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Andreia Coroas José G G de Oliveira Susana Sampaio Cátia Borges Isabel Tavares Manuel Pestana Maria D V de Almeida 《Journal of renal nutrition》2004,14(3):157-163
OBJECTIVE: Kidney transplantation restores renal filtration, although it does not achieve the function of 2 native kidneys, and with time it may involute back to chronic renal failure. We hypothesized that bioelectrical impedance analysis (BIA) might highlight differences for body compartments among kidney transplants (Tx) with different filtration rates. METHODS: Thirty transplantation patients (19 male, 11 female) were studied at 62.4+/-26.6 months postsurgery and were divided into 3 groups: good creatinine clearance (crCl, mL/min/1.73 m2; >65.0), borderline (35.0相似文献
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Ana Teresa Timóteo Andreia Mamede Maria de Lurdes Ferreira José Serra José Alberto Oliveira Rui Cruz Ferreira Jorge Quininha 《Revista portuguesa de cardiologia》2007,26(2):135-143
BACKGROUND: Nitrate therapy can induce ischemic preconditioning with a consequent increase in tolerance to ischemia. In the context of acute coronary syndromes (ACS), nitrates may result in a different presentation. with greater protection. OBJECTIVES: To investigate in a population of patients with ACS whether previous chronic use of nitrates results in a different presentation of ACS. METHODS: We studied 287 patients (65 +/- 13 years, 66% male) admitted to our department in the first six months of 2005 with ACS (with and without ST-segment elevation). Of these, 8% were under nitrate therapy at the time of admission. In this group, 27% presented ACS without ST-segment elevation, while in the group without nitrates this value was 58% (p = 0.005). By univariate analysis, the use of nitrates was a predictor of the preferential occurrence of non-ST-segment elevation ACS (OR 0.27, 95% CI 0.10-0.71). After correction for the potential influence of variables (age, gender, previous revascularization and smoking) by multivariate logistic regression, nitrate therapy remained a borderline predictor of clinical presentation as non-ST-segment elevation ACS (OR 0.37, 95% CI 0.13-1.04, p = 0.059). CONCLUSIONS: Previous use of nitrates was associated with a tendency to present as non-ST-segment elevation ACS. This finding may be explained by the hypothesis that nitrates induce pharmacological preconditioning, reducing the transmural extent of myocardial infarction. 相似文献
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Rocha AM Rocha GA Santos A de Oliveira CA Queiroz DM 《Journal of clinical microbiology》2003,41(1):447-448
We validated a commercial enzyme-linked immunosorbent assay for the detection of anti-CagA antibodies in Brazilian patients with Helicobacter pylori infection. The test presented high sensitivity (97.4%) and specificity (88.9%) when employed in patients without gastric carcinoma. However, in gastric carcinoma patients, the test was neither sensitive nor specific enough to detect cagA-positive H. pylori infection. 相似文献
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Anand Shah Danny O Jacobs Henrique Martins Matthew Harker Andreia Menezes Mariana McCready Ricardo Pietrobon 《BMC medical informatics and decision making》2006,6(1):34
Background
The Internet has been increasingly utilized in biomedical research. From online searching for literature to data sharing, the Internet has emerged as a primary means of research for many physicians and scientists. As a result, Web-based surveys have been employed as an alternative to traditional, paper-based surveys. We describe DADOS-Survey, an open-source Web-survey application developed at our institution that, to the best of our knowledge, is the first to be compliant with the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). DADOS-Survey was designed with usability as a priority, allowing investigators to design and execute their own studies with minimal technical difficulties in doing so. 相似文献6.
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Kuhn Josepha van den Berg Pieter Mamede Silvia Zwaan Laura Bindels Patrick van Gog Tamara 《Advances in health sciences education : theory and practice》2022,27(1):189-200
Advances in Health Sciences Education - When physicians do not estimate their diagnostic accuracy correctly, i.e. show inaccurate diagnostic calibration, diagnostic errors or overtesting can occur.... 相似文献
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Rosby Lucy V. Schmidt Henk G. Tan Gerald J. S. Low-Beer Naomi Mamede Silvia Zwaan Laura Rotgans Jerome I. 《Advances in health sciences education : theory and practice》2021,26(3):1059-1074
Advances in Health Sciences Education - It was recently shown that novice medical students could be trained to demonstrate the speed-to-diagnosis and diagnostic accuracy typical of System-1-type... 相似文献
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Lucy Victoria Rosby Jerome I. Rotgans Gerald Tan Naomi Low-Beer Silvia Mamede Laura Zwaan 《Medical teacher》2018,40(10):1030-1035
AbstractPurpose: Diagnostic reasoning literature debates the significance of “dual-process theory” and the importance of its constituent types of thinking: System-1and System-2. This experimental study aimed to determine whether novice medical students could be trained to utilize System-1 thinking when making diagnoses based on chest X-rays.Method: Second-year medical students were recruited and presented with a series of eight online chest X-rays cases. Participants were shown half of the cases repeatedly during a training phase and the other half only twice. During the final test phase, they were shown all eight cases, providing a diagnosis as a free text answer. Dependent variables were diagnostic accuracy and response time.Results: Thirty-two students participated. During the test phase, students responses were significantly more accurate and faster for cases which had been seen repeatedly during the training phase (mean score?=?3.56/4, mean time?=?2.34?s) compared with cases which had been seen only twice (mean score?=?1.59/4, mean time?=?7.50?s).Conclusion: This study demonstrates that it is possible to induce in novice students the speed-to-diagnosis and diagnostic accuracy typical of System-1-type reasoning. The full experimental design and the chest X-rays used may provide new opportunities to explore some of the issues surrounding dual-process theory. 相似文献