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In this paper, a modified particle swarm optimisation algorithm is proposed for protein sequence motif discovery. Protein sequences are represented as a chain of symbols and a protein sequence motif is a short sequence that exists in most of the protein sequence families. Protein sequence symbols are converted into numbers using a one to one amino acid translation table. The simulation uses EGF protein and C2H2 Zinc Finger protein families obtained from the PROSITE database. Simulation results show that the modified particle swarm optimisation algorithm is effective in obtaining global optimum sequence patterns, achieving 96.9 and 99.5 classification accuracy respectively in EGF and C2H2 Zinc Finger protein families. A better true positive hit result is achieved when compared to the motifs published in PROSITE database.  相似文献   
多序列比对问题的粒子群优化算法求解   总被引:2,自引:0,他引:2  
文章提出了一新的算法,利用粒子群优化算法求解多序列比对的问题,这是粒子群优化算法在生物信息学方面的一个新的应用。文章从粒子群算法的原理和多序列比对问题模型入手,来提出怎样改造粒子群优化算法使其可以解决多序列比对问题,最后给出利用粒子群优化算法求解多序列比对的算法,及其测试结果。  相似文献   
In a previous paper, we analysed the impact of renewable energy intermittency on the operational characteristics of hydrogen energy systems with pre-set Power Management Strategies not subject to optimisation. The research presented in this follow-up paper extends that earlier work and demonstrates the validity of applying Particle Swarm Optimisation (PSO) to size and optimise hydrogen systems. Specifically, PSO is used to iteratively converge on the (short-term) battery capacity (Ah) and hydrogen storage (L) in addition to defining the switching parameters which a Power Management Strategy (PMS) uses. The PSO algorithm is guided by three operational objective functions and conducted using MATLAB/Simulink. Simulations also incorporate laboratory resolved device characteristics.  相似文献   
Waste Electrical and Electronic Equipments (WEEEs) are one of the most significant waste streams in modern societies. In the past decade, disassembly of WEEE to support remanufacturing and recycling has been growingly adopted by industries. With the increasing customisation and diversity of Electrical and Electronic Equipment (EEE) and more complex assembly processes, full disassembly of WEEE is rarely an ideal solution due to high disassembly cost. Selective disassembly, which prioritises operations for partial disassembly according to the legislative and economic considerations of specific stakeholders, is becoming an important but still a challenging research topic in recent years. In order to address the issue effectively, in this paper, a Particle Swarm Optimisation (PSO)-based selective disassembly planning method embedded with customisable decision making models and a novel generic constraint handling algorithm has been developed. With multi-criteria and adaptive decision making models, the developed method is flexible to handle WEEE to meet the various requirements of stakeholders. Based on the generic constraint handling and intelligent optimisation algorithms, the developed research is capable to process complex constraints and achieve optimised selective disassembly plans. Industrial cases on Liquid Crystal Display (LCD) televisions have been used to verify and demonstrate the effectiveness and robustness of the research in different application scenarios.  相似文献   
Particle swarm optimisation (PSO) is an evolutionary metaheuristic inspired by the swarming behaviour observed in flocks of birds. The applications of PSO to solve multi-objective discrete optimisation problems are not widespread. This paper presents a PSO algorithm with negative knowledge (PSONK) to solve multi-objective two-sided mixed-model assembly line balancing problems. Instead of modelling the positions of particles in an absolute manner as in traditional PSO, PSONK employs the knowledge of the relative positions of different particles in generating new solutions. The knowledge of the poor solutions is also utilised to avoid the pairs of adjacent tasks appearing in the poor solutions from being selected as part of new solution strings in the next generation. Much of the effective concept of Pareto optimality is exercised to allow the conflicting objectives to be optimised simultaneously. Experimental results clearly show that PSONK is a competitive and promising algorithm. In addition, when a local search scheme (2-Opt) is embedded into PSONK (called M-PSONK), improved Pareto frontiers (compared to those of PSONK) are attained, but longer computation times are required.  相似文献   
Railway timetabling is an important process in train service provision as it matches the transportation demand with the infrastructure capacity while customer satisfaction is also considered. It is a multi-objective optimisation problem, in which a feasible solution, rather than the optimal one, is usually taken in practice because of the time constraint. The quality of services may suffer as a result. In a railway open market, timetabling usually involves rounds of negotiations amongst a number of self-interested and independent stakeholders and hence additional objectives and constraints are imposed on the timetabling problem. While the requirements of all stakeholders are taken into consideration simultaneously, the computation demand is inevitably immense. Intelligent solution-searching techniques provide a possible solution. This paper attempts to employ a particle swarm optimisation (PSO) approach to devise a railway timetable in an open market. The suitability and performance of PSO are studied on a multi-agent-based railway open-market negotiation simulation platform.  相似文献   
为了提高网络入侵检测率,提出一种反向学习粒子群算法和多层次分类器相融合的网络入侵检测模型。首先将反向学习粒子群算法优化最小二乘支持向量机,以提高分类性能;然后利用由粗到精策略构造多层的网络入侵分类器降低计算时间杂度复;最后采用KDD 99数据集进行仿真测试。仿真结果表明,相对于其他检测模型,该模型不仅提高了网络入侵检测率,降低了入侵检测误报率,同时加快了入侵检测速度,为网络安全提供了有效保证。  相似文献   
资源合理调度是云计算研究热点。针对混合蛙跳算法不足,提出一种改进混合蛙跳算法的云计算资源调度策略(ISF-LA)。首先在局部寻优过程中引入粒子更新思想,加快收敛速度,然后在全局寻优中对最优个体进行混沌扰动,降低局部最优出现的概率,最后在CloudSim平台进行仿真实验。结果表明,ISFLA缩短了云计算任务的完成时间,资源的负载分配更加合理。  相似文献   
将粒子群算法运用于求解柔性作业车间调度问题,采用基于轮盘赌的编码方法以及基于邻域互换的局部搜索方法。通过两个不同规模算例的试验计算,与基于粒子位置取整的编码方法进行对比分析,说明了轮盘赌编码方法求解柔性作业车间调度问题的有效性。且采用该编码方法的混合粒子群算法在求解柔性作业车间调度问题时具有更好的求解性能。  相似文献   
基于图像信息,实现对物体的三维重构在交通、地质等领域具有重要的应用价值,对此首先要建立图像坐标和大地坐标的对应关系,而这种关系涉及到摄像机的内部及外部参数,这就需要对摄像机进行标定,确定其参数. 利用几何关系给出坐标系间的关系模型,以标定板上关键点间的实际距离和理论距离的相对误差绝对值为目标,将参数确定问题转化为非线性优化问题,进而利用PSO算法对优化模型进行求解,实现对摄像机的自标定. 通过实际图像的采集并进行数值计算,结果表明模型正确,与其他算法相比,计算精度得到显著提高.  相似文献   
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