Therapeutic management in trochanteric fractures

The authors present the management of trochanteric fractures based on 343 fractures treated in Department of Orthopaedics and Trauma in Clinical Hospital of Emergencies of Ia?i for 5 years. The non-operative treatment was used in 17.2% of cases and the conservative methods were plaster immobilization, continuous traction and early mobilization. The surgical treatment was used in 82.8% of cases. The reduction of the fractures was usually possible using closed methods. For fixation, the authors used four types of implants: the 135 degrees blade-plate in 9.2% of cases, the condylar blade plate in 44.7%, Ender nails in 45.4% and DHS in 0.6% of cases. The choice of one of this methods depends on the type of fracture, age of the patient and on his biological status.     

Perfect Laplacians for Polygon Meshes

A discrete Laplace‐Beltrami operator is called perfect if it possesses all the important properties of its smooth counterpart. It is known which triangle meshes admit perfect Laplace operators and how to fix any other mesh by changing the combinatorics. We extend the characterization of meshes that admit perfect Laplacians to general polygon meshes. More importantly, we provide an algorithm that computes a perfect Laplace operator for any polygon mesh without changing the combinatorics, although, possibly changing the embedding. We evaluate this algorithm and demonstrate it at applications.     

Enhancing self-scheduling algorithms via synchronization and weighting

Existing dynamic self-scheduling algorithms, used to schedule independent tasks on heterogeneous clusters, cannot handle tasks with dependencies because they lack the support for internode communication. To compensate for this deficiency we introduce a synchronization mechanism that provides inter-processor communication, thus, enabling self-scheduling algorithms to handle efficiently nested loops with dependencies. We also present a weighting mechanism that significantly improves the performance of dynamic self-scheduling algorithms. These algorithms divide the total number of tasks into chunks and assign them to processors. The weighting mechanism adapts the chunk sizes to the computing power and current run-queue state of the processors. The synchronization and weighting mechanisms are orthogonal, in the sense that they can simultaneously be applied to loops with dependencies. Thus, they broaden the application spectrum of dynamic self-scheduling algorithms and improve their performance. Extensive testing confirms the efficiency of the synchronization and weighting mechanisms and the significant improvement of the synchronized–weighted versions of the algorithms over the synchronized-only versions.     

Representing Animations by Principal Components

In this paper, we present a representation for three-dimensional geometric animation sequences. Different from standard key-frame techniques, this approach is based on the determination of principal animation components and decouples the animation from the underlying geometry. The new representation supports progressive animation compression with spatial, as well as temporal, level-of-detail and high compression ratios. The distinction of animation and geometry allows for mapping animations onto other objects.     

Synthesis of nanozirconooligocarbosilanes

We describe the first chlorine-free synthesis of nanozirconooligocarbosilanes through thermal cocondensation of low-molecular oligocarbosilanes and zirconium tetrakis(diethylamide). The starting reagents, reaction intermediates, and final products have been characterized by ¹H, ¹³C, and ²⁹Si nuclear magnetic resonance, UV and IR spectroscopy, gel-permeation chromatography, thermogravimetry, transmission electron microscopy (TEM), and elemental analysis. The synthesized nanozirconooligocarbosilanes have been used to fabricate ceramic fibers and matrices through thermal and chemical processing. TEM results demonstrate that the particles of zirconium and products of its reactions with silicon, carbon, and nitrogen range in size from 10 to 20 nm in the oligomers and from 20 to 30 nm in the ceramics.     

Betulinic Acid in Complex with a Gamma-Cyclodextrin Derivative Decreases Proliferation and in Vivo Tumor Development of Non-Metastatic and Metastatic B164A5 Cells

Betulinic acid, a very promising anti-melanoma agent, has very low water solubility that causes low bioavailability. To overcome this inconvenience, a highly water-soluble cyclodextrin was used (octakis-[6-deoxy-6-(2-sulfanyl ethanesulfonic acid)]-γ-cyclodextrin). The complex was physico-chemically analyzed using differential scanning calorimetry (DSC), X-ray and scanning electron microscopy (SEM) methods and then in vitro tested for its antiproliferative activity by the MTT assay and by cell cycle analysis. Finally, the complex was tested in vivo using an animal model of murine melanoma developed in C57BL/6J mice, where it caused a reduction in tumor volume and weight. The study revealed the beneficial influence of betulinic acid inclusion into the cyclodextrin in terms of antiproliferative activity and in vivo tumor development.