Bio-inspired delayed evolutionary game dynamics with?networking applications

We study in this paper some evolutionary games where competition between individuals from a large population occurs through many local interactions between randomly selected individuals. We focus on games that have the property of possessing a single interior evolutionarily stable strategy (ESS). We study in particular the effect of the time delays on the convergence of evolutionary dynamics to the ESS in an evolutionary game in which each pure strategy is associated with its own delay. In particular, we study a multiple access game as well as a Hawk and Dove game. We study the properties of the ESS in these games and also the effect of time delays on the convergence of various bio-inspired evolutionary game dynamics to the ESS.     

From contact angle titration to chemical force microscopy: a new route to assess the pH-dependent character of the stratum corneum

Despite of its complex multicomponent organization and its compact architecture, the Stratum corneum (SC) is not completely impermeable to substances directly applied on the skin surface. A huge number of works have been dedicated to the understanding of the mechanisms involved in substance permeation by exploring deeper layers than the SC itself. Surprisingly, there is a poor interest in studies relating to interactions which may occur in the near-surface region (i.e. approximately 1 nm depth) of the SC. In this work, equilibrium proton-transfer reactions have been used as probes to define in a fundamental point of view the nature of the SC interactions with its environment. Such titration curves are investigated on 'in vitro' SC (isolated SC from abdominal skin tissue) and on 'in vivo' volar forearm (a sebum poor area). The results are discussed in term of work of adhesion and surface pKa values. Because SC can 'reconstruct' under heating, influence of the temperature on titration curves is investigated and the role of the different components is discussed. Different sigmoidal transitions were observed. Two common pKa values (pKa(1) = 4 and pKa(2) = 11.5) were clearly identified in both cases and associated to an acid-base character. By playing with the temperature of 'in vitro' SC, the 'accessibility' of polar functions was increased, thus refining the results by revealing an amphoteric character with an acid-to-base transition at pH 3.5 and two acid transitions at pH = 6.5 and pH = 11.5. Adhesion forces between an Atomic Force Microscopy (AFM) tip and a single isolated corneocyte through buffered liquid media were also investigated to better understand the role of the individual corneocytes.     

Signaling game approach to improve the MAC protocol in the underwater wireless sensor networks

Underwater sensor networks (UWSNs) are instructed for critical applications like military surveillance and underwater oil spills that conducted in a very massive three‐dimensional (3‐D) space that needs many underwater nodes (UNs) to cover the target area. Those UNs are not easy to recharge and cannot exploit solar power. MAC protocols deployed for UWSN ought to consider the energy efficiency, so as, to extend the network lifetime with total connectivity and significant throughput. Terrestrial MAC protocols could not be used for UWSN due to long and unpredictable propagation delay. Consequently, the development of a new MAC protocol for the harsh environment as underwater is a challenging task. In this study, we focus on the deployment of TDMA in UWSN for this, two schemes entitled TDMA slot sharing (TSS) and free time slots reallocation (FTSR) are proposed. Received data stored in the buffer waiting for processing and forwarding might lead to an unlimited data transfer latency those results in the buffer overflow. Otherwise, free time slots appearing during the communication process resulting from dead nodes increase uselessly sleep time for the rest of the nodes. Both schemes based on signaling game are proposed to overcome those problems, TSS is used to enable the slot sharing between UNs during the communication process to reduce the buffer overflow. FTSR scheme aims to increase the throughput of UNs by allowing the reuse of free time slots. Numerical results conducted in this work show good improvement in the network performance concerning throughput.     

Prognostic factors for survival and response after high-dose therapy and autologous stem cell transplantation in systemic AL amyloidosis: a report on 21 patients

We retrospectively investigated the feasibility and the toxicity of autologous stem cell transplantation (ASCT) in 21 cases of systemic amyloidosis (AL). The conditioning regimens consisted of high-dose melphalan (HDM) alone (n = 18) or in combination with 12 Gy total body irradiation (n = 3). Toxic death rate was high: 9/21 patients (43%) died within the first month following ASCT, and 10/12 surviving patients achieved a response. With a median follow-up of 14 months, the OS and the EFS rates at 4 years were 57.1% (+/-10.8) and 29.9% (+/-14.5) respectively for the whole group. The major prognostic factor for both response and survival was the number of clinical manifestations at the time of ASCT, of the following five criteria, i.e. creatinine clearance < 30 ml/min, nephrotic syndrome with urinary protein excretion > 3000 mg/24 h, congestive heart failure, neuropathy, or hepatomegaly associated with alkaline phosphatase level > 200 IU/l. For patients presenting with two or more clinical manifestations the 4-year OS and EFS were both 11.1% compared with 91.7% and 46.3% respectively in patients with fewer than two clinical manifestations at the time of ACST. We conclude that ASCT is feasible in AL in a subset of patients with fewer than two clinical manifestations at the time of ASCT. Given the severe extra-haematological toxicity, ASCT should not be considered in other cases.     

Dynamic robust power allocation games under channel uncertainty and time delays

In this paper, we study dynamic robust power allocation strategies under the imperfectness of the channel state information at the transmitters. Considering unknown payoff functions at the transmitters, we propose an heterogeneous Delayed COmbined fully DIstributed Payoff and Strategy Reinforcement Learning (Delayed-CODIPAS-RL) in which each transmitter learns its payoff function as well as its associated optimal strategies in the long-term. We show that equilibrium power allocations can be obtained using the multiplicative weighted imitative CODIPAS-RLs and Bush-Mosteller based CODIPAS-RL. We also show almost sure convergence to the set of global optima for specific scenarios.     

Ultrasonic cavitation test applied to thin metallic films for assessing their adhesion with mercaptosilanes and surface roughness

Evaluating the adhesion of micrometer or nanometer thick coatings is a challenging question which concerns many application fields. This is especially true for thin films deposited on a substrate of elastic modulus higher than that of the film, or for granular coatings, that do not allow the use of common adhesion tests. Usually, applied to characterize the wear resistance of bulk materials or thick coatings, the ultrasonic cavitation test is applied here to evaluate the adhesion strength of gold and copper thin films (~200 nm) that are evaporated on a silicon substrate. The test is shown to be sensitive enough to discriminate the influence of the surface chemistry on the adhesion strength of gold and copper films. Particularly, the role of (3-mercaptopropyl)triethoxysilane as an effective adhesion promotor is demonstrated. Furthermore, the role of surface roughness of the substrate is characterized and discussed in order to get further insights on the way this parameter interferes with the ultrasonic test and determines the adhesive strength of the coating. An estimate of the adhesive strength is given on the basis of the coating delamination kinetics.