lower limbs. Compared with the PD patients without autonomic dysfunction, those having autonomic dysfunction showed significantly lowered mean amplitude (1.89±0.33 vs 1.75±0.21, P<0.05) and prolonged latency (1.53±0.15 vs 1.56±0.17, P<0.05) of SSR in the upper limbs and lowered mean amplitude (0.51±0.17 vs 0.46±0.20,P<0.05) and prolonged latency (2.08±0.24 vs 2.17±0.18, P<0.05) in the lower limbs. Conclusion The results of SSR measurements are consistent with the clinical manifestations of the PD patients. SSR can be of value in the diagnosis of autonomic nerve dysfunction in PD.     

脊髓痨一例报告

患者 ,男性 ,5 8岁 ,因行走不稳、双下肢乏力 2个月余 ,于1999年 10月 13日入院。 1998年 8月起 ,无明显诱因渐感左足趾发麻、低热 ,右足趾也渐感发麻 ,行走时如踩棉花样 ,乏力 ,左侧明显 ,行走不稳 ,前冲 ,不自主摔跤 ,夜间尤明显 ,外院查头颅ＣＴ、ＭＲＩ、脑血管多普勒均无异常 ,考虑“病毒感染” ,对症治疗无效 ,于某院就诊 ,诊断为“脊髓亚急性联合变性” ,予以ＶｉｔＢ12 、叶酸等药物治疗。稍好转 ,持续治疗无进展。入院前已无法单独行走 ,双手末端麻木 ,反复呃逆 ,饮水呛咳 ,双下肢阵发性抽痛 ,小便次数减少 ,每次尿量增多 ,大便无…