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Multi-element ultrasound phased array applicator for the ablation of deep-seated tissue 总被引:1,自引:0,他引:1
High-intensity focused ultrasound (HIFU) has attracted increasing interests as a promising noninvasive modality for the treatment
of deep tumors in the thoracic and abdominal cavity. A 90-element HIFU spherical phased array applicator operated at 1MHz
has been developed for deep tissue ablation. The spherical array with a 5 cm wide central hole has a 21 cm diameter and an
18 cm radius of curvature. Annular element distribution with unequal element spacing is used to reduce the number of elements.
The array is constructed with piezoelectric lead zirconate titanate (PZT-8) circular elements that are 1.4 cm in diameter
and have a wall with thickness of 0.2 cm. The array offers an effective ablating depth of at least 8 cm in the tissue for
both simulations and ex vivo experiments. The simulations demonstrate that the developed array can steer the focus with good
quality of intensity distributions up to 6mm off center over ranges from 17 to 21 cm when the water depth is set at 11 cm.
We also present the beam focusing capability in deep tissue through a series of ex vivo experiments by measuring discoloration
areas after sonications. These results indicate that the developed array is ideal for the ablation of deep-seated tissue. 相似文献
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