腹腔镜胆囊切除兼行其他手术28例经验

目的探讨腹腔镜联合手术的适应证和优越性。方法回顾性分析28例腹腔镜联合手术的临床资料。结果28例腹腔镜联合手术均获得成功。手术时间65~132min,平均手术时间76min,术后3~7d出院。无并发症。结论腹腔镜联合手术可安全、有效地治疗多种腹部疾病,显著减少病人的痛苦和费用,体现了微创技术的优越性,值得推广。     

神经生长因子基因转染联合强化铁营养防治豚鼠爆震性聋的实验研究

Objective To study the protective effects of adenovirus-mediated human beta-nerve growth factor gene (hNGFβ) transfer combined with iron fortified nutrition on blast hearing damage in guinea pigs. Methods Deafness was induced by blast (172dB SPL) in 35 healthy guinea pigs. Seven days after noise exposure, 10 guinea pigs were inoculated with adenovirus-mediated hNGFβ (Ad-hNGFβ) into the perilymphatic space (the gene group), another 10 guinea pigs were given hNGFβ combined with iron fortified nutritional diet (the combination group), still another 10 guinea pigs were inoculated with artificial perilymphatic fluid (APF), and 5 guinea pigs served as control, given neither medicine nor noise exposure. Auditory brainstem response (ABR) threshold shifts were monitored in the guinea pigs before blast exposure and after gene transfer. Changes in cochlear morphology were examined with immunohistochemical and HE staining. Results One week after successful inoculation of hNGFβ, it was noted that Ad-hNGFβ protein was expressed in each turn of the cochlea, and its intensity was almost equal. After gene transfer in the combination group and the gene group, ABR threshold shifts at week 1 and 4 were significantly smaller than those of the APF group. HE staining showed that the number of the spiral ganglion cells in the combination group and the Ad-hNGFβ group was significantly higher than that of the control group after 4 weeks (P<0.01). Conclusions Ad-hNGFβ combined with iron fortified nutritional diet was effective in the prevention and treatment of blast hearing damage of cochlear hair cells.     

89锶治疗骨质疏松性骨折的临床应用

笔者应用^89锶治疗脊椎骨质疏松性骨折引起顽固性疼痛，获得良好疗效，现报道如下。     

卫生类高职学校教育资源配置的作为取向

卫生类高职学校在教育资源的配置上发挥自身的能动作用，是市场机制调节的必然结果。在资源有限的情况下，既市场因素，又不能忽略高职教育培养人才的特殊性，把握其为社会服务的根本宗旨，处理好经济效益与社会效益的相互关系。     

豚鼠实验性Hanta病毒性迷路炎

内耳病毒感染可伴发耳聋。虽曾建立内耳病毒感染的动物模型,但病毒感染内耳的途径还不清楚。作者对18只雄豚鼠经右圆窗接种0.002ml Hanta病毒液入耳蜗,感染后4、6、8、10、12、16天各处死3只;2只雄豚鼠同样方法接种无病毒的培养液,作为对照;另18只雄豚鼠经腹腔内接种此病毒液1ml,其中6只于接种前3天给予环磷酰胺(CY,250mg/kg),6只接种前1天和接种后5天给予环孢霉素A     

贯彻"三个代表"思想创建一流总医院

本文阐述了以“三个代表”思想为指导，从科技强院，文化兴院和质量建院三个方面加强全面建设的经验，为全面提高军队医院建设提供参考。     

监护病房耐药菌临床分析

目的：研究加强监护病房(ICU)的耐药菌情况。方法：收集ICU 182例病人临床分离的耐药菌进行药物敏感试验。结果：共分离到748菌株，包括G杆菌386株(51．6％)，G球菌274株(36．6％)，真菌88株(11．6％)，致病菌分离95．5％来自痰培养。MBSA为最常见耐药菌，占总耐药菌的32．5％，未发现耐万古霉素的MRSA；铜绿假单胞杆菌居第2位，占总耐药菌的14．7％，亚安培南大多耐药，体外药敏试验最敏感为妥布霉素，其次为头孢哌酮／舒巴坦；鲍曼氏不动杆菌第3位，最有效为亚安培南；白色念珠菌第4位，尚未发现耐氟康唑菌株；大肠埃希菌、肺炎克雷伯杆菌仅居第6、9位，对亚安培南均敏感。结论：ICU中的耐药菌情况相似于2001年全国13家大医院的感染率，应采取必要的措施以控制和预防耐药菌的发生。     

我院门诊药物咨询分析

目的 对临床用药咨询进行分析，了解临床需要，提高临床药学服务质量。方法 收集整理400例临床药物咨询资料，对用药咨询的内容进行回顾性分析。结果 咨询中以用法用量最多（20．75％），同类药物比较居第二位（14.00％），并且归纳了门诊用药十大误区与结果。结论药物咨询可提高病人的用药依从性，确保其合理用药。     

人巨细胞病毒感染与上颌窦鳞癌

人类巨细胞病毒 (Ｈｕｍａｎｃｙｔｏｍｅｇａｌｏｖｉｒｕｓ ,ＨＣＭＶ )与人类肿瘤的关系已成为肿瘤病毒学中一个重要的研究领域。大量的分子生物学和流行病学研究结果表明 ,ＨＣＭＶ与生殖道肿瘤及口腔肿瘤关系密切[1,2 ] 。有关人乳头状瘤病毒 (Ｈｕｍａｎｐａｐｉｌｌｏｍ     

以项目为契机抓关键环节促进住院分娩

蒿县河村乡位于嵩县西南部的丘陵地带．总人口27806人．最近的村距离乡卫生院0．5km．最远的村距卫生院30km。长期以来由于当地经济贫困、交通不便．乡卫生院工作人员技术水平低、医疗设备简陋．农民健康知识缺乏．使乡卫生院妇幼保健服务提供能力和农民利用服务能力低下。2000年卫生院门诊就诊15325人次．妇产科门诊352人次．住院分娩产妇51例．全乡孕产妇住院分娩率为16．06％。