Exploiting knowledge ontology and software agents for PPI network analysis

One major goal of functional genomics has been to identify and analyze molecular interactions in a cellular context to better understand the underlying design principles and mechanisms. To investigate into a PPI network from both topological and functional points of view, this work proposes a methodology that exploits ontology-based biological knowledge for network analysis. To speed up the procedure, an agent-based framework is also presented for supporting distributed computing. The preliminary results show that through the knowledge obtained from gene ontology, our work in analyzing building blocks of PPI networks can give a higher resolution than that of previous ones. Also our agent-based framework can successfully speed up the task of network analysis in an adaptive manner.     

Performance Bounds for Convolutional Codes with Digital Viterbi Decoders in Gaussian Noise

With digital implementations of the Viterbi decoding algorithm for convolutional codes, soft quantization is preferred over hard quantization because it generally yields superior performance. Since the decoder needs to know the signal energy and channel noise variance with soft quantization, inaccurate information can result in a mismatch between the channel and decoder. Bounds which are tight for high signal-to-noise ratios are obtained on the bit error probability using the generating function approach. Automatic gain control level inaccuracies, imperfect carrier phase, symbol timing synchronization error, and path metric digitization are discussed in the context of a mismatch between the channel and decoder.     

Multimicroprocessor-based robust control of an AC induction servomotor

A multiloop feedback control system supplemented by a complementary controller is used to improve the drive performance of an AC induction servo motor and reduce sensitivity to parameter variations, nonlinear effects, and load disturbances. Based on the principle of field-oriented vector control, a software-based current-decoupled controller has been proposed. A simplified model of the current-decoupled induction motor has been used for the design and simulation of the proposed robust controller. Experimental results based on multimicroprocessor implementation are presented to illustrate improved response and reduced sensitivity     

Desktop rapid prototyping system with supervisory control andmonitoring through Internet

Rapid prototyping (RP) can enhance design and manufacturing productivity by taking advantage of the Internet. Via the Internet, most small and medium size companies should be able to share the access of the RP machine remotely without owning the expensive machines. This study combines RP preprocessing, RP machine, and the Internet into a telecontrolled manufacturing system. Also presented is the software and hardware for a new LCD-based photosensitive resin RP machine that uses only visible light. This visible light can expose and solidify an entire layer at once, layer-by-layer, until the whole part is finished. The user sends a three-dimensional (3-D) CAD model (STL file) via the Internet to a telecontrol server, which transforms the CAD model into a RP machine LCD photomask display. The user can then direct the RP machine to build the RP part while watching a live image of the part via the World Wide Web. An online visual system allows inspection of the RP part quality during manufacturing. Part building is monitored by a pattern matching algorithm which compares a grabbed image with the photomask. If the grabbed image is not adequately similar to the photomask, the program stops manufacture and notifies the user. The experimental results show that RP using the Internet is promised, but the surface roughness should be further improved     

The performance of message-passing using restricted virtual memory remapping

DASH is a distributed operating system kernel. Message-passing (MP) is used for local communication, and the MP system uses virtual memory ( VM) remapping instead of software memory copying for moving large amounts of data between virtual address spaces. Remapping eliminates a potential communication bottleneck and may increase the feasibility of moving services such as file services to the user level. Previous systems that have used VM remapping for message transfer, however, have suffered from high per-operation delay, limiting the use of the technique. The DASH design reduces this delay by restricting the generality of remapping: a fixed part of every space is reserved for remapping, and a page's virtual address does not change when it is moved between spaces. We measured the performance of the DASH kernel for Sun 3/50 workstations, on which memory can be copied at 3·9 MB/s. Using remapping, DASH can move large messages between user spaces at a rate of 39 MB/s if they are not referenced and 24·8 MB/s if each page is referenced. Furthermore, the per-operation delay is low, so VM remapping is beneficial even for messages containing only one page. To further understand the performance of the DASH MP system, we broke an MP operation into short code segments and timed them with microsecond precision. The results show the relative costs of data movement and the other components of MP operations, and allow us to evaluate several specific design decisions.     

Removal of 2,4,6-trichlorophenol from a solution by humic acids repeatedly extracted from a peat soil

Humic acid (HA) is one of the major components of soil organic matter. It strongly affects the sorption behavior of organic and inorganic contaminants in soils. To obtain a better understanding of the interactions of contaminants with HA, a repeated extraction technique has been applied to a peat soil to obtain HA fractions with varying aliphaticity and aromaticity, which were subsequently correlated to the sorption properties of 2,4,6-trichlorophenol (TCP). HA fractions were extracted repeatedly using an alkaline solution and each HA fraction was separated into two portions with an air-drying or re-suspending (denoted as RSHAs) process. Solid-state (13)C NMR and elemental analysis demonstrated that the aromaticity and polarity of HAs decreased with extractions. Kinetic results indicated that air-dried HAs exhibited two-step first order sorption behavior with a rapid stage followed by a slower stage. The slower sorption is attributed to the diffusion of 2,4,6-TCP in the condensed aromatic domains of HAs. Conversely, sorption of 2,4,6-TCP on RSHAs was extremely rapid and could not be fitted with any kinetic model. For air-dried HAs the sorption capacity (K(oc)) was weakly correlated with the chemical compositions of HAs. However, a positive trend between K(oc) and aromaticity was observed for RSHAs. Compared with the results of air-dried HAs with their counterparts of RSHAs, it is therefore concluded that air-drying may alter the structure of HAs through artificially creating a more condensed domain in HAs. The structural alternation may result in an incorrect interpretation of the relationship between sorption capacity and chemical composition of HAs and a misjudgment of the transport behavior of 2,4,6-TCP in soils and sediments.     

The removal and recovery of Cr(VI) by Li/Al layered double hydroxide (LDH)

Hexavalent Cr has been identified as one of the toxic metals commonly present in industrial effluents. Among the treatment techniques developed for removing Cr(VI) from waste waters, sorption is most commonly applied, due to its simplicity and efficiency. However, few adsorbents can be recycled and reused cost-effectively. In this study, the removal and recovery of Cr(VI) from water using Li/Al LDH was investigated. The removal of Cr(VI) by Li/Al LDH was evaluated in a batch mode. The results demonstrated that Cr(VI) adsorption onto Li/Al LDH occurs by replacing the Cl(-) that originally exists in the interlayer of the adsorbent. The degree of Cr(VI) adsorption observed for Li/Al LDH was relatively high and the process occurred rapidly; however, a portion of adsorbed Cr(VI) was gradually desorbed, due to the Li de-intercalation of Li/Al LDH. Lithium de-intercalation from Li/Al LDH with interlayer Cl(-) and interlayer Cr(VI) follows the first order kinetics and has the activation energies of 76.6 and 41.5 kJ mol(-1), respectively. The properties of thermal unstability and the high adsorption capacity of Li/Al LDH may lead to the development of an innovative technique for the removal of Cr(VI) from Cr(VI)-containing wastewater. That is, Li/Al LDH may be used as an effective adsorbent for the adsorption of Cr(VI) in an ambient environment. Following the adsorptive process, the adsorbed Cr(VI) may be released, using heated water to treat the Cr(VI)-containing Li/Al LDH particles. Through this hydrothermal treatment of the used adsorbent, Cr(VI) can be recovered and the solid product (gibbsite) can be recycled for further use.     

Strain energy density – a molecular appraisal

Abstract

The interaction potential between two clusters simulating the crack tip on the lattice level is derived in this work. Employing molecules as the building blocks and the Lennard‐Jones potential as the Green's function, the close‐form solution shows that the 1/r‐type of singularity is an intrinsic behavior of the energy field when mutual attraction dominates the lattice interactions. This behavior is now proven, explicitly, to be independent of the constitutive equation of the material.