全文获取类型
收费全文 | 1047篇 |
免费 | 86篇 |
国内免费 | 21篇 |
学科分类
医药卫生 | 1154篇 |
出版年
2021年 | 19篇 |
2020年 | 6篇 |
2019年 | 6篇 |
2018年 | 8篇 |
2017年 | 13篇 |
2016年 | 15篇 |
2015年 | 16篇 |
2014年 | 25篇 |
2013年 | 34篇 |
2012年 | 37篇 |
2011年 | 29篇 |
2010年 | 40篇 |
2009年 | 42篇 |
2008年 | 19篇 |
2007年 | 35篇 |
2006年 | 31篇 |
2005年 | 26篇 |
2004年 | 28篇 |
2003年 | 13篇 |
2002年 | 23篇 |
2001年 | 19篇 |
2000年 | 14篇 |
1999年 | 26篇 |
1998年 | 38篇 |
1997年 | 40篇 |
1996年 | 32篇 |
1995年 | 31篇 |
1994年 | 17篇 |
1993年 | 21篇 |
1992年 | 13篇 |
1991年 | 14篇 |
1990年 | 22篇 |
1989年 | 24篇 |
1988年 | 28篇 |
1987年 | 30篇 |
1986年 | 25篇 |
1985年 | 31篇 |
1984年 | 18篇 |
1983年 | 20篇 |
1982年 | 17篇 |
1981年 | 15篇 |
1980年 | 22篇 |
1979年 | 8篇 |
1978年 | 13篇 |
1977年 | 23篇 |
1976年 | 15篇 |
1975年 | 13篇 |
1974年 | 8篇 |
1972年 | 10篇 |
1970年 | 10篇 |
排序方式: 共有1154条查询结果,搜索用时 46 毫秒
1.
2.
3.
4.
5.
Induction of MHC class II expression in recipient tissues caused by allograft rejection 总被引:2,自引:0,他引:2
MHC class II antigens (DR) are not commonly expressed on parenchymal cells of kidney and liver except when they are allografts undergoing rejection. The objective of this study was to determine whether allograft rejection can also induce DR upregulation in parenchymal cells of autologous recipient organs. Dogs had unilateral renal autografts to facilitate kidney sampling. All kidneys were tubular cell DR-negative. After 8-14 days each dog received a tubular cell DR-negative allograft. Tubular cell DR became positive in both allograft and autograft simultaneously, its onset and intensity correlating with blast cell infiltration and rejection in the allograft. Blast cells were first detected in the autograft after allograft nephrectomy, and then disappeared as autograft tubular cell DR diminished over the next 6-8 days. This was reproduced on repeat allografting. In 2 untreated dogs hepatocytes became positive on day 4, with no hepatic blast infiltrate. Four other dogs received cyclosporine immunosuppression. Allograft and autograft tubular cell DR, and hepatocyte DR, increased in all dogs, but were delayed while on CsA until onset of rejection despite transient earlier allograft blast infiltration. Downregulation in autograft and liver occurred together after allograft nephrectomy. An interferon-like substance appeared in plasma after allografting in association with the DR changes in native kidney and liver. Renal allorejection therefore induces upregulation of parenchymal DR expression in autologous liver and kidney of the recipient. It is probably mediated by an interferon-like substance derived from cells infiltrating the allograft. The effect is modified by CsA. 相似文献
6.
Kinnison ML; Perler BA; Kaufman SL; Mitchell SE; Kadir S; Williams GM; White RI Jr 《Radiology》1986,160(3):727-730
In situ saphenous vein grafts are being used with increasing frequency for bypass procedures involving the femoral and popliteal arteries. Complications of these procedures include anastomotic stenoses and persistent arteriovenous fistulae that may result in failure of the graft. Balloon angioplasty and embolotherapy with detachable balloons were employed successfully in three or four recent cases of patients with complications from in situ grafts. Tailored angiography is essential for evaluating in situ grafts, and interventional techniques are extremely useful for managing complications. 相似文献
7.
8.
Polycystic kidney disease is an autosomal dominant disease that may be associated with cystic disease of the liver. In women, the cysts may develop early and be more troublesome than in men. Cystadenocarcinoma of the pancreas is uncommon, comprising 1% of primary pancreatic malignancies. This case report is the first to describe a familial association between polycystic kidney disease and cystadenocarcinoma of the pancreas and liver in the English medical literature. A patient with autosomal dominant polycystic kidney disease (ADPKD) and multiple hepatic cysts developed cystadenocarcinoma of the pancreas with multiple malignant liver cysts. The patient's mother, sister, and niece had ADPKD, and the patient's sister also died of pancreatic cystadenocarcinoma. We believe that the development of these two disease entities in which the primary pathology is cyst formation has a genetic association. (Gastroenterology 1997 Jun;112(6):2104-7) 相似文献
9.
Pheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintigraphy 总被引:6,自引:0,他引:6
To ascertain the magnetic resonance (MR) imaging characteristics of pheochromocytomas and paragangliomas and to compare MR with computed tomography (CT) and iodine-131 metaiodobenzylguanidine (I-131 MIBG), 19 patients (18 with pheochromocytomas, one with a paraganglioma) were studied. The 18 patients with pheochromocytomas had had positive findings with I-131 MIBG scintigraphy. Abdominal pheochromocytomas were generally hypointense compared with normal liver on T1-weighted MR images and extremely hyperintense on T2-weighted MR images. MR imaging was preferable to CT in the evaluation of primary pheochromocytomas due to superior tissue characterization, particularly in the patient with hypertension and borderline catecholamine levels. For patients with recurrent or metastatic disease, the data suggest that I-131 MIBG scintigraphy is the examination of choice. 相似文献
10.
Evaluation of a new enzyme-linked immunosorbent assay test for rotavirus antigen in faeces 总被引:6,自引:0,他引:6 下载免费PDF全文
A new commercial test for the diagnosis of rotavirus gastroenteritis was assessed. With some modifications it compared favourably with electron microscopy and immunofluorescence. 相似文献