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排序方式: 共有797条查询结果,搜索用时 62 毫秒
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Christopher M. Gourlay Arne K. Dahle Hans I. Laukli 《Metallurgical and Materials Transactions A》2004,35(9):2881-2891
Banded defects are often found in high-pressure die castings. These bands can contain segregation, porosity, and/or tears,
and changing casting conditions and alloy are known to change the position and make-up of the bands. Due to the complex, dynamic
nature of the high-pressure die-casting (HPDC) process, it is very difficult to study the effect of individual parameters
on band formation. In the work presented here, bands of segregation similar to those found in cold-chamber HPDC aluminum alloys
were found in laboratory gravity die castings. Samples were cast with a range of fraction solids from 0 to 0.3 and the effect
of die temperature and external solid fraction on segregation bands was investigated. The results are considered with reference
to the rheological properties of the filling semisolid metal and a formation mechanism for bands is proposed by considering
flow past a solidifying immobile wall layer. 相似文献
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HJ Lee HK Ha MH Kim YK Jeong PN Kim MG Lee JS Kim DJ Suh SG Lee YI Min YH Auh 《Canadian Metallurgical Quarterly》1997,169(2):517-520
OBJECTIVE: The purpose of this study was to evaluate ERCP and CT findings of ectopic drainage of the common bile duct into the duodenal bulb. CONCLUSION: Although rare, the diagnosis of ectopic drainage of the common bile duct into the duodenal bulb is important to prevent inadvertent damage during biliary tract or gastric surgery and to clarify the cause of chronic peptic ulcers. 相似文献
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A chimeric dopamine transporter (DAT) cDNA encoding mutant human DAT (hDAT) protein in which the intracellular carboxyl-terminal tail is replaced by that of the bovine dopamine transporter (bDAT) was constructed. The chimeric hDAT cDNA was expressed in COS-7 cells, and [3H]dopamine and [3H]MPP+ uptake and [3H]CFT binding capacities were assessed. Substrate transport and ligand binding of bDAT were reduced by 32-43% as a result of substitution of the carboxyl tail in hDAT, suggesting that the functional characteristics of bDAT arise from differences in the carboxyl tail between human and bovine DAT. Thus, it appears that the sequences encoded within the carboxyl terminal of DAT would be one of the important determinants for its functions. 相似文献
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C. M. Dinnis A. K. Dahle J. A. Taylor M. O. Otte 《Metallurgical and Materials Transactions A》2004,35(11):3531-3541
Strontium modification is known to alter the amount, characteristics, and distribution of porosity in Al-Si castings. Although
many theories have been proposed to account for these effects, most can be considered inadequate because of their failure
to resolve contradictions and discrepancies in the literature. In an attempt to critically appraise some of these theories,
the amount, distribution, and morphology of porosity were examined in sand-cast plates of Sr-free and Sr-containing pure Al,
Al-1 wt pct Si, and Al-9 wt pct Si alloys. Statistical significance testing was used to verify apparent trends in the porosity
data. No apparent differences in the amount, distribution, and morphology of porosity were observed between Sr-free and Sr-containing
alloys with no or very small eutectic volume fractions. However, Sr modification significantly changed the amount, distribution,
and morphology of porosity in alloys with a significant volume fraction of eutectic. The addition of Sr reduced porosity in
the hot spot region of the casting, and the pores became well dispersed and rounded. This result can be explained by considering
the combined effect of the casting design and the differences in the pattern of eutectic solidification between unmodified
and Sr-modified alloys. 相似文献
9.
The antinociceptive effects of morphine (5 micrograms) microinjected into the ventrolateral periaqueductal gray were determined using both the tail flick and the foot withdrawal responses to noxious radiant heating in lightly anesthetized rats. Intrathecal injection of appropriate antagonists was used to determine whether the antinociceptive effects of morphine were mediated by alpha 2-noradrenergic, serotonergic, opioid, or cholinergic muscarinic receptors. The increase in the foot withdrawal response latency produced by microinjection of morphine in the ventrolateral periaqueductal gray was reversed by intrathecal injection of the cholinergic muscarinic receptor antagonist atropine, but was not affected by the alpha 2-adrenoceptor antagonist yohimbine, the serotonergic receptor antagonist methysergide, or the opioid receptor antagonist naloxone. In contrast, the increase in the tail flick response latency produced by morphine was reduced by either yohimbine, methysergide or atropine. These results indicate that microinjection of morphine in the ventrolateral periaqueductal gray inhibits nociceptive responses to noxious heating of the tail by activating descending neuronal systems that are different from those that inhibits the nociceptive responses to noxious heating of the feet. More specifically, serotonergic, muscarinic cholinergic and alpha 2-noradrenergic receptors appear to mediate the antinociception produced by morphine using the tail flick test. In contrast, muscarinic cholinergic, but not monoamine receptors appear to mediate the antinociceptive effects of morphine using the foot withdrawal response. 相似文献
10.
SB Levery MS Toledo E Suzuki ME Salyan S Hakomori AH Straus HK Takahashi 《Canadian Metallurgical Quarterly》1996,222(2):639-645
An acidic glycolipid (Band 1), purified from P. brasiliensis by a combination of ion exchange chromatography, HPLC, and HPTLC, was found to be reactive with sera of all patients with paracoccidioidomycosis (PCM). Monosaccharide analysis of Band 1 yielded mannose and galactose in a 2:1 ratio, while mild acid hydrolysis and mild periodate oxidation/NaB3H4 reduction indicated the presence of a terminal galactofuranose. Preliminary analysis of 1H-NMR and MS data suggests that the structure of the glycan is Galf beta 1-->6(Manp alpha 1-->3)Manp beta 1-->2Ins (Ins = myo-inositol). Removal of the galacto-furanose decreased by 60-80% the reactivity of sera from PCM patients with Band 1, suggesting that this residue is immunodominant. With the presumed absence of galactofuranose in mammalian hosts, compounds containing this residue may be useful targets for therapy of several parasitic and fungal diseases. 相似文献